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anti-Human IL-13 Antibodies:
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Human Monoclonal IL-13 Primary Antibody for ELISA (Capture), ELISpot - ABIN281656
Raz, Elias, Avron, Tamir, Metzger, Cohen: Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial. in Lancet (London, England) 2001
Show all 2 references for ABIN281656
Human Monoclonal IL-13 Primary Antibody for ELISPOT (Capture), Neut - ABIN282537
van Halteren, van Etten, de Jong, Bouillon, Roep, Mathieu: Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3). in Diabetes 2002
Show all 2 references for ABIN282537
Pig (Porcine) Polyclonal IL-13 Primary Antibody for EIA, WB - ABIN401064
Trigona, Brown, Estes: Functional implications for signaling via the IL4R/IL13R complex on bovine cells. in Veterinary immunology and immunopathology 2000
Mouse (Murine) Monoclonal IL-13 Primary Antibody for Neut - ABIN282535
Park, Chen, Esmaeil, Lucas, Marsh, Reibman, Grunig: Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution. in Pulmonary circulation 2015
a protective role of mutant alleles G and A in IL-10 (show IL10 Antibodies)-1082A/G and IL-13+2044G/A against gliomas.
We show that polymorphisms in IL8 (show IL8 Antibodies) rs1126647 and IL13 rs1800925 are associated with sunitinib-induced toxicities.
Data show that single nucleotide polymorphisms (SNPs) rs848 in the interleukin 13 (IL13) gene region is significantly associated with a continuous measure of symptom severity in adult subjects with ever asthma.
Lack of association between RAD50-IL13 polymorphisms and pediatric asthma susceptibility in Northeastern Han Chinese
These in vitro data imply that IL-13-treated skin equivalent model exhibited atopic dermatitis-like features and that IL-13 may have a role in basement membrane defects.
IL-13 is a type 2 cytokine that is a key mediator of airway inflammation and remodeling in many inflammatory diseases of the lung, such as asthma. Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201506-1243OC#.V2bnHdLrtNs
analysis of how expression of Th2 cytokines, especially IL-4 (show IL4 Antibodies) and IL-13, are regulated in Th2 cells [review]
review of IL-4 (show IL4 Antibodies) and IL-13 mast cell immunity and detail of the differences that exist between mouse and human mast cell responses to IL-4 (show IL4 Antibodies) and IL-13 [review]
description of differential expression and non-canonical regulation of IL-4 (show IL4 Antibodies) and IL-13 in various immune cells [review]
review of the roles IL-4 (show IL4 Antibodies) and IL-13 play in allergic inflammatory states and the utility of their modulation as potential therapeutic strategies for the treatment of allergic disorders [review]
IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy.
Placenta growth factor (show PGF Antibodies) augments airway hyperresponsiveness via leukotrienes and IL-13.
Natural helper cells contribute to pulmonary eosinophilia by producing IL-13 via IL-33/ST2 pathway in a murine model of respiratory syncytial virus infection
Data (including data from studies in knockout/transgenic mice) suggest T cell-derived IL4/IL13 are required for immunologic memory and IgE response to helminth Nippostrongylus brasiliensis but are not required for expansion/proliferation of B cells.
Curcumin up-regulates mRNA and protein levels of IL-4 (show IL4 Antibodies) and IL-13
These data indicate that distal airways might be less sensitive to IL-13-induced GC metaplasia and mucus production through lower expression of IL-13Ralpha1 and attenuated activation of downstream signalling.
IL-13 induces miR (show MLXIP Antibodies)-142-5p and downregulates miR (show MLXIP Antibodies)-130a-3p in macrophages, regulating macrophage profibrogenic gene expression in chronic inflammation.
IL-4 (show IL4 Antibodies) and IL-13 have a critical role in innate immune cells for protective immunity against gastrointestinal helminths.
These data demonstrate that dysregulated IL-25 (show IL25 Antibodies) expression contributes to lipid accumulation, whereas exogenous IL-25 (show IL25 Antibodies) protects against hepatic steatosis through IL-13 activation of STAT6 (show STAT6 Antibodies).
T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (show MMP1 Antibodies) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
, T-cell activation protein P600