Browse our IFNGR1 Proteins (IFNGR1)

On are 30 Interferon gamma Receptor 1 (IFNGR1) Proteins from 10 different suppliers available. Additionally we are shipping IFNGR1 Antibodies (188) and IFNGR1 Kits (12) and many more products for this protein. A total of 249 IFNGR1 products are currently listed.
CD119, DKFZp469K1232, Ifgr, IFN-gammaR, Ifngr, ifngr1, MGC129098, MGC194858, MGC194873, Nktar, zgc:194858
list all proteins Gene Name GeneID UniProt
IFNGR1 3459 P15260
IFNGR1 15979 P15261
IFNGR1 116465  

IFNGR1 Proteins (IFNGR1) by Origin

More Proteins for IFNGR1 Interaction Partners

Cow (Bovine) Interferon gamma Receptor 1 (IFNGR1) interaction partners

  1. analysis of mir (show MYLIP Proteins)-378 and of the interferon gamma receptor 1 protein at different stages of luteal development showed that mir (show MYLIP Proteins)-378 decreased the expression of interferon gamma receptor 1 protein but not the mRNA

  2. SNPs in IFNG (show IFNG Proteins), IFNGR1 and R2, IL22 (show IL22 Proteins), and IL22RA1 (show IL22RA1 Proteins) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.

Zebrafish Interferon gamma Receptor 1 (IFNGR1) interaction partners

  1. The receptor complex for Ifn-gamma2 includes cytokine receptor (show LEPR Proteins) family B (Crfb)6 together with Crfb13 and Crfb17.

Human Interferon gamma Receptor 1 (IFNGR1) interaction partners

  1. Data suggest IFNG (show IFNG Proteins) plays various roles in dynamics of inflammation in subjects with underlying autoimmunity modeled as "canonical" and "non-canonical" pathways; in canonical pathway, IFNG (show IFNG Proteins) dimerizes and binds to IFNGR1 in IFNGR1/IFNGR2 (show IFNGR2 Proteins) hetero-multimer; STAT (show STAT1 Proteins) transcription factors are involved in non-canonical pathway. (IFNG (show IFNG Proteins) = interferon gamma (show IFNG Proteins); IFNGR = IFNG (show IFNG Proteins) receptor; STAT (show STAT1 Proteins) = signal transducers and activators of transcription)

  2. The study did not provide enough powerful evidence to identify a significant association between IFNGR1 -56C/T polymorphism and tuberculosis susceptibility (meta-analysis).

  3. All patients tested were positive for mycobacteria; one was heterozygous for the IFNGR1 exon 5 single-nucleotide-missense substitution

  4. The deletion of IFNGR1 causes complete IFN-gammaR1 deficiency. Despite the deletion ending very close to the IL22RA2 (show IL22RA2 Proteins) gene, it does not appear to affect IL22RA2 (show IL22RA2 Proteins) transcription.

  5. A significant association of IFN-gammaR1 and P2X7 (show P2RX7 Proteins) genes polymorphisms with risk of developing TB in Iranian population.

  6. Mendelian susceptibility to mycobacteria due to a partial dominant mutation of the interferon gamma receptor 1 gene.

  7. Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum

  8. Statistical analyses revealed that four genetic variants in IFNGR1 were marginally associated with the risk of Tuberculosis (P = 0.02-0.04), while other single nucleotide polymorphisms in IFNGR1 and IFNGR2 (show IFNGR2 Proteins) did not exhibit any associations

  9. Uniformly low expression of IFN and IFNGR1 in post Kala-azar dermal leishmaniasis skin biopsies could explain parasite persistence and is consistent with prior demonstration of genetic association with IFNGR1 polymorphisms.

  10. In an African-American population, a significant difference in IFNGR1 expression between patients with RA and controls. However, IFNGR1 expression levels were not statistically significantly associated with erosion status or other radiographic outcomes.

Mouse (Murine) Interferon gamma Receptor 1 (IFNGR1) interaction partners

  1. These results suggest that pulmonary C-fibers affect IFNGR1 expression by inducing IFN-alpha (show IFNA Proteins) to regulate IFN-gamma (show IFNG Proteins)-mediated airway inflammation and airway hyperresponsiveness.

  2. data define a novel B cell-intrinsic IFN-gammaR signaling pathway specific to Spt (show AGXT Proteins)-GC development and autoimmunity.

  3. These data offer direct evidence that tumor cell loss of the IFNGR1 gene, which results in loss of IFN-g (show IFNG Proteins) signaling, leads to resistance to anti-CTLA-4 (show CTLA4 Proteins) therapy.

  4. These data indicate that both GKO and GRKO mice fail to develop an IFN-gamma (show IFNG Proteins)-mediated antiviral response, but differ in regulation of the inflammatory response to infection.

  5. IFN-gamma (show IFNG Proteins) Ralpha is a key determinant of CD8 (show CD8A Proteins)+ T cell-mediated tumor elimination or tumor escape and relapse in FVB mouse.

  6. Data indicate that prolonged IFNgammaR-/- dendritic cell survival promotes CD4 (show CD4 Proteins) T cell expansion.

  7. These data suggest that type I IFN stimulation induces a rapid recruitment of a repressive Egr3 (show EGR3 Proteins)/Nab1 (show NAB1 Proteins) complex that silences transcription from the ifngr1 promoter.

  8. IFNGR1 transcription is mediated by CTCF (show CTCF Proteins) protein.

  9. results suggest that NOD macrophages have a selective defect in IFN-gamma (show IFNG Proteins) but not IFN-alpha (show IFNA Proteins)/beta receptor pathway

  10. Gamma interferon (IFN-gamma (show IFNG Proteins)) receptor restricts systemic dengue virus replication and prevents paralysis in IFN-alpha (show IFNA Proteins)/beta receptor-deficient mice.

IFNGR1 Protein Profile

Protein Summary

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Alternative names and synonyms associated with IFNGR1

  • interferon gamma receptor 1 (IFNGR1)
  • zgc:194873 (zgc:194873)
  • interferon gamma receptor 1 (ifngr1)
  • interferon gamma receptor 1 (Ifngr1)
  • CD119 protein
  • DKFZp469K1232 protein
  • Ifgr protein
  • IFN-gammaR protein
  • Ifngr protein
  • ifngr1 protein
  • MGC129098 protein
  • MGC194858 protein
  • MGC194873 protein
  • Nktar protein
  • zgc:194858 protein

Protein level used designations for IFNGR1

interferon gamma receptor 1 , AVP, type 2 , CD119 antigen , CDw119 , IFN-gamma receptor 1 , IFN-gamma-R1 , antiviral protein, type 2 , immune interferon receptor 1 , interferon-gamma receptor alpha chain , INF-g receptor , interferon-gamma receptor 1

421685 Gallus gallus
476216 Canis lupus familiaris
508619 Bos taurus
571368 Danio rerio
704571 Macaca mulatta
747276 Pan troglodytes
780275 Xenopus (Silurana) tropicalis
100171593 Pongo abelii
100423877 Macaca mulatta
100598615 Nomascus leucogenys
3459 Homo sapiens
15979 Mus musculus
116465 Rattus norvegicus
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