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Browse our IFNAR1 Proteins (IFNAR1)

Full name:
Interferon (Alpha, beta and Omega) Receptor 1 Proteins (IFNAR1)
On are 22 Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Proteins from 9 different suppliers available. Additionally we are shipping IFNAR1 Antibodies (185) and IFNAR1 Kits (10) and many more products for this protein. A total of 234 IFNAR1 products are currently listed.
AVP, CD118, Ifar, IFN-alpha-REC, IFN-R-1, IFNAR, IFNAR1, IFNBR, IFRC, Infar
list all proteins Gene Name GeneID UniProt
IFNAR1 15975 P33896
IFNAR1 3454 P17181
IFNAR1 288264  

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IFNAR1 Proteins (IFNAR1) by Origin

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Top referenced IFNAR1 Proteins

  1. Mouse (Murine) IFNAR1 Protein expressed in Human Cells - ABIN2007842 : Abramovich, Ratovitski, Lundgren, Revel: Identification of mRNAs encoding two different soluble forms of the human interferon alpha-receptor. in FEBS letters 1994 (PubMed)
    Show all 4 references for ABIN2007842

  2. Human IFNAR1 Protein expressed in Human Cells - ABIN2005569 : Colamonici, Yan, Domanski, Handa, Smalley, Mullersman, Witte, Krishnan, Krolewski: Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase. in Molecular and cellular biology 1994 (PubMed)
    Show all 4 references for ABIN2005569

  3. Rhesus Monkey IFNAR1 Protein expressed in Human Cells - ABIN2009876 : Gauci, Helbig, Slijper, Krijgsveld, Heck, Mohammed: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. in Analytical chemistry 2009 (PubMed)
    Show all 4 references for ABIN2009876

  4. Human IFNAR1 Protein expressed in HEK-293 Cells - ABIN2181250 : Li, Leung, Kerr, Stark: Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling. in Molecular and cellular biology 1997 (PubMed)
    Show all 3 references for ABIN2181250

More Proteins for IFNAR1 Interaction Partners

Mouse (Murine) Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. These results identify a key interface created by IFNAR1 residues Tyr (show TYR Proteins)(240) and Tyr (show TYR Proteins)(274) interacting with IFN-beta (show IFNB1 Proteins) residues Phe(63), Leu(64), Glu (show GCG Proteins)(77), Thr (show TRH Proteins)(78), Val(81), and Arg(82) that underlie IFN-beta (show IFNB1 Proteins)-IFNAR1-mediated signaling and biological processes.

  2. IFNAR1-deficiency accelerated humoral immune responses and parasite control by boosting ICOS (show ICOS Proteins)-signalling in two non-lethal murine models of malaria

  3. reduced type I interferon (show IFNA Proteins) production in obesity is caused by SOCS3 (show SOCS3 Proteins) overexpression as well as tolerance induced by leptin (show LEP Proteins)

  4. Downregulation of IFNAR1 promotes melanoma development and progression. IFNAR1 mutation, which is partially resistant to downregulation, delays melanoma development.

  5. The study provides evidence for the importance of brain endothelial and epithelial cells in the communication between the Central Nervous System and the immune system, and demonstrates tissue specific IFNAR1 engagement during sickness behavior.

  6. Data show that both NF-kappaB (NF-kappaB (show NFKB1 Proteins)) and tonic interferon (show IFNA Proteins) signals are involved in the final maturation of thymocytes into naive T cells.

  7. ablation of Ifnar1 partially protected mice from caerulein-induced pancreatitis, as demonstrated by reduced tissue damage and macrophage recruitment.

  8. IFNAR signaling directly modulates T lymphocyte activity, resulting in milder experimental autoimmune encephalomyelitis development

  9. whole-body or pancreas-specific Perk (show EIF2AK3 Proteins) ablation in mice leads to an increase in IFNAR1 protein levels and signaling in pancreatic tissues.

  10. IFN-I receptor 1 deficient mice (IFNAR1(-/-)) displayed significantly attenuated poly I:C-induced hypothermia, hypoactivity and weight loss compared to WT C57BL/6 mice.

Human Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. Downregulation of IFNAR1 in tumor stroma stimulated colorectal cancer development and growth, played a key role in formation of the immune-privileged niche.

  2. These results suggest that miR-29a, upregulated during RSV infection, is a negative regulator of IFNAR1 and is critical for respiratory syncytial virus NS1-induced virus replication.

  3. On one hand, hepatitis B virus activates MMP-9 (show MMP9 Proteins) in infected patients and leukocytes. On the other hand, MMP-9 (show MMP9 Proteins) facilitates hepatitis B virus replication through repressing IFN/JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling, IFNAR1 function, and IFN-alpha (show IFNA Proteins) action.

  4. this study shows that single nucleotide polymorphism in IFNAR1 gene is associated with female vitiligo (show MITF Proteins) in Estonian patients

  5. A small proportion of both pancreatic and periampullary tumors showed a strong expression of the IFNAR-1.

  6. rs2843710 of IFNAR1 was associated with the susceptibility and severity of EV71 HFMD in Chinese Han populations.

  7. Genetic polymorphisms of the promoter of INFAR gene represent important factors associated with the clinical phase of HBeAg-negative chronic HBV infection.

  8. data illustrate a lipid G-protein coupled receptor (GPCR (show TAS1R3 Proteins))-IFNAR1 regulatory loop that balances effective and detrimental immune responses and elevated endogenous S1PR1 (show S1PR1 Proteins) signaling

  9. Data suggest IFNA2 (interferon (show IFNA Proteins), alpha 2) binding to extracellular domain of IFNAR1 or IFNAR2 (show IFNAR2 Proteins) promotes proximity between intracellular domains; signaling depends on duration of activation/affinity of binding rather than specific conformational changes.

  10. These findings suggest that influenza A virus hemagglutinin (show HA Proteins) causes IFNAR1 degradation, which in turn helps the virus escape the powerful innate immune system.

Cow (Bovine) Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 (show IFNA2 Proteins) generates type I IFN competitive antagonists.

Pig (Porcine) Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) interaction partners

  1. The complete 168,835 bp insert sequence of a porcine BAC clone harboring the IFNAR1 gene was determined.

IFNAR1 Protein Profile

Protein Summary

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Alternative names and synonyms associated with IFNAR1

  • interferon (alpha, beta and omega) receptor 1 (IFNAR1)
  • interferon-alpha/beta receptor alpha chain-like (ifnar1)
  • interferon receptor 1 (IFNAR1)
  • interferon (alpha, beta and omega) receptor 1 (LOC100230358)
  • interferon (alpha and beta) receptor 1 (Ifnar1)
  • interferon (alpha, beta and omega) receptor 1 (Ifnar1)
  • type I interferon receptor 1e (IFNAR1E)
  • AVP protein
  • CD118 protein
  • Ifar protein
  • IFN-alpha-REC protein
  • IFN-R-1 protein
  • IFNAR protein
  • IFNAR1 protein
  • IFNBR protein
  • IFRC protein
  • Infar protein

Protein level used designations for IFNAR1

interferon alpha/beta receptor 1 , interferon receptor , soluble receptor , interferon-alpha receptor 1 , putative interferon-alpha/beta receptor alpha chain , interferon receptor 1 , interferon (alpha, beta and omega) receptor 1 , interferon alpha/beta receptor 1-like , IFN-R-1 , IFN-alpha/beta receptor 1 , IFN-alpha/betaR , INF-a receptor , interferon-alpha/beta receptor 1 , type I interferon receptor 1 , CRF2-1 , alpha-type antiviral protein , beta-type antiviral protein , cytokine receptor class-II member 1 , cytokine receptor family 2 member 1 , interferon-alpha/beta receptor alpha chain , interferon-beta receptor 1 , interferon (alpha and beta) receptor 1 , IFN-alpha-REC , interferon, alpha; receptor , Interferon-alpha/beta receptor alpha chain

395665 Gallus gallus
458516 Pan troglodytes
699604 Macaca mulatta
100136116 Oncorhynchus mykiss
100137245 Papio anubis
100410306 Callithrix jacchus
100443118 Pongo abelii
100583382 Nomascus leucogenys
100230358 Taeniopygia guttata
15975 Mus musculus
3454 Homo sapiens
288264 Rattus norvegicus
609830 Canis lupus familiaris
282257 Bos taurus
396658 Sus scrofa
100715784 Cavia porcellus
443126 Ovis aries
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