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Browse our Ubiquitin-Conjugating Enzyme E2I Proteins (UBE2I)

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Ubiquitin-Conjugating Enzyme E2I Proteins (UBE2I)
On www.antibodies-online.com are 40 Ubiquitin-Conjugating Enzyme E2I (UBE2I) Proteins from 13 different suppliers available. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2I Antibodies (119) and Ubiquitin-Conjugating Enzyme E2I Kits (11) and many more products for this protein. A total of 179 Ubiquitin-Conjugating Enzyme E2I products are currently listed.
Synonyms:
5830467E05Rik, C358B7.1, F830028O17Rik, P18, T13J8.70, T13J8_70, ubc9, UbcE2A, Ubce2i, ubce9, ube2ia, UBIQUITIN-PROTEIN LIGASE, ubiquitin conjugating enzyme 9, zUbc9
list all proteins Gene Name GeneID UniProt
UBE2I 7329 P63279
UBE2I 22196 P63280
Rat UBE2I UBE2I 25573 P63281

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Ubiquitin-Conjugating Enzyme E2I Proteins (UBE2I) by Origin

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Top referenced Ubiquitin-Conjugating Enzyme E2I Proteins

  1. Human UBE2I Protein expressed in Escherichia coli (E. coli) - ABIN1047696 : Watanabe, Fujiwara, Kawai, Shimizu, Takami, Hirano, Okuno, Ozaki, Takeda, Shimada, Nagata, Takaichi, Takahashi, Nakamura, Shin: Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle. in Cytogenetics and cell genetics 1996 (PubMed)
    Show all 3 references for ABIN1047696

More Proteins for Ubiquitin-Conjugating Enzyme E2I Interaction Partners

Pig (Porcine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Analysis of protein interactions showed that K179A, K180A, and K221A substitutions of classical swine fever virus core protein disrupt core-SUMO-1 (show SUMO1 Proteins) binding, while K220A substitution precludes core-UBC9 binding.

Caenorhabditis elegans (C. elegans) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. TBX-2 (show TBX2 Proteins) and SUMO-conjugating enzymes are necessary for ABa-derived pharyngeal muscle, and we hypothesize that TBX-2 (show TBX2 Proteins) function requires sumoylation.

Human Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. miR-30e in VSMCs exerted an anti-atherosclerosis effect via inhibiting proliferation and migration, and promoting apoptosis of VSMCs. More specifically, it was demonstrated that miR-30e exhibited these effects on VSMCs partially through targeting Ube2i and downregulating the IkappaBalpha/NFkappaB signaling pathway.

  2. Ubc9 plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase (show BLMH Proteins) and poly(ADP-ribose) polymerase-1 (show PARP1 Proteins). The results are beneficial to deeply understanding of Ubc9 functions and for precise prediction of chemotherapy outcomes in tumors.

  3. Suggest a novel role of PCGF2 (show PCGF2 Proteins) in arsenic trioxide-mediated degradation of PML (show PML Proteins)-RARA (show RARA Proteins) that PCGF2 (show PCGF2 Proteins) might act as a negative regulator of UBE2I via direct interaction.

  4. Akt (show AKT1 Proteins) directly phosphorylates Ubc9 at Thr35 and phosphorylates SUMO1 (show SUMO1 Proteins) at Thr76. Ubc9 phosphorylation at Thr35 promotes Ubc9 thioester bond formation and SUMO1 (show SUMO1 Proteins) phosphorylation at Thr76 stabilizes the SUMO1 (show SUMO1 Proteins) protein.

  5. Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems.

  6. a high-throughput microscopy screen identified ubiquitin carrier protein 9 (Ubc9) as a negative regulator of energy storage in human sc adipocytes. Ubc9 depletion enhanced energy storage and induced the brown fat gene program in human sc adipocytes.

  7. The authors show that ZNF451 is SUMO2 specific and that SUMO modification of ZNF451 may contribute to activity by providing a second molecule of SUMO that interacts with E2.

  8. The RWD domain binds to a Ubc9 surface that also must interact with E1, E3, and SUMO.

  9. These data show that NS5A is a target protein of small ubiquitin-like modifier (SUMO (show SUMO1 Proteins)) and is SUMOylated at lysine residue 348 and silencing of UBC9 impaired hepatitis C virus replication.

  10. SUMO E2 ligase Ubc9 has a critical role in oncogenesis driven by the Ras/Raf (show RAF1 Proteins) pathway

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. The study reveals a function of SUMO protein modification as a Ubiquitin-independent ESCRT sorting signal, regulating the extracellular vesicle release of alpha-Synuclein.

  2. Synaptic trapping of Ubc9 through a PKC phosphorylation-dependent increase of Ubc9 recognition to phosphorylated substrates and consequently leads to the modulation of synaptic sumoylation.

  3. UBC9 has a role in promoting proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis

  4. the sole SUMO E2 enzyme Ubc9 plays a critical role in reprogramming fibroblasts to iPS cells and maintaining ESC pluripotency.

  5. Data indicate that knockdown of ubiquitin-conjugating enzyme 9 (UBC9) by small interfering RNA caused significant accumulations of aggregated protein.

  6. Ubc9 negatively regulates osteoblastic differentiation induced by BMP.

  7. expressed Ubc9 at modestly increased levels showed robust resistance to brain ischemia compared to wild type mice

  8. Ubiquitous loss of sumoylation due to loss of UBC9 led to immediate fatal failure of intestinal function. Sumoylation was required for nucleus positioning and polarized organization of actin in the enterocytes.

  9. FOXL2 (show FOXL2 Proteins) interacts with PIAS1 (show PIAS1 Proteins) and UBC9, and sumoylated in both human and mouse

  10. The temporal profile of UBC9 induction and its ability to affect C/EBPdelta (show CEBPD Proteins) mRNA induction support a role for this protein during early adipogenesis

Zebrafish Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. These data indicate an in vivo requirement of Ubc9 for G2/M transition and/or progression through mitosis during vertebrate organogenesis.

Cow (Bovine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Chromosomal assignment of the bovine ubiquitin-conjugating enzyme E2I (UBE2I ) gene to BTA6q34 defines a new fragment of conserved synteny with human chromosome 16.

Ubiquitin-Conjugating Enzyme E2I (UBE2I) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2I (UBE2I)

  • ubiquitin-conjugating enzyme E2L (UBE2L)
  • ubiquitin-conjugating enzyme E2I (LOC100358924)
  • ubiquitin-conjugating enzyme E2I (UBE2I)
  • Protein UBC-9 (ubc-9)
  • ubiquitin conjugating enzyme 9 (UBC9)
  • ubiquitin-conjugating enzyme E2I (Ube2i)
  • ubiquitin-conjugating enzyme E2I (ube2i)
  • 5830467E05Rik protein
  • C358B7.1 protein
  • F830028O17Rik protein
  • P18 protein
  • T13J8.70 protein
  • T13J8_70 protein
  • ubc9 protein
  • UbcE2A protein
  • Ubce2i protein
  • ubce9 protein
  • ube2ia protein
  • UBIQUITIN-PROTEIN LIGASE protein
  • ubiquitin conjugating enzyme 9 protein
  • zUbc9 protein

Protein level used designations for UBE2I

ubiquitin-conjugating enzyme E2L , ubiquitin-conjugating enzyme E2I , SUMO-conjugating enzyme UBC9 , SUMO-1 conjugating enzyme , ubiquitin conjugating enzyme 9 , ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) , SUMO-1-protein ligase , SUMO-protein ligase , ubiquitin carrier protein 9 , ubiquitin carrier protein I , ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) , ubiquitin-conjugating enzyme UbcE2A , ubiquitin-like protein SUMO-1 conjugating enzyme , ubiquitin-protein ligase E2I , ubiquitin-protein ligase I , Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9) , SUMO-conjugating enzyme UBC9-A , SUMO-protein ligase A , ubc9.1 , ubiquitin carrier protein 9-A , ubiquitin carrier protein I-A , ubiquitin-conjugating enzyme 9 , ubiquitin-conjugating enzyme E2 I-A , ubiquitin-protein ligase I-A , ubiquitin-conjugating enzyme E2I (UBC9 homolog) , ubiquitin-conjugating enzyme E2 I , Ubiquitin carrier protein 9 , Ubiquitin carrier protein I , Ubiquitin-conjugating enzyme E2 I , Ubiquitin-protein ligase I , ubiquitin conjugating enzyme

GENE ID SPECIES
692788 Bombyx mori
100358924 Oryctolagus cuniculus
100533196 Sus scrofa
3565767 Caenorhabditis elegans
828909 Arabidopsis thaliana
7329 Homo sapiens
22196 Mus musculus
25573 Rattus norvegicus
30622 Danio rerio
380450 Xenopus laevis
374123 Gallus gallus
491332 Canis lupus familiaris
515573 Bos taurus
101843247 Mesocricetus auratus
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