IL15RA antibody (AA 31-205)

Catalog No. ABIN7193409

Product Details anti-IL15RA Antibody

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Binding Specificity: AA 31-205

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Neutralization (Neut), Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human CD215 (AA: extra 31-205) expressed in E. coli.

Clone: 5F10D9

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, ICC:N/A, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: CD215 (IL15RA Products)

Synonyms: IL15RA antibody, CD215 antibody, AA690181 antibody, IL-15RA antibody, interleukin 15 receptor subunit alpha antibody, interleukin 15 receptor, alpha chain antibody, IL15RA antibody, Il15ra antibody

Background:

Description: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]

Aliases: IL15RA

Molecular Weight: 28.2 kDa

Gene ID: 3601

Pathways: JAK-STAT Signaling