Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL-15 Products

(Interleukin 15 (IL15))

Categories

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured IL-15 Categories

IL-15 Antibodies

High quality antibodies with extensive validation data.

IL-15 ELISA Kits

Reliable ELISA kits for a wide range of species.

IL-15 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL-15 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7430678
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN517140
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7430681
Quantity 100 μL
Datasheet Datasheet

Recommended IL-15 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957032
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957033
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957034
Quantity 96 tests
Datasheet Datasheet

Recommended IL-15 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (5)
Cat. No. ABIN7274953
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN6239761
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123549
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IL-15 products

Zhuang, Yi, Chen, Kang, Chen, Chen, Cui, Chang, Ye, Ni, Wang, Du, Li, Liu, Jian, Li, Gao, Li, Li: "Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion." in: Cell death & disease, Vol. 11, Issue 6, pp. 453, (2020) (PubMed).

Wu, Wu, Ye, Yu, He, Chen: "Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 255, pp. 81-93, (2018) (PubMed).

Molanouri Shamsi, Chekachak, Soudi, Quinn, Ranjbar, Chenari, Yazdi, Mahdavi: "Combined effect of aerobic interval training and selenium nanoparticles on expression of IL-15 and IL-10/TNF-α ratio in skeletal muscle of 4T1 breast cancer mice with cachexia." in: Cytokine, Vol. 90, pp. 100-108, (2018) (PubMed).

Akieda-Asai, Ida, Miyazato, Kangawa, Date: "Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes." in: Peptides, Vol. 99, pp. 14-19, (2018) (PubMed).

Rekik, Smiti Khanfir, Larbi, Zamali, Beldi-Ferchiou, Kammoun, Marzouki, Hamzaoui, Mrad, Barbouche, Houman, Ben Ahmed: "Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22." in: Cytokine, Vol. 108, pp. 182-189, (2018) (PubMed).

Pangrazzi, Meryk, Naismith, Koziel, Lair, Krismer, Trieb, Grubeck-Loebenstein: ""Inflamm-aging" influences immune cell survival factors in human bone marrow." in: European journal of immunology, Vol. 47, Issue 3, pp. 481-492, (2017) (PubMed).

Gorvel, Korenfeld, Tung, Klechevsky: "Dendritic Cell-Derived IL-32α: A Novel Inhibitory Cytokine of NK Cell Function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1290-1300, (2017) (PubMed).

Ciccocioppo, Gallia, Avanzini, Betti, Picone, Vanoli, Paganini, Biagi, Maccario, Corazza: "A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions." in: Mayo Clinic proceedings, Vol. 91, Issue 6, pp. 812-9, (2016) (PubMed).

Shi, Liu, Zhang, Guo, Song, Song, Liu: "miR-15b is Downregulated in Myasthenia Gravis Patients and Directly Regulates the Expression of Interleukin-15 (IL-15) in Experimental Myasthenia Gravis Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1774-80, (2015) (PubMed).

Collignon, Perles-Barbacaru, Robert, Silvy, Martinez, Crenon, Germain, Garcia, Viola, Lombardo, Mas, Béraud: "A pancreatic tumor-specific biomarker characterized in humans and mice as an immunogenic onco-glycoprotein is efficient in dendritic cell vaccination." in: Oncotarget, Vol. 6, Issue 27, pp. 23462-79, (2015) (PubMed).

Synonyms and alternative names related to IL-15

interleukin 15 (IL15), interleukin 15 (Il15), AI503618, IL-15, IL15

Protein level used designations for IL-15

  • interleukin 15
  • interleukin-15
  • IL-15
You are here:
Support