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Browse our anti-GNAQ (GNAQ) Antibodies

Full name:
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide Antibodies (GNAQ)
On www.antibodies-online.com are 83 Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antibodies from 19 different suppliers available. Additionally we are shipping GNAQ Proteins (13) and GNAQ Kits (1) and many more products for this protein. A total of 106 GNAQ products are currently listed.
Synonyms:
1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, g-alpha-q, Galphaq, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWS

Most Popular Reactivities for anti-GNAQ (GNAQ) Antibodies

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anti-Human GNAQ Antibodies:

anti-Rat (Rattus) GNAQ Antibodies:

anti-Mouse (Murine) GNAQ Antibodies:

All available anti-GNAQ Antibodies

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Top referenced anti-GNAQ Antibodies

  1. Chicken Monoclonal GNAQ Primary Antibody for IF, WB - ABIN968914 : Dutt, Kjoller, Giel, Hall, Toksoz: Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly. in FEBS letters 2002 (PubMed)
    Show all 3 references for ABIN968914

  2. Human Polyclonal GNAQ Primary Antibody for WB - ABIN658100 : Klenke, Tan, Hahn, Mann, Hauner, Manthey, Peters, Siffert, Frey: A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome. in Pharmacogenetics and genomics 2010 (PubMed)
    Show all 2 references for ABIN658100

  3. Human Polyclonal GNAQ Primary Antibody for ELISA, WB - ABIN4315225 : Ngai, Inngjerdingen, Berge, Taskén: Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation. in BMC immunology 2009 (PubMed)

  4. Cow (Bovine) Polyclonal GNAQ Primary Antibody for WB - ABIN2785811 : Arnaud-Lopez, Usala, Ceresini, Mitchell, Pilia, Piras, Sestu, Maschio, Busonero, Albai, Dei, Lai, Mulas, Crisponi, Tanaka, Bandinelli, Guralnik, Loi, Balaci, Sole, Prinzis, Mariotti, Shuldiner, Cao, Schlessinger, Uda, Abecasis, Nagaraja, Sanna, Naitza: Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. in American journal of human genetics 2008 (PubMed)

More Antibodies against GNAQ Interaction Partners

Human Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. Results found that GNAQ was highly expressed in gastric cancer (GC) patient samples and suggest that GNAQ plays a critical role in regulating GC cell growth and survival via canonical oncogenic signaling pathways including MAPK (show MAPK1 Antibodies) and p53 (show TP53 Antibodies).

  2. These findings suggest that Galphaq/11 participates in the sensing/transducing of shear stress independently of GPCR activation in ECs.

  3. CGRP (show S100A12 Antibodies) family of receptors displays both ligand- and RAMP-dependent signaling bias among the Galphas (show GNAS Antibodies), Galphai, and Galphaq/11 pathways.

  4. The Galphas (show GNAS Antibodies) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (show AVPR1A Antibodies), respectively. The beta2-AR/Galphas (show GNAS Antibodies) peptide interface is dominated by electrostatic interactions, whereas the V1AR (show AVPR1A Antibodies)/Galphaq peptide interactions are predominantly hydrophobic.

  5. Data show that GNAQ promotes ARF6 (show ARF6 Antibodies) activation to control the proliferation of Uveal Melanoma Cells.

  6. Driver mutations are rare in mutational hotspots of BRAF (show BRAF Antibodies), NRAS (show NRAS Antibodies), KIT, and GNAQ/GNA11 (show GNA11 Antibodies) in oral mucosal melanoma.

  7. data suggest that the interaction between this novel region in Galphaq and the effector PKCzeta (show PRKCZ Antibodies) is a key event in Galphaq signaling.

  8. The Glu209 GNAQ and GNA11 (show GNA11 Antibodies) missense variants we identified are common in uveal melanoma and have been shown to constitutively activate MAPK (show MAPK1 Antibodies) and/or YAP (show YAP1 Antibodies) signaling. Our data indicate that chorangioma is probably not the placental counterpart of congenital hemangiomas associated with mutations altering Gln209 in GNAQ or GNA11 (show GNA11 Antibodies).

  9. findings demonstrate that hNPS-(1-10) is a biased agonist favoring Galphaq-dependent signaling. It may represent a valuable chemical probe for further investigation of the therapeutic potential of human NPS (show NPS Antibodies) receptor-directed signalingin vivo.

  10. extensive dermal melanocytosis and phakomatosis pigmentovascularis are associated with activating mutations in GNA11 (show GNA11 Antibodies) and GNAQ, genes that encode Galpha (show SUCLG1 Antibodies) subunits of heterotrimeric G proteins

Pig (Porcine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. The Galphas (show GNAS Antibodies) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (show AVPR1A Antibodies), respectively. The beta2-AR/Galphas (show GNAS Antibodies) peptide interface is dominated by electrostatic interactions, whereas the V1AR (show AVPR1A Antibodies)/Galphaq peptide interactions are predominantly hydrophobic.

  2. The phylogenetic trees reveal that porcine Gnaq, is evolutionarily close to the human homolog.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. atomic structure of GRK2 (show ADRBK1 Antibodies) in complex with Galphaq and Gbetagamma, in which the activated Galpha (show SUCLG1 Antibodies) subunit of Gq is fully dissociated from Gbetagamma and dramatically reoriented from its position in the inactive Galphabetagamma heterotrimer [g alphaq]

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. activation of the Gq-membrane-associated estrogen receptors rapidly stimulates hypothalamic paraventricular nucleus CRH (show CRH Antibodies) neurons by suppressing the M-current and potentiating glutamatergic neurotransmission

  2. cell-penetrating peptides should effectively inhibit active Galphaq in cells and that these and genetically encoded sequences may find application as molecular probes, drug leads, and biosensors to monitor the spatiotemporal activation of Galphaq in cells.

  3. The Galphas (show GNAS Antibodies) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (show AVPR1A Antibodies), respectively. The beta2-AR/Galphas (show GNAS Antibodies) peptide interface is dominated by electrostatic interactions, whereas the V1AR (show AVPR1A Antibodies)/Galphaq peptide interactions are predominantly hydrophobic.

  4. the results have identified 138 and 150 ovarian genes that are up-regulated or down-regulated, respectively, at the end of gestation in a Galphaq/11-dependent fashion.

  5. The betaARKrgs peptide, but not endogenous GRK2 (show ADRBK1 Antibodies), interacted with Galpha(q) and interfered with signaling through this G protein. These data support the development of GRK2 (show ADRBK1 Antibodies)-based therapeutic approaches to prevent hypertrophy and heart failure.

  6. Galphaq/Galpha11 signaling pathways play a pivotal role in gene activity patterns during cardiac remodeling.

  7. Developmental AHR activation by pollutants, and other exogenous ligands, increases the likelihood that Gnaq knockout mice will develop autoimmune diseases later in life.

  8. demonstrate that the ability of an MC4R (show MC4R Antibodies) agonist delivered to PVN to inhibit food intake is lost in mice lacking G(q/11)alpha in the paraventricular nucleus of the hypothalamus but not in animals deficient for G(s)alpha

  9. In studies with Gnaq(-/-) mice, Galphaq inhibited the differentiation of Th17 cell via regulating the activity of ERK-1 (show MAPK3 Antibodies)/2 to control the expression of STAT3 (show STAT3 Antibodies) and RORalpha.

  10. the conditional deletion of Galphaq/11 from granulosa/luteal cells prevents the progesterone withdrawal that occurs at the end of pregnancy and impairs parturition.

GNAQ Antigen Profile

Antigen Summary

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.

Alternative names and synonyms associated with GNAQ

  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq) antibody
  • guanine nucleotide binding protein (G protein), q polypeptide (GNAQ) antibody
  • guanine nucleotide binding protein (G protein), q polypeptide (Gnaq) antibody
  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq-b) antibody
  • guanine nucleotide binding protein, alpha q polypeptide (Gnaq) antibody
  • 1110005L02Rik antibody
  • 6230401I02Rik antibody
  • AA408290 antibody
  • AW060788 antibody
  • CMC1 antibody
  • Dsk1 antibody
  • Dsk10 antibody
  • g-alpha-q antibody
  • Galphaq antibody
  • gaq antibody
  • Gnaq antibody
  • gnaqb antibody
  • Gq antibody
  • GqI antibody
  • si:ch73-270f14.2 antibody
  • SWS antibody

Protein level used designations for GNAQ

Galpha q , gnaqa , guanine nucleotide-binding protein G(q) subunit alpha , guanine nucleotide-binding protein alpha-q , G alpha q , guanine nucleotide binding protein alpha q subunit , guanine nucleotide binding protein, alpha q polypeptide , guanine nucleotide regulatory protein G alpha q , heterotrimeric guanine nucleotide-binding protein alpha q subunit , guanine nucleotide-binding protein G(q) alpha subunit

GENE ID SPECIES
570108 Danio rerio
2776 Homo sapiens
403928 Canis lupus familiaris
81666 Rattus norvegicus
427262 Gallus gallus
654405 Sus scrofa
536654 Bos taurus
399261 Xenopus laevis
14682 Mus musculus
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