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Browse our IFNAR1 Proteins (IFNAR1)

Full name:
Interferon (Alpha, beta and Omega) Receptor 1 Proteins (IFNAR1)
On are 21 Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Proteins from 8 different suppliers available. Additionally we are shipping IFNAR1 Antibodies (164) and IFNAR1 Kits (6) and many more products for this protein. A total of 207 IFNAR1 products are currently listed.
AVP, CD118, Ifar, IFN-alpha-REC, IFN-R-1, IFNAR, IFNAR1, IFNBR, IFRC, Infar
list all proteins Gene Name GeneID UniProt
IFNAR1 15975 P33896
IFNAR1 3454 P17181
IFNAR1 288264  

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IFNAR1 Proteins (IFNAR1) by Origin

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Top referenced IFNAR1 Proteins

  1. Cynomolgus IFNAR1 Protein expressed in Human Cells - ABIN2009874 : Abramovich, Ratovitski, Lundgren, Revel: Identification of mRNAs encoding two different soluble forms of the human interferon alpha-receptor. in FEBS letters 1994 (PubMed)
    Show all 4 references for ABIN2009874

  2. Human IFNAR1 Protein expressed in Human Cells - ABIN2005569 : Colamonici, Yan, Domanski, Handa, Smalley, Mullersman, Witte, Krishnan, Krolewski: Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase. in Molecular and cellular biology 1994 (PubMed)
    Show all 4 references for ABIN2005569

  3. Mouse (Murine) IFNAR1 Protein expressed in Human Cells - ABIN2007842 : Gauci, Helbig, Slijper, Krijgsveld, Heck, Mohammed: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. in Analytical chemistry 2009 (PubMed)
    Show all 4 references for ABIN2007842

  4. Human IFNAR1 Protein expressed in HEK-293 Cells - ABIN2181250 : Li, Leung, Kerr, Stark: Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling. in Molecular and cellular biology 1997 (PubMed)
    Show all 3 references for ABIN2181250

More Proteins for IFNAR1 Interaction Partners

Mouse (Murine) Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. Data show that both NF-kappaB (NF-kappaB (show NFKB1 Proteins)) and tonic interferon (show IFNA Proteins) signals are involved in the final maturation of thymocytes into naive T cells.

  2. ablation of Ifnar1 partially protected mice from caerulein-induced pancreatitis, as demonstrated by reduced tissue damage and macrophage recruitment.

  3. IFNAR signaling directly modulates T lymphocyte activity, resulting in milder experimental autoimmune encephalomyelitis development

  4. whole-body or pancreas-specific Perk (show EIF2AK3 Proteins) ablation in mice leads to an increase in IFNAR1 protein levels and signaling in pancreatic tissues.

  5. IFN-I receptor 1 deficient mice (IFNAR1(-/-)) displayed significantly attenuated poly I:C-induced hypothermia, hypoactivity and weight loss compared to WT C57BL/6 mice.

  6. Data suggest MyD88 (show MYD88 Proteins) (myeloid differentiation primary response (show GADD45B Proteins) protein) is redundant for Ifnar1/IFN-I (interferon (show IFNA Proteins) type I) responses and overall defense/innate immunity against systemic mouse Cytomegalovirus infection; this is consistent with human data.

  7. IFNAR1 signaling in microglia is essential for ischemic preconditioning in white matter.

  8. Lack of IFNB (show IFNB1 Proteins) or IFNAR was associated with reduced neurogenesis in the hippocampus; dentate gyrus

  9. IFN-alpha (show IFNA Proteins)/beta is able to drive the formation of a Stat2 (show STAT2 Proteins) and IRF-9 (show IRF9 Proteins) complex that drives the expression of a subset of IFN-stimulated genes, but with substantially delayed kinetics.

  10. TNFR1 (show TNFRSF1A Proteins)- and IFNAR1-deficient mice showed partial protection toward Aldara-induced inflammation compared with control groups. Double knockout mice lacking both receptors showed superior protection to Aldara in comparison with the single knockout mice.

Human Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. data illustrate a lipid G-protein coupled receptor (GPCR (show TAS1R3 Proteins))-IFNAR1 regulatory loop that balances effective and detrimental immune responses and elevated endogenous S1PR1 (show S1PR1 Proteins) signaling

  2. Data suggest IFNA2 (interferon (show IFNA Proteins), alpha 2) binding to extracellular domain of IFNAR1 or IFNAR2 (show IFNAR2 Proteins) promotes proximity between intracellular domains; signaling depends on duration of activation/affinity of binding rather than specific conformational changes.

  3. These findings suggest that influenza A virus hemagglutinin (show HA Proteins) causes IFNAR1 degradation, which in turn helps the virus escape the powerful innate immune system.

  4. Prolidase (show PEPD Proteins) was required for IFNAR1 maturation and accumulation, activation of IFNbeta-stimulated gene induction, and IFN-I-dependent viral control.

  5. IFNL4 and IFNL3 (show IL28B Proteins) associated polymorphisms strongly influence the spontaneous IFN-alpha (show IFNA Proteins) receptor-1 expression in HCV-infected patients

  6. The expression of IFNAR1, IFNgammaR1 and ribovarin transporters were significantly impaired in chronic liver disease and cirrhotic livers.

  7. Results show that SNPs in IFNAR1 and IFNG (show IFNG Proteins) were risk factors for malaria in Indian population.

  8. sequence variants of both the IFNAR1-17470 and IL-10 (show IL10 Proteins)-592 genes were correlated with susceptibility to chronic hepatitis B.

  9. Dimerization of IFNAR1 and IFNAR2 (show IFNAR2 Proteins) and the limiting role of IFNAR1 binding affinity in complex assembly is modulated by USP18 (show USP18 Proteins).

  10. Therefore, this study associated, for the first time, in a large panel of pancreatic cancer cell lines the effects of IFN-alpha (show IFNA Proteins)/-beta with the expression of type-I IFN receptors.

Cow (Bovine) Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 (show IFNA2 Proteins) generates type I IFN competitive antagonists.

Pig (Porcine) Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. The complete 168,835 bp insert sequence of a porcine BAC clone harboring the IFNAR1 gene was determined.

IFNAR1 Protein Profile

Protein Summary

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Alternative names and synonyms associated with IFNAR1

  • interferon (alpha, beta and omega) receptor 1 (IFNAR1)
  • interferon-alpha/beta receptor alpha chain-like (ifnar1)
  • interferon receptor 1 (IFNAR1)
  • interferon (alpha, beta and omega) receptor 1 (LOC100230358)
  • interferon (alpha and beta) receptor 1 (Ifnar1)
  • interferon (alpha, beta and omega) receptor 1 (Ifnar1)
  • type I interferon receptor 1e (IFNAR1E)
  • AVP protein
  • CD118 protein
  • Ifar protein
  • IFN-alpha-REC protein
  • IFN-R-1 protein
  • IFNAR protein
  • IFNAR1 protein
  • IFNBR protein
  • IFRC protein
  • Infar protein

Protein level used designations for IFNAR1

interferon alpha/beta receptor 1 , interferon receptor , soluble receptor , interferon-alpha receptor 1 , putative interferon-alpha/beta receptor alpha chain , interferon receptor 1 , interferon (alpha, beta and omega) receptor 1 , interferon alpha/beta receptor 1-like , IFN-R-1 , IFN-alpha/beta receptor 1 , IFN-alpha/betaR , INF-a receptor , interferon-alpha/beta receptor 1 , type I interferon receptor 1 , CRF2-1 , alpha-type antiviral protein , beta-type antiviral protein , cytokine receptor class-II member 1 , cytokine receptor family 2 member 1 , interferon-alpha/beta receptor alpha chain , interferon-beta receptor 1 , interferon (alpha and beta) receptor 1 , IFN-alpha-REC , interferon, alpha; receptor , Interferon-alpha/beta receptor alpha chain

395665 Gallus gallus
458516 Pan troglodytes
699604 Macaca mulatta
100136116 Oncorhynchus mykiss
100137245 Papio anubis
100410306 Callithrix jacchus
100443118 Pongo abelii
100583382 Nomascus leucogenys
100230358 Taeniopygia guttata
15975 Mus musculus
3454 Homo sapiens
288264 Rattus norvegicus
609830 Canis lupus familiaris
282257 Bos taurus
396658 Sus scrofa
100715784 Cavia porcellus
443126 Ovis aries
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