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anti-Human IL-13 Antibodies:
anti-Mouse (Murine) IL-13 Antibodies:
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Human Monoclonal IL-13 Primary Antibody for ELISA (Capture), ELISpot - ABIN281656
Raz, Elias, Avron, Tamir, Metzger, Cohen: Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. in Lancet (London, England) 2001
Show all 2 references for ABIN281656
Human Monoclonal IL-13 Primary Antibody for ELISPOT (Capture), Neut - ABIN282537
van Halteren, van Etten, de Jong, Bouillon, Roep, Mathieu: Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3). in Diabetes 2002
Show all 2 references for ABIN282537
Pig (Porcine) Polyclonal IL-13 Primary Antibody for EIA, WB - ABIN401064
Trigona, Brown, Estes: Functional implications for signaling via the IL4R/IL13R complex on bovine cells. in Veterinary immunology and immunopathology 2000
Mouse (Murine) Monoclonal IL-13 Primary Antibody for Neut - ABIN282535
Park, Chen, Esmaeil, Lucas, Marsh, Reibman, Grunig: Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution. in Pulmonary circulation 2015
Data show that single nucleotide polymorphisms (SNPs) rs848 in the interleukin 13 (IL13) gene region is significantly associated with a continuous measure of symptom severity in adult subjects with ever asthma.
Lack of association between RAD50-IL13 polymorphisms and pediatric asthma susceptibility in Northeastern Han Chinese
These in vitro data imply that IL-13-treated skin equivalent model exhibited atopic dermatitis-like features and that IL-13 may have a role in basement membrane defects.
IL-13 is a type 2 cytokine that is a key mediator of airway inflammation and remodeling in many inflammatory diseases of the lung, such as asthma. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201506-1243OC#.V2bnHdLrtNs
analysis of how expression of Th2 cytokines, especially IL-4 (show IL4 Antibodies) and IL-13, are regulated in Th2 cells [review]
review of IL-4 (show IL4 Antibodies) and IL-13 mast cell immunity and detail of the differences that exist between mouse and human mast cell responses to IL-4 (show IL4 Antibodies) and IL-13 [review]
description of differential expression and non-canonical regulation of IL-4 (show IL4 Antibodies) and IL-13 in various immune cells [review]
review of the roles IL-4 (show IL4 Antibodies) and IL-13 play in allergic inflammatory states and the utility of their modulation as potential therapeutic strategies for the treatment of allergic disorders [review]
The IL13 haplotype rs1800925T-rs20541C increased the risk of disease progression to late-stage schistosomiasis, whereas haplotype rs1800925C-rs20541A showed a protective role against development of late-stage schistosomiasis.
IL-13 induces miR (show MLXIP Antibodies)-142-5p and downregulates miR (show MLXIP Antibodies)-130a-3p in macrophages, regulating macrophage profibrogenic gene expression in chronic inflammation.
Placenta growth factor (show PGF Antibodies) augments airway hyperresponsiveness via leukotrienes and IL-13.
Natural helper cells contribute to pulmonary eosinophilia by producing IL-13 via IL-33/ST2 pathway in a murine model of respiratory syncytial virus infection
Data (including data from studies in knockout/transgenic mice) suggest T cell-derived IL4/IL13 are required for immunologic memory and IgE response to helminth Nippostrongylus brasiliensis but are not required for expansion/proliferation of B cells.
Curcumin up-regulates mRNA and protein levels of IL-4 (show IL4 Antibodies) and IL-13
These data indicate that distal airways might be less sensitive to IL-13-induced GC metaplasia and mucus production through lower expression of IL-13Ralpha1 and attenuated activation of downstream signalling.
IL-4 (show IL4 Antibodies) and IL-13 have a critical role in innate immune cells for protective immunity against gastrointestinal helminths.
These data demonstrate that dysregulated IL-25 (show IL25 Antibodies) expression contributes to lipid accumulation, whereas exogenous IL-25 (show IL25 Antibodies) protects against hepatic steatosis through IL-13 activation of STAT6 (show STAT6 Antibodies).
TH2 cells and their cytokines IL-4 (show IL4 Antibodies) and IL-13 regulate formation and function of lymphatic vessels.
T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (show MMP1 Antibodies) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
, T-cell activation protein P600