PLAUR Protein (AA 23-305) (Fc Tag)

Catalog No. ABIN7275406

Product Details

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Protein Type: Recombinant

Protein Characteristics: AA 23-305

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PLAUR protein is labelled with Fc Tag.

Purpose: Human uPAR/PLAUR Protein

Sequence: Leu23-Gly305

Characteristics: Recombinant Human uPAR/PLAUR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Gly305.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human PLAU, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 10.3ng/ml determined by ELISA. See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: uPAR (PLAUR Products)

Synonyms: Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein

Background: The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.

Molecular Weight: 58.2 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Pathways: Inositol Metabolic Process