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Browse our anti-GNAQ (GNAQ) Antibodies

Full name:
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide Antibodies (GNAQ)
On are 81 Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antibodies from 19 different suppliers available. Additionally we are shipping GNAQ Proteins (13) and GNAQ Kits (1) and many more products for this protein. A total of 103 GNAQ products are currently listed.
1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, g-alpha-q, Galphaq, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWS

Most Popular Reactivities for anti-GNAQ (GNAQ) Antibodies

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anti-Human GNAQ Antibodies:

anti-Rat (Rattus) GNAQ Antibodies:

anti-Mouse (Murine) GNAQ Antibodies:

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Top referenced anti-GNAQ Antibodies

  1. Chicken Monoclonal GNAQ Primary Antibody for IF, WB - ABIN968914 : Dutt, Kjoller, Giel, Hall, Toksoz: Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly. in FEBS letters 2002 (PubMed)
    Show all 3 references for ABIN968914

  2. Human Polyclonal GNAQ Primary Antibody for WB - ABIN658100 : Klenke, Tan, Hahn, Mann, Hauner, Manthey, Peters, Siffert, Frey: A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome. in Pharmacogenetics and genomics 2010 (PubMed)
    Show all 2 references for ABIN658100

  3. Dog (Canine) Polyclonal GNAQ Primary Antibody for WB - ABIN2785811 : Arnaud-Lopez, Usala, Ceresini, Mitchell, Pilia, Piras, Sestu, Maschio, Busonero, Albai, Dei, Lai, Mulas, Crisponi, Tanaka, Bandinelli, Guralnik, Loi, Balaci, Sole, Prinzis, Mariotti, Shuldiner, Cao, Schlessinger, Uda, Abecasis, Nagaraja, Sanna, Naitza: Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. in American journal of human genetics 2008 (PubMed)

  4. Human Polyclonal GNAQ Primary Antibody for ELISA, WB - ABIN4315225 : Ngai, Inngjerdingen, Berge, Taskén: Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation. in BMC immunology 2009 (PubMed)

More Antibodies against GNAQ Interaction Partners

Human Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. Driver mutations are rare in mutational hotspots of BRAF (show BRAF Antibodies), NRAS (show NRAS Antibodies), KIT, and GNAQ/GNA11 (show GNA11 Antibodies) in oral mucosal melanoma.

  2. data suggest that the interaction between this novel region in Galphaq and the effector PKCzeta (show PRKCZ Antibodies) is a key event in Galphaq signaling.

  3. The Glu209 GNAQ and GNA11 (show GNA11 Antibodies) missense variants we identified are common in uveal melanoma and have been shown to constitutively activate MAPK (show MAPK1 Antibodies) and/or YAP (show YAP1 Antibodies) signaling. Our data indicate that chorangioma is probably not the placental counterpart of congenital hemangiomas associated with mutations altering Gln209 in GNAQ or GNA11 (show GNA11 Antibodies).

  4. findings demonstrate that hNPS-(1-10) is a biased agonist favoring Galphaq-dependent signaling. It may represent a valuable chemical probe for further investigation of the therapeutic potential of human NPS (show NPS Antibodies) receptor-directed signalingin vivo.

  5. extensive dermal melanocytosis and phakomatosis pigmentovascularis are associated with activating mutations in GNA11 (show GNA11 Antibodies) and GNAQ, genes that encode Galpha (show SUCLG1 Antibodies) subunits of heterotrimeric G proteins

  6. Galphaq expression was negatively associated with interleukin-17A expression in RA patients, indicating that Galphaq ne (show MAPK3 Antibodies)gatively controlled the differentiati (show STAT3 Antibodies)on of Th17 cells.

  7. We conclude that enrichment of GNAQ (R183Q) in port-wine stain (PWS) blood vessels may induce consecutive activation of c-Jun (show JUN Antibodies) N-terminal kinases and extracellular signal regulated kinases, thus contributing to the pathogenesis of PWS.

  8. Distribution of GNAQ and GNA11 (show GNA11 Antibodies) Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.

  9. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 (show RASA1 Antibodies) disorders.

  10. The results suggested that GNAQ mutation induced viability and migration of uveal melanoma cells via Notch (show NOTCH1 Antibodies) signaling activation, which is mediated by YAP (show YAP1 Antibodies) dephosphorylation and nuclear translocation.

Pig (Porcine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. The phylogenetic trees reveal that porcine Gnaq, is evolutionarily close to the human homolog.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. atomic structure of GRK2 (show ADRBK1 Antibodies) in complex with Galphaq and Gbetagamma, in which the activated Galpha (show SUCLG1 Antibodies) subunit of Gq is fully dissociated from Gbetagamma and dramatically reoriented from its position in the inactive Galphabetagamma heterotrimer [g alphaq]

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. the results have identified 138 and 150 ovarian genes that are up-regulated or down-regulated, respectively, at the end of gestation in a Galphaq/11-dependent fashion.

  2. The betaARKrgs peptide, but not endogenous GRK2 (show ADRBK1 Antibodies), interacted with Galpha(q) and interfered with signaling through this G protein. These data support the development of GRK2 (show ADRBK1 Antibodies)-based therapeutic approaches to prevent hypertrophy and heart failure.

  3. Galphaq/Galpha11 signaling pathways play a pivotal role in gene activity patterns during cardiac remodeling.

  4. Developmental AHR activation by pollutants, and other exogenous ligands, increases the likelihood that Gnaq knockout mice will develop autoimmune diseases later in life.

  5. demonstrate that the ability of an MC4R (show MC4R Antibodies) agonist delivered to PVN to inhibit food intake is lost in mice lacking G(q/11)alpha in the paraventricular nucleus of the hypothalamus but not in animals deficient for G(s)alpha

  6. In studies with Gnaq(-/-) mice, Galphaq inhibited the differentiation of Th17 cell via regulating the activity of ERK-1 (show MAPK3 Antibodies)/2 to control the expression of STAT3 (show STAT3 Antibodies) and RORalpha.

  7. the conditional deletion of Galphaq/11 from granulosa/luteal cells prevents the progesterone withdrawal that occurs at the end of pregnancy and impairs parturition.

  8. Gnaq was selectively inactivated in GnRH (show GNRH1 Antibodies) neurons of global Gna11 (show GNA11 Antibodies)--null mice. Galphaq/11-coupled signaling is a major conduit of GnRH (show GNRH1 Antibodies) secretion, results with these mice showed a role for non-Galphaq/11-coupled signaling in reproductive development and function.

  9. Data show that disrupting resistance to inhibitors of cholinesterase 8A (Ric-8A (show RIC8A Antibodies)) expression in hematopoietic cells results in a loss of GTP-binding protein (show DRG1 Antibodies) alpha subunits Galphai2 (show GNAI2 Antibodies), Galphai3 (show GNAI3 Antibodies), and Galphaq.

  10. Data show that the expression of the guanine nucleotide binding protein alpha q GNAQ(Q209L) allele induced causes the rapid development of uveal melanoma, with local invasion of blood vessels and multiple tumors developing in the lungs.

GNAQ Antigen Profile

Antigen Summary

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.

Alternative names and synonyms associated with GNAQ

  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq) antibody
  • guanine nucleotide binding protein (G protein), q polypeptide (GNAQ) antibody
  • guanine nucleotide binding protein (G protein), q polypeptide (Gnaq) antibody
  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq-b) antibody
  • guanine nucleotide binding protein, alpha q polypeptide (Gnaq) antibody
  • 1110005L02Rik antibody
  • 6230401I02Rik antibody
  • AA408290 antibody
  • AW060788 antibody
  • CMC1 antibody
  • Dsk1 antibody
  • Dsk10 antibody
  • g-alpha-q antibody
  • Galphaq antibody
  • gaq antibody
  • Gnaq antibody
  • gnaqb antibody
  • Gq antibody
  • GqI antibody
  • si:ch73-270f14.2 antibody
  • SWS antibody

Protein level used designations for GNAQ

Galpha q , gnaqa , guanine nucleotide-binding protein G(q) subunit alpha , guanine nucleotide-binding protein alpha-q , G alpha q , guanine nucleotide binding protein alpha q subunit , guanine nucleotide binding protein, alpha q polypeptide , guanine nucleotide regulatory protein G alpha q , heterotrimeric guanine nucleotide-binding protein alpha q subunit , guanine nucleotide-binding protein G(q) alpha subunit

570108 Danio rerio
2776 Homo sapiens
403928 Canis lupus familiaris
81666 Rattus norvegicus
427262 Gallus gallus
654405 Sus scrofa
536654 Bos taurus
399261 Xenopus laevis
14682 Mus musculus
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