Browse our K(lysine) Acetyltransferase 5 Proteins (KAT5)

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K(lysine) Acetyltransferase 5 Proteins (KAT5)
On are 14 K(lysine) Acetyltransferase 5 (KAT5) Proteins from 6 different suppliers available. Additionally we are shipping K(lysine) Acetyltransferase 5 Antibodies (163) and K(lysine) Acetyltransferase 5 Kits (4) and many more products for this protein. A total of 197 K(lysine) Acetyltransferase 5 products are currently listed.
6121, AI839539, CG6121, CPLA2, DmEG0007.7, Dmel/TIP60, Dmel\\CG6121, Dmel\\TIP60, dmHAG405, dTip60, EG0007.7, EG:EG0007.7, ESA1, Htatip, Htatip1, im:6908768, PLIP, TIP, Tip55, Tip60, wu:fb55b08, ZC2HC5, zgc:110752
list all proteins Gene Name GeneID UniProt
KAT5 10524 Q92993
KAT5 81601 Q8CHK4
KAT5 192218 Q99MK2

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K(lysine) Acetyltransferase 5 Proteins (KAT5) by Origin

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Top referenced K(lysine) Acetyltransferase 5 Proteins

  1. Human KAT5 Protein expressed in Wheat germ - ABIN3170498 : Kurash, Lei, Shen, Marston, Granda, Fan, Wall, Li, Gaudet: Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo. in Molecular cell 2008 (PubMed)

More Proteins for K(lysine) Acetyltransferase 5 Interaction Partners

Fruit Fly (Drosophila melanogaster) K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. Our results implicate Tip60 as a critical mediator of EE-induced benefits, and provide broad insights into synergistic behavioral and epigenetic based therapeutic approaches for treatment of cognitive disorder.

  2. compromising Tip60 histone acetyltransferase activity in the CySC (show CST3 Proteins) lineage recapitulates loss-of-function phenotypes of E(Pc), suggesting that Tip60 and E(Pc) act together, consistent with published biochemical data.

  3. Heat Shock Factor recruits the dTip60 complex to the hsp70 loci in cells treated with salicylate, which triggers chromatin remodeling at these loci without transcription activation.

  4. Excess Tip60 exerts a neuroprotective role in axonal transport and functional locomotion defects in an animal model of Alzheimer's disease.

  5. a novel mechanism for Tip60 mediated sleep-wake regulation via control of axonal growth and PDF levels within the small ventrolateral neurons-encompassing neural network

  6. a functional interaction between Tip60 and APP (show APP Proteins) in mediating nervous system development and apoptotic neuronal cell death

  7. The role of Tip60 HAT activity in transcriptional control during multicellular development in vivo, was investigated.

  8. Ubiquitous dTip60 knock-down in flies was lethal, whereas knock-down in the wing imaginal disk led to developmental defects.

  9. demonstrated that the dTip60 chromatin-remodeling complex acetylates nucleosomal phospho-H2Av (show H2AFV Proteins) and exchanges it with an unmodified H2Av (show H2AFV Proteins); both the histone acetyltransferase dTip60 and the atpase Domino/p400 catalyze the exchange of phospho-H2Av (show H2AFV Proteins)

  10. TIP60 complex can promote the generation of silent chromatin.

Human K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. TIP60 complex regulates bivalent chromatin recognition/modification by 53BP1 (show TP53BP1 Proteins) through direct H4K20me binding and H2AK15 acetylation.

  2. Studies suggest that lysine (K) acetyltransferase inhibitors (KATi (show CCBL1 Proteins)) are important for providing personalized therapies.

  3. Thus Tip60 interacts with RNR (show NR2E3 Proteins) and NME3 (show NME3 Proteins) to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs.

  4. TIP60 acted downstream of UHRF2 (show UHRF2 Proteins) to regulate H3K9ac and H3K14ac expression.

  5. Data provide evidence that the acetylation of H2AX (show H2AFX Proteins) at Lys5 (show AASDHPPT Proteins) by TIP60 is required for the (ADPribosyl) ation activity and the dynamic binding of PARP-1 (show PARP1 Proteins) to chromatin after the induction of DNA damage.

  6. Synthetic lethality screening identifies TIP60-dependent radiation sensitivity in the absence of BAF180 (show PBRM1 Proteins).

  7. E1A (show BCKDHA Proteins) 243R promotes association of MYC (show MYC Proteins)/MAX with the NuA4/Tip60 complex, implicating the importance of the MYC (show MYC Proteins)/NuA4 pathway in cellular transformation by both MYC (show MYC Proteins) and E1A (show BCKDHA Proteins).

  8. UV irradiation enhanced the binding of ATF3 (show ATF3 Proteins) to Tip60, knockdown of ATF3 (show ATF3 Proteins) expression decreased Tip60 stability, thereby impairing Tip60 induction by UV irradiation.

  9. KAT5 is significantly elevated in malignant pleural mesothelioma

  10. Data suggest the combination of histone acetyltransferase TIP60 and microRNA miR (show MLXIP Proteins)-22 as prognostic indicator of breast cancer progression.

Mouse (Murine) K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. these results identify a new compaction pathway of mammalian pericentric heterochromatin relying on Tip60 that might be dependent on BRD2 (show BRD2 Proteins) recruitment by H4K12 acetylation.

  2. The expression of putative SOX4 target genes during myoblast differentiation is specifically regulated by the molecular switching of the co-activator KAT5 and the co-repressor HDAC1 on SOX4 transcriptional activation.

  3. TIP60 K327 acetylation allows TIP60 to switch binding partners. conditional knockout in Treg cells results in autoimmune disease.

  4. Allele compensation in tip60+/- mice rescues white adipose tissue function in vivo.

  5. Tip60 hyperacetylates histone H4 in Ras-transformed cells.Tip60 coordinates histone acetylation at both local and global levels to facilitate Ras-induced transformation.

  6. RGS6 (show RGS6 Proteins) suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 (show DNMT1 Proteins) degradation and promoting apoptosis

  7. Early adipogenesis is regulated through USP7 (show USP7 Proteins)-mediated deubiquitination of the histone acetyltransferase TIP60.

  8. SLX2 interacts with synaptonemal complex central element protein 2 (SYCE2 (show SYCE2 Proteins)) and histone acetyltransferase TIP60.

  9. these results suggest that Tip60 binds with Pax6 (show PAX6 Proteins) and that this physical interaction leads to the full-transcriptional activation of Pax6 (show PAX6 Proteins) during retina development.

  10. Tip60 may function in a tumor suppressor pathway(s) to maintain adult cardiomyocytes in replicative senescence.

K(lysine) Acetyltransferase 5 (KAT5) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Alternative names and synonyms associated with K(lysine) Acetyltransferase 5 (KAT5)

  • zgc:92510 (zgc:92510)
  • K(lysine) acetyltransferase 5 (LOC100340634)
  • CG6121 gene product from transcript CG6121-RA (Tip60)
  • histone acetyltransferase Tip60 (Tip60)
  • tip60 (AaeL_AAEL014072)
  • tip60 (Smp_053140)
  • HIV-1 tat interactive protein, homolog (human) (htatip)
  • K(lysine) acetyltransferase 5 (KAT5)
  • K(lysine) acetyltransferase 5 (Kat5)
  • 6121 protein
  • AI839539 protein
  • CG6121 protein
  • CPLA2 protein
  • DmEG0007.7 protein
  • Dmel/TIP60 protein
  • Dmel\\CG6121 protein
  • Dmel\\TIP60 protein
  • dmHAG405 protein
  • dTip60 protein
  • EG0007.7 protein
  • EG:EG0007.7 protein
  • ESA1 protein
  • Htatip protein
  • Htatip1 protein
  • im:6908768 protein
  • PLIP protein
  • TIP protein
  • Tip55 protein
  • Tip60 protein
  • wu:fb55b08 protein
  • ZC2HC5 protein
  • zgc:110752 protein

Protein level used designations for KAT5

K(lysine) acetyltransferase 5 , CG6121-PA , CG6121-PB , CG6121-PC , Tat-interactive protein , Tip60-PA , Tip60-PB , Tip60-PC , histone acetyltransferase Tip60 , tip60 , HIV-1 tat interactive protein , 60 kDa Tat-interactive protein , HIV-1 Tat interactive protein, 60kDa , K-acetyltransferase 5 , Tat interacting protein, 60kDa , cPLA(2)-interacting protein , cPLA2 interacting protein , histone acetyltransferase HTATIP , histone acetyltransferase KAT5 , HIV-1 tat interactive protein 1, 60 kDa homolog , HIV-1 tat interactive protein 1, homolog , Tat-interactive protein-60 , lysine acetyltransferase 5 , HIV-1 Tat interacting protein, 60kDa , HIV-1 Tat interactive protein 60 kD , HIV-1 Tat interactive protein, 60 kD , HIV-1 tat interactive protein, homolog , Histone acetyltransferase HTATIP

436638 Danio rerio
100340634 Oryctolagus cuniculus
31362 Drosophila melanogaster
413101 Apis mellifera
5579231 Aedes aegypti
8344228 Schistosoma mansoni
503731 Danio rerio
10524 Homo sapiens
81601 Mus musculus
483728 Canis lupus familiaris
505619 Bos taurus
192218 Rattus norvegicus
451329 Pan troglodytes
100174410 Pongo abelii
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