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Browse our PMEPA1 Proteins (PMEPA1)

Full name:
Prostate Transmembrane Protein, Androgen Induced 1 Proteins (PMEPA1)
On www.antibodies-online.com are 8 Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) Proteins from 4 different suppliers available. Additionally we are shipping PMEPA1 Antibodies (26) and PMEPA1 Kits (3) and many more products for this protein. A total of 42 PMEPA1 products are currently listed.
Synonyms:
2210418I02Rik, AW455466, Erg1.2, N4wbp4, PMEPA1, Stag1, tmepai, zgc:92731
list all proteins Gene Name GeneID UniProt
Rat PMEPA1 PMEPA1 311676  
PMEPA1 56937 Q969W9
PMEPA1 65112  

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PMEPA1 Proteins (PMEPA1) by Origin

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More Proteins for PMEPA1 Interaction Partners

Human Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) interaction partners

  1. these findings indicated that PMEPA1 participates in TGF-beta (show TGFB1 Proteins)- and hypoxia-regulated gene expression networks in solid tumors and thereby may contribute to tumor progression.

  2. the present study suggest that the upregulation of miR19a3p expression levels contributes to tumor progression and that one of its underlying mechanisms involves inhibition of PMEPA1 expression.

  3. Sp1 (show PSG1 Proteins) up-regulated TMEPAI protein expression, as well as Sp1 (show PSG1 Proteins) promoting TMEPAI-induced cell proliferation.

  4. PMEPA1 was upregulated in breast cancer cell lines as well as in a set of clinical invasive breast ductal carcinomas. Interestingly, depletion of PMEPA1 decreased breast cancer stem cell (CSC)-enriched populations, while ectopic overexpression of PMEPA1 increased breast CSC-enriched populations.

  5. these data elaborated on the diverse activity among TCF (show HNF4A Proteins)/LEF family members with respect to the transcriptional regulation of the TMEPAI gene.

  6. Data show that over-expressed transmembrane prostate androgen-induced protein 1 (PMEPA1) can promote cell migration and maintain the mesenchymal-like morphology of breast cancer cells.

  7. Data show that silencing of PMEPA1 protein facilitates the growth of prostate cancer cells and modulates androgen receptor (AR (show AR Proteins)) through NEDD4 (show NEDD4 Proteins) ubiquitin protein ligase (show UBE2K Proteins) and PTEN protein.

  8. Downregulation of PMEPA1 may result in increased androgen receptor (show AR Proteins) protein levels and function in cancer of the prostate cells, contributing to prostate tumorigenesis.

  9. EGF (show EGF Proteins) signaling collaboratively regulates TGF-beta (show TGFB1 Proteins)-induced TMEPAI expression.

  10. TMEPAI is translocated on the lysosome and late endosome, and that association with Nedd4 (show NEDD4 Proteins) is required for the transport of TMEPAI to the lysosome.

Mouse (Murine) Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1) interaction partners

  1. Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins)/TCF7L2 (show TCF7L2 Proteins) pathway is preferentially able to alter the transcriptional regulation of the TGF-beta (show TGFB1 Proteins)-target gene, TMEPAI.

PMEPA1 Protein Profile

Protein Summary

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with PMEPA1

  • prostate transmembrane protein, androgen induced 1 (Pmepa1)
  • prostate transmembrane protein, androgen induced 1 (PMEPA1)
  • prostate transmembrane protein, androgen induced 1 (pmepa1)
  • transmembrane, prostate androgen induced RNA (tmepai)
  • 2210418I02Rik protein
  • AW455466 protein
  • Erg1.2 protein
  • N4wbp4 protein
  • PMEPA1 protein
  • Stag1 protein
  • tmepai protein
  • zgc:92731 protein

Protein level used designations for PMEPA1

transmembrane prostate androgen-induced protein , transmembrane, prostate androgen induced RNA , prostate transmembrane protein, androgen induced 1 , solid tumor-associated 1 protein , NEDD4 WW domain-binding protein 4 , Nedd4 WW binding protein 4

GENE ID SPECIES
311676 Rattus norvegicus
428166 Gallus gallus
436853 Danio rerio
485945 Canis lupus familiaris
617469 Bos taurus
100137708 Xenopus laevis
100144523 Sus scrofa
56937 Homo sapiens
65112 Mus musculus
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