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Placental expression of HTR7 was significantly increased in women with pre-eclampsia compared to controls.
PTP1B (show PTPN1 Antibodies) directly regulates STAT5 (show STAT5A Antibodies) phosphorylation and its activation via the cAMP/PKA pathway downstream of the 5-HT7 receptor is involved in the suppression of beta-casein (show CSN2 Antibodies) expression in MCF-12A cells
Study shows that HTR7 variants are not related to the overall improvement in schizophrenia symptoms following perospirone or aripiprazole treatment
Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1 (show GPRASP1 Antibodies)
This is a review of literature about how 5-HT7 receptor has been implicated in cognitive disturbances, sleep and circadian rhythmicity disorders, anxiety and depression
Genetic variations in HTR7 serotonin receptor (show HTR1B Antibodies) contribute to the predisposition for alcohol dependence.
There is a cross-reactivity between 5-HT7 and 5-HT1A (show HTR1A Antibodies) receptors and in this review they are shown to have a role in depressive disorders.
Serotonin skews human macrophage polarization through HTR2B (show HTR2B Antibodies) and HTR7.
the expression of 5-HT7 receptors in brain tissues was higher in the epilepsy group compared with the nonepileptic group; the results suggested that 5-HT7 receptors participate in the pathogenesis of temporal lobe epilepsy
The interaction between RhoBTB3 (show RHOBTB3 Antibodies) and the 5-HT7a receptor strongly inhibits proteasomal degradation of the 5-HT7a receptor.
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.
, 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
, 5-hydroxytryptamine receptor 7
, high affinity serotonin receptor (5HT7)
, serotonin receptor 7