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IL-13 antibody (AA 118-146)

IL13 Reactivity: Human IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031449
$578.58
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  • Target See all IL-13 (IL13) Antibodies
    IL-13 (IL13) (Interleukin 13 (IL13))
    Binding Specificity
    • 15
    • 11
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 118-146
    Reactivity
    • 95
    • 39
    • 29
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 77
    • 31
    • 27
    • 3
    • 2
    Rabbit
    Clonality
    • 82
    • 58
    Polyclonal
    Conjugate
    • 86
    • 20
    • 8
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-13 antibody is un-conjugated
    Application
    • 80
    • 75
    • 32
    • 20
    • 18
    • 14
    • 13
    • 13
    • 10
    • 10
    • 10
    • 9
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the IL-13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    IL-13 (IL13) (Interleukin 13 (IL13))
    Alternative Name
    IL-13 (IL13 Products)
    Synonyms
    IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
    Background
    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].
    UniProt
    P35225
    Pathways
    JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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