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Browse our anti-IL15 (IL15) Antibodies

Full name:
anti-Interleukin 15 Antibodies (IL15)
On are 266 Interleukin 15 (IL15) Antibodies from 32 different suppliers available. Additionally we are shipping IL15 Proteins (144) and IL15 Kits (109) and many more products for this protein. A total of 531 IL15 products are currently listed.
AI503618, IL-15, IL15

Most Popular Reactivities for anti-IL15 (IL15) Antibodies

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anti-Mouse (Murine) IL15 Antibodies:

anti-Human IL15 Antibodies:

anti-Rat (Rattus) IL15 Antibodies:

All available anti-IL15 Antibodies

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Top referenced anti-IL15 Antibodies

  1. Human Monoclonal IL15 Primary Antibody for FACS - ABIN2660775 : Armitage, Macduff, Eisenman, Paxton, Grabstein: IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 9 references for ABIN2660775

  2. Human Monoclonal IL15 Primary Antibody for FACS, Neut - ABIN4900389 : Marra, Mathew, Grigoriadis, Wu, Kyle-Cezar, Watkins, Rashid, De Rinaldis, Hessey, Gazinska, Hayday, Tutt: IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers. in Cancer research 2014 (PubMed)
    Show all 6 references for ABIN4900389

  3. Human Monoclonal IL15 Primary Antibody for FACS - ABIN4897621 : Anguille, Van Acker, Van den Bergh, Willemen, Goossens, Van Tendeloo, Smits, Berneman, Lion: Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner. in PLoS ONE 2015 (PubMed)
    Show all 5 references for ABIN4897621

  4. Human Monoclonal IL15 Primary Antibody for Func - ABIN1107803 : Bernard, Harb, Mortier, Quéméner, Meloen, Vermot-Desroches, Wijdeness, van Dijken, Grötzinger, Slootstra, Plet, Jacques: Identification of an interleukin-15alpha receptor-binding site on human interleukin-15. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 references for ABIN1107803

  5. Mouse (Murine) Monoclonal IL15 Primary Antibody for Func - ABIN1449229 : Shih, Kurman: Molecular basis of gestational trophoblastic diseases. in Current molecular medicine 2002 (PubMed)
    Show all 4 references for ABIN1449229

  6. Human Monoclonal IL15 Primary Antibody for FACS - ABIN4897620 : Ferlazzo, Pack, Thomas, Paludan, Schmid, Strowig, Bougras, Muller, Moretta, Münz: Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 4 references for ABIN4897620

  7. Human Polyclonal IL15 Primary Antibody for ELISA, WB - ABIN4324547 : Schneider, Mohebiany, Ifergan, Beauseigle, Duquette, Prat, Arbour: B cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)

More Antibodies against IL15 Interaction Partners

Chimpanzee Interleukin 15 (IL15) interaction partners

  1. T cells in chimpanzees infected with human immunodeficiency virus express surface interleukin-15.

  2. CD3 (show CD3 Antibodies)(-) CD8 (show CD8A Antibodies)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma (show IFNG Antibodies), and that IL-15 elicits IFN-gamma (show IFNG Antibodies) production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15, CD8 (show CD8A Antibodies) antigen, IFN-gamma (show IFNG Antibodies)]

Mouse (Murine) Interleukin 15 (IL15) interaction partners

  1. Under steady-state conditions, KLF2 (show KLF2 Antibodies)-deficient NK cells alter their expression of homeostatic homing receptors and subsequently undergo apoptosis due to IL-15 starvation.

  2. The induction of IgM (show CD40LG Antibodies) and IgA, which can play pivotal roles in mucosal immunity, was promoted in the presence of IL-15. Collectively, the data implicate IL-15 as the master cytokine that induces B-1a cells to mount a mucosal immune response.

  3. The novel mechanism of IL-15 transfer to the surface of antigen-processing DCs may explain the enhanced potency of IL-15:IL-15Ralpha-coated nanoparticles for antigen delivery.

  4. Muscle FNDC5 (show FNDC5 Antibodies) mRNA expression and irisin (show FNDC5 Antibodies) release are not IL-15-dependent in mice.

  5. Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner.

  6. Impaired delivery of IL-15 to CD4 (show CD4 Antibodies)+ T cells in the colon downmodulates Foxp3 (show FOXP3 Antibodies) expression and enhances RORgammat expression. CD4 (show CD4 Antibodies)+ T cells deprived of IL-15 trigger IBD characterized by production of pro-inflammatory cytokines and accumulation of Th1 (show HAND1 Antibodies)/Th17 cells.

  7. Most (86%) IL15 in serum resides in the free state, with a minor proportion (14%) residing in complex with IL15Ralpha. Results suggest that IL15 is released as a free molecule by an unknown mechanism rather than via cleavage of membrane-bound IL15/IL15Ralpha.

  8. IL-15 may influence mononuclear phagocytes subsets in the gut (show GUSB Antibodies) in a novel way that alters the frequency of lamina propria Th17 cells.

  9. Downregulation of STAT3 (show STAT3 Antibodies) phosphorylation enhances tumoricidal effect of IL-15-activated dendritic cell against doxorubicin-resistant lymphoma and leukemia via TNF-alpha (show TNF Antibodies).

  10. Exercise-stimulated interleukin-15 is controlled by AMPK (show PRKAA1 Antibodies) and regulates skin metabolism and aging.

Human Interleukin 15 (IL15) interaction partners

  1. IL-15 is able to significantly regulate the inflammatory infiltration of macrophages in polymyositis patients through affecting the NF-kB pathway and MMP-9 (show MMP9 Antibodies) expression levels.

  2. IL-15 mRNA expression was significantly higher in patients with moderately severe viral bronchiolitis compared to controls and patients with severe disease. Serum IL15 correlated with disease severity.

  3. These data underline the potential of "free" IL15 in the absence of Ralpha-complex as a powerful and specific immuno-modulator, which may be beneficial where selective immune-activation is desired.

  4. Data indicate that high interleukin-16 (show IL16 Antibodies) (IL-6 (show IL6 Antibodies)), interferon-gamma (IFN-gamma (show IFNG Antibodies)) and low interleukin-15 (IL-15) levels suggest active tuberculosis.

  5. Culturing NK cells under hypoxia compared with ambient air (normoxia) and IL-15 priming synergistically augmented glycolytic gene expression without major changes in glycolytic flux and glucose consumption.

  6. Findings suggest for co-targeting shedding-derived soluble MIC (sMIC) to enhance the therapeutic efficacy of ALT-803 or other interleukin 15 (IL-15) agonists.

  7. Report improved antitumoral NK-cell activity in DC-based vaccine strategies through the use of IL-15/IL-15Ralpha mRNA-engineered designer DC.

  8. The novel mechanism of IL-15 transfer to the surface of antigen-processing DCs may explain the enhanced potency of IL-15:IL-15Ralpha-coated nanoparticles for antigen delivery.

  9. Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner.

  10. results demonstrated the relative functional deficiencies of alpha-GalCer induced UCB iNKT cells, which can be ameliorated by IL-15

Pig (Porcine) Interleukin 15 (IL15) interaction partners

  1. Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.

  2. results demonstrate that porcine reproductive and respiratory syndrome virus (PRRSV)infection could induce IL-15 production in macrophages/dendritic cells; data further show that upregulation of IL-15 by PRRSV requires PKC (show FYN Antibodies) and NF-kappaB (show NFKB1 Antibodies) pathways

  3. IFN-gamma (show IFNG Antibodies) targets the adipocyte to induce IL-15 expression, thus indicating a possible role for the adipocyte in the regulation of T-cell function and muscle metabolism during the innate immune response

  4. When induced by IFN-gamma (show IFNG Antibodies) or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response.

Cow (Bovine) Interleukin 15 (IL15) interaction partners

  1. Increased function and survival of IL-15-transduced dendritic cells are mediated by up-regulation of IL-15Ralpha and Bcl-2 (show BCL2 Antibodies).

Rhesus Monkey Interleukin 15 (IL15) interaction partners

  1. IL 15 generates a dramatic expansion of short-lived memory CD8 (show CD8A Antibodies) T cells and natural killer in immunocompetent macaques and has long-term effects on the balance of CD4 (show CD4 Antibodies)(+) and CD8 (show CD8A Antibodies)(+) T cells.

  2. These data suggest that therapeutic use of IL-15 in the setting of antiretroviral therapy might facilitate specific restoration of the CD4 (show CD4 Antibodies) + T cell compartment.

  3. IL-15 secretion significantly correlates with the up-regulated expression of CD4 (show CD4 Antibodies) on memory CD4 (show CD4 Antibodies) T cells that is associated with increased permissiveness to simian immunodeficiency virus infection.

IL15 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.

Alternative names and synonyms associated with IL15

  • interleukin 15 (IL15) antibody
  • interleukin 15 (Il15) antibody
  • AI503618 antibody
  • IL-15 antibody
  • IL15 antibody

Protein level used designations for anti-Interleukin 15 (IL15) Antibodies

interleukin 15 , interleukin-15 , IL-15

737808 Pan troglodytes
100034058 Equus caballus
16168 Mus musculus
3600 Homo sapiens
25670 Rattus norvegicus
403584 Canis lupus familiaris
397683 Sus scrofa
281248 Bos taurus
100009017 Oryctolagus cuniculus
395258 Gallus gallus
100379533 Cavia porcellus
493682 Felis catus
443056 Ovis aries
699616 Macaca mulatta
100484790 Ailuropoda melanoleuca
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