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anti-Human IL15RA Antibodies:
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Human Monoclonal IL15RA Primary Antibody for FACS - ABIN2663180
Lorenzen, Dingley, Jacques, Grötzinger: The structure of the interleukin-15 alpha receptor and its implications for ligand binding. in The Journal of biological chemistry 2006
Show all 10 references for ABIN2663180
Human Monoclonal IL15RA Primary Antibody for GS, ELISA - ABIN2657042
Sato, Patel, Waldmann, Tagaya: The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells. in Proceedings of the National Academy of Sciences of the United States of America 2007
Show all 9 references for ABIN2657042
Human Monoclonal IL15RA Primary Antibody for CMCD, Dep - ABIN2660994
Giri, Kumaki, Ahdieh, Friend, Loomis, Shanebeck, DuBose, Cosman, Park, Anderson: Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. in The EMBO journal 1995
Show all 9 references for ABIN2660994
significant association of rs2228059 with ossification of the posterior longitudinal ligament of the spine in Chinese Han population
NK cell activation in human hantavirus infection explained by virus-induced IL-15 (show IL15 Antibodies)/IL15Ralpha expression
IRF-1 (show IRF1 Antibodies) promotes LTx I/R injury via hepatocyte IL-15 (show IL15 Antibodies)/IL-15Ralpha production and suggest that targeting IRF-1 (show IRF1 Antibodies) and IL-15 (show IL15 Antibodies)/IL-15Ralpha may be effective in reducing I/R injury associated with LTx.
Coexpression of IL15RA and IL15 (show IL15 Antibodies) was also sufficient to activate peripheral blood mononuclear cells.
Circulating levels of IL-15 (show IL15 Antibodies) and IL-15Ralpha seem to reflect visceral distribution of adipose tissue; epicardial fat may be a potential source of both IL-15 (show IL15 Antibodies) and IL-15Ralpha.
our study provides strong evidence that the functional IL-15RA rs2228059 A>C polymorphism may contribute to the risk of ESCC.
We show that a gene transfer approach using recombinant adenovirus to express IL-15 (show IL15 Antibodies) and IL-15Ralpha in murine TRAMP (show DPT Antibodies)-C2 prostate or TS/A breast tumors induced antitumor immune responses
This present study demonstrated that IL15RA rs2228059 A > C polymorphism might modify Gastric cardiac adenocarcinoma susceptibility
Data suggest that the Interleukin (IL)-15 (show IL15 Antibodies) and interleukin 15 receptor alpha (IL-15 (show IL15 Antibodies).IL-15Ralpha) complex cleaved from presenting cells allows responding cells to internalize, store and use IL-15 (show IL15 Antibodies).IL-15Ralpha complex for their own proliferation and survival.
Data indicate that tumor necrosis factor-alpha (TNF (show TNF Antibodies)) abolishes nuclear localization of IL-15 (show IL15 Antibodies) and IL-15Ralpha by acting on chromosomal region maintenance 1 (CRM1 (show XPO1 Antibodies)), and it facilitates exocytosis of IL-15 (show IL15 Antibodies) with the involvement of ADP-ribosylation factor 6 (ARF6 (show ARF6 Antibodies)).
Spontaneous cage activity was not different and IL-15 (show IL15 Antibodies) protein levels were lower in male and female mIl15ra(fl/fl (show FLT3LG Antibodies))/Cre(+) mice.
Despite being protected against diet induced obesity, IL-15R alpha knockout mice are hyperglycemic and insulin (show INS Antibodies)-resistant.
IL-15 (show IL15 Antibodies) directly induces pro-oxidative gene expression in primary myogenic cultures. Primary myogenic cultures require IL-15RA to respond to IL-15 (show IL15 Antibodies).
we found that aging-related functional NK cell deficiency was completely reversed by injecting soluble IL-15 (show IL15 Antibodies)/IL-15Ralpha complexes.
a greater mitochondrial density and mitochondrial DNA content was found in fast muscles from IL-15-Receptor-alpha KO mice that was not due to the presence of smaller muscle fibers.
IL-15 (show IL15 Antibodies) is produced and secreted only as a heterodimer with IL-15Ralpha.
IL-15 (show IL15 Antibodies) can signal via IL-15Ralpha, JNK (show MAPK8 Antibodies), and NF-kappaB (show NFKB1 Antibodies) to drive RANTES (show CCL5 Antibodies) production by myeloid cells.
Stage 3 thymic invariant natural killer NKT (show CTSL1 Antibodies) cells are specifically reduced in IL-15Ralpha-deficient mice, whereas the acquisition of natural killer (NK) receptors occurs at stage 3 IL15 (show IL15 Antibodies)-dependent thymic cell development.
Different levels of IL-15 (show IL15 Antibodies) trans-presentation are required for different natural killer (NK) cell developmental events to reach full maturation status
IL-15 receptor alpha has a role in endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
interleukin-15 receptor subunit alpha
, interleukin 15 receptor alpha
, interleukin 15 receptor, alpha
, interleukin 15 receptor, alpha chain
, IL-15 receptor subunit alpha