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IFNGR1 Protein (His tag)

IFNGR1 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319381
  • Target See all IFNGR1 Proteins
    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
    Protein Type
    Recombinant
    Origin
    • 11
    • 11
    Human
    Source
    • 7
    • 5
    • 5
    • 4
    • 1
    Human Cells
    Purification tag / Conjugate
    This IFNGR1 protein is labelled with His tag.
    Purpose
    Recombinant Human IFNGR1 Protein (His Tag)
    Sequence
    Glu18-Ser245
    Characteristics
    Recombinant Human Interferon gamma receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser245 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IFNGR1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
    Alternative Name
    IFNGR1 (IFNGR1 Products)
    Synonyms
    CD119 Protein, IFNGR Protein, IFN-gammaR Protein, Ifgr Protein, Ifngr Protein, Nktar Protein, IFNGR1 Protein, MGC129098 Protein, ifngr1 Protein, MGC194858 Protein, MGC194873 Protein, zgc:194858 Protein, cd119 Protein, ifngr Protein, DKFZp469K1232 Protein, interferon gamma receptor 1 Protein, cytokine receptor family member B17 Protein, IFNGR1 Protein, Ifngr1 Protein, crfb17 Protein, ifngr1 Protein
    Background

    Background: Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

    Synonym: CD119,IFNGR,IMD27A,IMD27B,Interferon gamma receptor 1,IFNGR1

    Molecular Weight
    28.7 kDa
    UniProt
    P15260
    Pathways
    Interferon-gamma Pathway
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