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Browse our anti-IL12RB1 (IL12RB1) Antibodies

Full name:
anti-Interleukin 12 Receptor beta 1 Antibodies (IL12RB1)
On www.antibodies-online.com are 73 Interleukin 12 Receptor beta 1 (IL12RB1) Antibodies from 15 different suppliers available. Additionally we are shipping IL12RB1 Proteins (15) and IL12RB1 Kits (7) and many more products for this protein. A total of 104 IL12RB1 products are currently listed.
Synonyms:
CD212, IL-12R, IL-12R-BETA1, IL-12R[b], IL12RB, IL12RB1
list all antibodies Gene Name GeneID UniProt
IL12RB1 171333  
IL12RB1 3594 P42701
IL12RB1 16161 Q60837

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Most Popular Reactivities for anti-IL12RB1 (IL12RB1) Antibodies

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anti-Rat (Rattus) IL12RB1 Antibodies:

anti-Human IL12RB1 Antibodies:

anti-Mouse (Murine) IL12RB1 Antibodies:

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Top referenced anti-IL12RB1 Antibodies

  1. Mouse (Murine) Monoclonal IL12RB1 Primary Antibody for FACS - ABIN2689093 : Chua, Wilkinson, Presky, Gubler: Cloning and characterization of a mouse IL-12 receptor-beta component. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 8 references for ABIN2689093

  2. Human Monoclonal IL12RB1 Primary Antibody for FACS - ABIN1449166 : Nagayama, Sato, Kawasaki, Enomoto, Morimoto, Tadokoro, Juji, Asano, Takahashi: IL-12 responsiveness and expression of IL-12 receptor in human peripheral blood monocyte-derived dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 2 references for ABIN1449166

  3. Human Monoclonal IL12RB1 Primary Antibody for FACS - ABIN1449167 : Kawashima, Kawasaki, Kitamura, Nojima, Morimoto: Interleukin-12 induces tyrosine phosphorylation of an 85-kDa protein associated with the interleukin-12 receptor beta 1 subunit. in Cellular immunology 1998 (PubMed)
    Show all 2 references for ABIN1449167

  4. Mouse (Murine) Polyclonal IL12RB1 Primary Antibody for IHC (fro), IF (p) - ABIN747863 : Terayama, Yoshimoto, Hirai, Naito, Qu, Hatayama, Hayashi, Mitobe, Furusawa, Mizoguchi, Kezuka, Goto, Suyama, Moriyama, Sakabe, Itoh: Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege. in PLoS ONE 2014 (PubMed)

  5. Human Polyclonal IL12RB1 Primary Antibody for EIA, WB - ABIN498037 : Namkung, Lee, Kim, Kim, Kim, Shin, Cho, Yang: Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans. in Journal of dermatological science 2010 (PubMed)

More Antibodies against IL12RB1 Interaction Partners

Cow (Bovine) Interleukin 12 Receptor beta 1 (IL12RB1) interaction partners

  1. Four SNPs in IFNGR2 (show IFNGR2 Antibodies), IL12RB1, IL12RB2 (show IL12RB2 Antibodies), and IL23R (show IL23R Antibodies) were found to be associated with the MAP infection status of the resource population.

Human Interleukin 12 Receptor beta 1 (IL12RB1) interaction partners

  1. Truncated IL12rbeta1/Fc is a novel fusion protein for specific binding multiple forms of p40 subunit to exert potent anti-inflammatory effects.

  2. the introduction of RNA-DNA differences into an individual's IL12RB1 mRNA repertoire is a novel determinant of IL12 (show IL12A Antibodies)/23 sensitivity.

  3. we describe cosegregation of a heterozygous germline defect in IL12RB1 and gastric cancer development in a family with IL-12Rbeta1 deficiency

  4. individual variability in IL12RB1 function is introduced at the epigenetic, genomic polymorphism, and mRNA splicing levels [review]

  5. Early coupled up-regulation of IL12RB1 in CD8 (show CD8A Antibodies)+ central memory and effector T cells result in better clinical outcomes in liver transplant recipients.

  6. Genetic variations of IL-12B (show IL12B Antibodies), IL-12Rbeta1, IL-12Rbeta2 in Behcet's disease and VKH syndrome.

  7. The IL-23 (show IL23A Antibodies)/IL-23R (show IL23R Antibodies)/IL-12Rbeta1 complex formation does not follow the classical "site I-II-III" architectural paradigm.

  8. SNP rs2305743 in IL12RB1 was associated with systemic sclerosis.

  9. A review of the molecular genetics of all known IL12RB1 mutations and variants.

  10. IL12Rbeta1 expression is lacking on CD8 (show CD8A Antibodies)+ T and natural killer (NK) cell surface in a 33-year-old patient with Mycobacterium tilburgii infection.

Mouse (Murine) Interleukin 12 Receptor beta 1 (IL12RB1) interaction partners

  1. the data support a model wherein IL12Rbeta1DeltaTM is a secreted product of il12rb1 that promotes resistance to M. tuberculosis infection by potentiating T(H) cells response to IL-12 (show IL12A Antibodies).

  2. Although they share a common subunit, IL-23 (show IL23A Antibodies) and IL-12 (show IL12A Antibodies) receptors are not expressed on the same cell populations.

  3. IL12RB1 is essential for human resistance to Mycobacterium tuberculosis infection

  4. IL-12p40 is induced rapidly in response to Francisella tularensis LVS and is required for DC migration through an IL-12Rbeta1-IL-12(p40 (show IL12B Antibodies))2 dependent mechanism.

  5. IL-12Rbeta1DeltaTM represents a novel regulator of IL12Rbeta1-dependent dendritic cell function and of the immune response to Mycobacterium tuberculosis.

  6. IL-12R beta 1 deficiency results in decreased viral replication and inflammation following coxsackievirus B3-induced myocarditis, decreasing IL-1 beta (show IL1B Antibodies) and IL-18 (show IL18 Antibodies) in the heart.

  7. The binding domain in the IL-12 receptor beta 1 cytoplasmic region has been mapped to sphingosine kinase 2 (show SPHK2 Antibodies).

  8. Expression of the IL-12 (show IL12A Antibodies) beta 1 receptor is upregulated in both microglia and splenic macrophages.

  9. IL-12 receptor beta 1 subunit plays an essential role in the activation and differentiation of Th1 (show HAND1 Antibodies)-type myelin oligodendrocyte glycoprotein (MOG (show MOG Antibodies))-specific autoreactive T cells in vivo.

  10. IL-12 receptor beta 1 (Rbeta1) mediates IL-12 p40 (show IL12B Antibodies) homodimer (p80 (show COIL Antibodies))-dependent macrophage chemotaxis and inhibition of the p80 (show COIL Antibodies)-Rbeta1 interaction, a novel anti-inflammatory strategy to manipulate inflammation associated with respiratory viral infection.

IL12RB1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with IL12RB1

  • interleukin 12 receptor, beta 1 (Il12rb1) antibody
  • interleukin 12 receptor, beta 1 (IL12RB1) antibody
  • CD212 antibody
  • IL-12R antibody
  • IL-12R-BETA1 antibody
  • IL-12R[b] antibody
  • IL12RB antibody
  • IL12RB1 antibody

Protein level used designations for IL12RB1

interleukin-12 receptor subunit beta-1 , interleukin 12 receptor, beta 1 , IL12 receptor beta 1 subunit , interleukin-12 receptor subunit beta-1-like , IL-12 receptor beta component , IL-12 receptor subunit beta-1 , IL-12R subunit beta-1 , interleukin-12 receptor beta-1 chain , IL-12R-beta-1 , Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component)

GENE ID SPECIES
171333 Rattus norvegicus
484828 Canis lupus familiaris
524299 Bos taurus
574199 Macaca mulatta
100271900 Sus scrofa
100435478 Pongo abelii
100474774 Ailuropoda melanoleuca
3594 Homo sapiens
16161 Mus musculus
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