Browse our CNTF Proteins (CNTF)

Full name:
Ciliary Neurotrophic Factor Proteins (CNTF)
On are 83 Ciliary Neurotrophic Factor (CNTF) Proteins from 22 different suppliers available. Additionally we are shipping CNTF Antibodies (234) and CNTF Kits (97) and many more products for this protein. A total of 430 CNTF products are currently listed.
list all proteins Gene Name GeneID UniProt
CNTF 25707 P20294
CNTF 1270 P26441
CNTF 12803 P51642

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CNTF Proteins (CNTF) by Origin

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Top referenced CNTF Proteins

  1. Human CNTF Protein expressed in Escherichia coli (E. coli) - ABIN2666952 : Davis, Aldrich, Stahl, Pan, Taga, Kishimoto, Ip, Yancopoulos: LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. in Science (New York, N.Y.) 1993 (PubMed)
    Show all 6 references for 2666952

  2. Human CNTF Protein expressed in Escherichia coli (E. coli) - ABIN2667389 : Garcia, Santafé, Tomàs, Priego, Obis, Lanuza, Besalduch, Tomàs: Exogenous ciliary neurotrophic factor (CNTF) reduces synaptic depression during repetitive stimulation. in Journal of the peripheral nervous system : JPNS 2012 (PubMed)
    Show all 6 references for 2667389

  3. Human CNTF Protein expressed in Escherichia coli (E. coli) - ABIN1046820 : Negro, Tolosano, Skaper, Martini, Callegaro, Silengo, Fiorini, Altruda: Cloning and expression of human ciliary neurotrophic factor. in European journal of biochemistry / FEBS 1991 (PubMed)
    Show all 3 references for 1046820

  4. Rat (Rattus) CNTF Protein expressed in Escherichia coli (E. coli) - ABIN2009024 : Sleeman, Anderson, Lambert, Yancopoulos, Wiegand: The ciliary neurotrophic factor and its receptor, CNTFR alpha. in Pharmaceutica acta Helvetiae 2000 (PubMed)

More Proteins for CNTF Interaction Partners

Human Ciliary Neurotrophic Factor (CNTF) interaction partners

  1. High hydrostatic pressure enables almost 100% refolding of recombinant human ciliary neurotrophic factor from inclusion bodies at high concentration.

  2. CNTFR (show CNTFR PLURAL_@42467@)-specific mutants of CNTF have been developed that bind to the CNTFRalpha (show CNTFR PLURAL_@42467@)-LIFRbeta-gp130 (show IL6ST PLURAL_@42467@) receptor.

  3. Human CNTF expression through lentiviral gene transfer in the rat striatum significantly decreased the levels of neuronal metabolites (N-acetyl-aspartate, N-acetyl-aspartyl-glutamate (show GRIN1 Proteins), and glutamate (show GRIN1 Proteins)).

  4. the biological effects of CNTF on retinoic acid (RA)-predifferentiated SH-SY5Y neuroblastoma (show ARHGEF16 Proteins) cells and the underlying molecular mechanism of this effect were investigated for the first time

  5. R28E mutation in CNTF abrogatesIL-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (show IL6ST Proteins)/ LIFR (show LIFR Proteins).

  6. In this review, CNTF plays an important role in neurogenesis and differentiation of neural stem cells.

  7. The levels of expression and secretion of BDNF and CTNF of induced cells were assessed using immunocytochemical, Real-Time polymerase chain reaction, and enzyme linked immunosorbent assay (ELISA).

  8. CNTF elevated in umbilical cord blood from pre-eclamptic pregnancies

  9. CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor (show EBI3 PLURAL_@42467@) gp130 (show IL6ST PLURAL_@42467@) in Muller glial cells.

  10. Report favourable allelic patterns of ACTN3 (show ACTN3 Proteins) and CNTF genes on aerobic performance in athletes.

Mouse (Murine) Ciliary Neurotrophic Factor (CNTF) interaction partners

  1. data suggest that All-trans retinoic acid administration upregulates CNTF expression in retinal pigment epithelial cells.

  2. Our data reveal that haematopoietic cell-derived CNTF has roles in regulating BM B cell lymphopoiesis and both trabecular and cortical bone, the latter in a sex-dependent manner.

  3. CNTF is upregulated in the corticospinal tract after unilateral pyramidotomy, which likely triggers sprouting of uninjured axons.

  4. Results suggest that slowly up-regulated CNTF in the subventricular zone mediates stroke-induced neurogenesis and is counteracted by inflammation

  5. Ciliary neurotrophic factor activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance

  6. STAT3 (show STAT3 Proteins) can activate CNTF transcription because it bound to its promoter and FAK (show PTK2 Proteins) antagonist-induced CNTF was reduced by blocking STAT3 (show STAT3 Proteins).

  7. data indicate that muscle cells secrete abundant TIMP-1 (show TIMP1 Proteins), MCP-1 (show CPT1B Proteins), and CNTF, and that of these, only CNTF has the ability to suppress osteoblast function and gene expression in a similar manner to myotube-conditioned medium

  8. results suggest that differentiation of distinct types of astrocytes in developing cerebellum may be regulated by ctnf (show TNF Proteins) and bmp2 (show BMP2 Proteins).

  9. Report intravitreal transplantations of modified neural stem cells as cell based delivery system for CNTF in mouse model of photoreceptor degeneration.

  10. CNTF activates hypothalamic urocortin 1-expressing neurons both in vitro and in vivo.

Rabbit Ciliary Neurotrophic Factor (CNTF) interaction partners

  1. High power microwave exposure may cause acute retinal injury and change the expression of CNTF protein in rabbit retina.

CNTF Protein Profile

Protein Summary

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Alternative names and synonyms associated with CNTF

  • ciliary neurotrophic factor (CNTF)
  • ciliary neurotrophic factor (Cntf)
  • ciliary neurotrophic factor (LOC100885759)
  • ciliary neurotrophic factor-like (LOC100518821)
  • ZFP91 zinc finger protein (ZFP91)
  • AI429687 protein
  • CNTF protein
  • GPA protein
  • HCNTF protein

Protein level used designations for CNTF

ciliary neurotrophic factor , ciliary neurotropic factor , growth-promoting activity factor , zinc finger protein 91 homolog

701907 Macaca mulatta
25707 Rattus norvegicus
1270 Homo sapiens
12803 Mus musculus
100009117 Oryctolagus cuniculus
483464 Canis lupus familiaris
100724905 Cavia porcellus
396488 Gallus gallus
100885759 Ovis aries
100518821 Sus scrofa
529006 Bos taurus
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