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Browse our PARK7 Proteins (PARK7)

Full name:
Parkinson Protein 7 Proteins (PARK7)
On www.antibodies-online.com are 31 Parkinson Protein 7 (PARK7) Proteins from 15 different suppliers available. Additionally we are shipping PARK7 Antibodies (252) and PARK7 Kits (20) and many more products for this protein. A total of 313 PARK7 products are currently listed.
Synonyms:
CAP1, DJ-1, DJ1, SP22, zgc:103725
list all proteins Gene Name GeneID UniProt
PARK7 57320 Q99LX0
PARK7 11315 Q99497
PARK7 117287 O88767

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PARK7 Proteins (PARK7) by Origin

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Top referenced PARK7 Proteins

  1. Human PARK7 Protein expressed in Escherichia coli (E. coli) - ABIN667043 : Choi, Sullards, Olzmann, Rees, Weintraub, Bostwick, Gearing, Levey, Chin, Li: Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for ABIN667043

More Proteins for PARK7 Interaction Partners

Zebrafish Parkinson Protein 7 (PARK7) interaction partners

  1. Melatonin, added together with MPTP (show PTPN2 Proteins) or added once MPTP (show PTPN2 Proteins) was removed, prevented and recovered, respectively, the parkinsonian phenotype once it was established, restoring gene expression and normal function of the parkin (show PARK2 Proteins)/PINK1 (show PINK1 Proteins)/DJ-1/MUL1 loop and also the normal motor activity of the embryos.

  2. These studies show that zDJ-1 is very similar to human DJ-1 and is evolutionarily conserved and expressed in dopaminergic neurons.

Mouse (Murine) Parkinson Protein 7 (PARK7) interaction partners

  1. DJ-1(-/-) astrocytes may provide decreased neuroprotection to surrounding neurons due to alterations in pro-inflammatory mediator expression

  2. Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.

  3. To verify our finding, we provide evidence that the protein expression of Parkinson protein 7, including new protein synthesis, is sensitive to mTORC1 inhibition

  4. These observations reveal an unexpected differential role of DJ-1 in the development of nTregs and iTregs.

  5. A comprehensive analysis of influence of the Parkinson disease-associated genes Parkin (show PARK2 Proteins) and DJ-1 on neurotransmitter receptor (show GRIN1 Proteins) expression in mice

  6. this study identified the anti-oxidant protein DJ-1 as being capable of protecting pancreatic islet cells from cell death induced by an inflammatory and cytotoxic setting.

  7. In skeletal muscle cells, DJ-1 contributes to undernutrition-induced atrophy via MAPKs/ubiquitin ligase pathway.

  8. Deficiency of DJ-1 exerts a stimulatory effect on vascular smooth muscle cell migration.

  9. DJ1 maintains cellular metabolic homeostasis via modulating ROS (show ROS1 Proteins) levels in murine skeletal muscles, revealing a role of DJ1 in maintaining efficient fuel utilization.

  10. DJ-1 physically binds the 20S proteasome (show PSMA5 Proteins) and inhibits its activity. following oxidative stress, DJ-1 is involved in the Nrf2 (show NFE2L2 Proteins)-dependent oxidative stress response that leads to the upregulation of both the 20S proteasome (show PSMA5 Proteins) and its regulator, NQO1 (show NQO1 Proteins).

Human Parkinson Protein 7 (PARK7) interaction partners

  1. ELISA-based detection of flotillin 2 (show FLOT2 Proteins) and PARK7 showed that the combination of these proteins was able to distinguish prostate cancer patients and healthy controls with 68% sensitivity and 93% specificity

  2. Furthermore, SIRT1 (show SIRT1 Proteins) activity was reduced in DJ-1-knockout cells, and this reduced activity was restored by re-introduction of wild-type DJ-1 but not of C106-mutant DJ-1 into DJ-1-knockout cells. It is first report showing direct connection of DJ-1 with SIRT1 (show SIRT1 Proteins).

  3. DJ-1 is necessary for 20C-mediated protection against rotenone-induced oxidative damage, at least in part, by activating PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling, and subsequently enhancing the nuclear accumulation of Nrf2 (show GABPA Proteins).

  4. The aberrant up-regulation of DJ-1 expression might be an important step in the pathogenesis of cervical carcinoma.

  5. Association of early onset Parkinson' and severe clinical signs with multiple alterations in DJ1 in Turkish patients.

  6. the important role of PARK7 in cisplatin induced apoptosis in clear renal cell carcinoma (show MOK Proteins) cells

  7. Such a mode of matrix localization of DJ-1 is difficult to explain by conventional mechanisms and implies a unique matrix import mechanism for DJ-1 mutants.

  8. Serum levels of thioredoxin (show TXN Proteins) and DJ-1 were significantly higher in non-small cell lung cancer patients; therefore, these may be utilized as novel diagnostic and prognostic biomarkers for non-small cell lung cancer

  9. The L10P DJ-1 mutation results in a toxic protein, which lacks the protective function of wild-type protein on mitochondria due to the decrease in the ability of anti-oxidative stress

  10. DJ-1 is increased in elderly lung cancer patients with malignant pleural effusions and may have a role in redox regulation

Pig (Porcine) Parkinson Protein 7 (PARK7) interaction partners

  1. The PARK7 gene was demonstrated to be located on porcine chromosome 6

PARK7 Protein Profile

Protein Summary

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Alternative names and synonyms associated with PARK7

  • parkinson disease (autosomal recessive, early onset) 7 (park7)
  • Parkinson disease (autosomal recessive, early onset) 7 (PARK7)
  • Parkinson disease (autosomal recessive, early onset) 7 (Park7)
  • parkinson protein 7 (PARK7)
  • parkinson protein 7 (Park7)
  • CAP1 protein
  • DJ-1 protein
  • DJ1 protein
  • SP22 protein
  • zgc:103725 protein

Protein level used designations for Parkinson Protein 7 Proteins (PARK7)

DJ-1 protein , parkinson disease protein 7 homolog , protein DJ-1 , zDJ-1 , Parkinson disease 7 , RNA-binding protein regulatory subunit , Parkinson disease (autosomal recessive, early onset) 7 , oncogene DJ1 , contraception-associated protein 1 , fertility protein SP22

GENE ID SPECIES
449674 Danio rerio
395277 Gallus gallus
57320 Mus musculus
11315 Homo sapiens
511268 Bos taurus
117287 Rattus norvegicus
479595 Canis lupus familiaris
780404 Sus scrofa
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