DAXX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for DAXX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2719230)
Target
See all DAXX ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This DAXX protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human DAXX (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Death-Domain Associated Protein (DAXX) (AA 1-739) protein (His tag)
custom-made DAXX Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Death-Domain Associated Protein (DAXX) (AA 1-740) protein (His tag)custom-made DAXX Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Death-Domain Associated Protein (DAXX) (AA 1-740) protein (GST tag)DAXX Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Death-Domain Associated Protein (DAXX) (AA 1-233), (partial) protein (GST tag)DAXX Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Death-Domain Associated Protein (DAXX) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DAXX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Death-Domain Associated Protein (DAXX) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DAXX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- DAXX (Death-Domain Associated Protein (DAXX))
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Alternative Name
- Daxx
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Background
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 81.2 kDa
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NCBI Accession
- NP_001135441
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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