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Browse our Death-Domain Associated Protein Proteins (DAXX)

Full name:
Death-Domain Associated Protein Proteins (DAXX)
On www.antibodies-online.com are 12 Death-Domain Associated Protein (DAXX) Proteins from 5 different suppliers available. Additionally we are shipping Death-Domain Associated Protein Antibodies (298) and Death-Domain Associated Protein Kits (35) and many more products for this protein. A total of 362 Death-Domain Associated Protein products are currently listed.
Synonyms:
BING2, DAP6, EAP1, im:6905684, LOC100226911
list all proteins Gene Name GeneID UniProt
DAXX 1616 Q9UER7
DAXX 140926  
DAXX 13163 O35613

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Death-Domain Associated Protein Proteins (DAXX) by Origin

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More Proteins for Death-Domain Associated Protein Interaction Partners

Human Death-Domain Associated Protein (DAXX) interaction partners

  1. The interaction of Daxx C-terminal domain and androgen receptor (show AR Proteins) suppresses cholesterol synthesis.Daxx C-terminal domain binds directly to androgen receptor (show AR Proteins).

  2. HDAC1 (show HDAC1 Proteins) and DAXX are co-repressors associated with epigenetic regulation that help to control promoter histone acetylation reactions involved in regulating GAD67 (show GAD1 Proteins).

  3. We provide an overview of the individual components (ATRX, DAXX and/or H3.3) tested in each study and propose a model where the ATRX/DAXX chaperone complex deposits H3.3 to maintain the H3K9me3 modification at heterochromatin throughout the genome.

  4. Daxx and Atrx (show ATRX Proteins) safeguard the genome by silencing repetitive elements when DNA methylation (show HELLS Proteins) levels are low.

  5. Studies of the dynamics of the response of PML (show PML Proteins) nuclear body components and IFI16 (show IFI16 Proteins) to invading herpes simplex virus 1 genomes demonstrated that human Daxx (hDaxx) and IFI16 (show IFI16 Proteins) respond more rapidly than PML (show PML Proteins).

  6. identifying Daxx as a broad cellular inhibitor of reverse-transcription. Altogether, these findings unravel a novel antiviral function for PML (show PML Proteins) and PML (show PML Proteins) nuclear body-associated protein Daxx

  7. PML (show PML Proteins), hDaxx and Sp100 (show SP100 Proteins) primarily act as cellular restriction factors during lytic human cytomegalovirus replication and during the dynamic process of reactivation but do not serve as key determinants for the establishment of latency.

  8. ATRX (show ATRX Proteins)- and DAXX-deficient PNETs have distinct genome-wide DNA methylation (show HELLS Proteins) profiles. Loss of DAXX and not ATRX (show ATRX Proteins) appears to be the driver event in altering genome-wide methylation changes in PNETs.

  9. These findings collectively support a DAXX-centric pathway for telomere maintenance, where DAXX interaction with the telomerase regulates telomerase assembly in Cajal bodies and telomerase targeting to telomeres.

  10. Knock-down of the cellular DAXX protein modulates the human papillomavirus genome replication and transcription in U2OS cells--papillomavirus replication is reduced in the absence of this component of ND10.

Mouse (Murine) Death-Domain Associated Protein (DAXX) interaction partners

  1. Daxx and Atrx (show ATRX Proteins) safeguard the genome by silencing repetitive elements when DNA methylation (show HELLS Proteins) levels are low.

  2. The protein levels of Daxx is reduced in Stella (show DPPA3 Proteins)-null oocytes and embryos.

  3. Daxx selectively represses IL-6 (show IL6 Proteins) transcription through HDAC1 (show HDAC1 Proteins)-mediated histone deacetylation

  4. Overall, these data imply a regulatory role for Daxx in reovirus-induced apoptosis, depending on its location in the nucleus or cytoplasm.

  5. phosphorylation of Daxx by RIP3 comprises an important part of ischemic necrosis in rat retinal ganglion cells

  6. DAXX is associated with regulatory regions of selected activity-regulated genes, where it promotes H3.3 loading upon membrane depolarization. DAXX loss not only affects H3.3 deposition but also impairs transcriptional induction of these genes.

  7. Daxx, a HIPK kinase substrate in the apoptosis pathway, was phosphorylated by HIPK3 (show HIPK3 Proteins) at Ser (show SIGLEC1 Proteins)-669 in response to cAMP stimulation.

  8. Neither Daxx nor PML (show PML Proteins), the main players of ND10-based immunity, are required for the block to viral gene expression in the S/G2 (show STRN3 Proteins) phase.

  9. HIRA (show HIRA Proteins) interacts with H3.3/H4 in the absence of Daxx.

  10. Both Daxx and macrophage Ste20-like kinase (MST)1 (show STK4 Proteins) are key mediators of microglial cell death induced by the proinflammatory cytokine interferon (IFN)-gamma (show IFNA Proteins).

Death-Domain Associated Protein (DAXX) Protein Profile

Protein Summary

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Death-Domain Associated Protein (DAXX)

  • death associated protein 3 (dap3)
  • death associated protein 3 (LOC100226911)
  • death associated protein 3 (DAP3)
  • death-domain associated protein (DAXX)
  • death-domain associated protein (Daxx)
  • Fas death domain-associated protein (Daxx)
  • BING2 protein
  • DAP6 protein
  • EAP1 protein
  • im:6905684 protein
  • LOC100226911 protein

Protein level used designations for DAXX

28S ribosomal protein S29, mitochondrial , death associated protein 3 , 28S ribosomal protein S29, mitochondrial-like , CENP-C binding protein , ETS1-associated protein 1 , Fas-binding protein , death domain-associated protein 6 , death-associated protein 6 , fas death domain-associated protein , Fas death domain-associated protein , death-domain associated protein

GENE ID SPECIES
559007 Danio rerio
100226911 Taeniopygia guttata
100394329 Callithrix jacchus
1616 Homo sapiens
140926 Rattus norvegicus
504336 Bos taurus
474873 Canis lupus familiaris
100524813 Sus scrofa
13163 Mus musculus
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