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Mouse (Murine) IL2 ELISA Kit for Sandwich ELISA - ABIN411296
Liu, Shen, Wei, Mao, Huang: Immunomodulatory activity of butanol extract from Solanum lyratum in tumor-bearing mice. in Immunopharmacology and immunotoxicology 2011
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Human IL2 ELISA Kit for Sandwich ELISA - ABIN411295
Chen, Ni, Ye, Sun, Li, Xu: Stephanthraniline A inhibits the proliferation and activation of T cells in vitro and in vivo. in European journal of pharmacology 2012
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Rat (Rattus) IL2 ELISA Kit for Sandwich ELISA - ABIN921062
Lowenthal, Zubler, Nabholz, MacDonald: Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. in Nature 1985
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Mouse (Murine) IL2 ELISA Kit for Sandwich ELISA - ABIN625143
Sun, Wei, Sun, Xiao, Yang, Tian: Human interleukin-15 improves engraftment of human T cells in NOD-SCID mice. in Clinical and vaccine immunology : CVI 2006
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Chicken IL2 ELISA Kit for Sandwich ELISA - ABIN364734
Moeini, Omar, Rahim, Yusoff: Improving the potency of DNA vaccine against chicken anemia virus (CAV) by fusing VP1 protein of CAV to Marek's Disease Virus (MDV) type-1 VP22 protein. in Virology journal 2011
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Rat (Rattus) IL2 ELISA Kit for Sandwich ELISA - ABIN416247
Zhang, Wu, Luo, Li, Cheng, Miron: Synthesis and inflammatory response of a novel silk fibroin scaffold containing BMP7 adenovirus for bone regeneration. in Bone 2012
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Mouse (Murine) IL2 ELISA Kit for Sandwich ELISA - ABIN1305301
Cherukuri, Cheng, Sohn, Pierce: The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts. in Immunity 2001
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Human IL2 ELISA Kit for Sandwich ELISA - ABIN2690564
Stern, Pan, Urdal, Mochizuki, DeChiara, Blacher, Wideman, Gillis: Purification to homogeneity and partial characterization of interleukin 2 from a human T-cell leukemia. in Proceedings of the National Academy of Sciences of the United States of America 1984
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Human IL2 ELISA Kit for Sandwich ELISA - ABIN625022
Meltzer, Standley: Modeled repetitive motion strain and indirect osteopathic manipulative techniques in regulation of human fibroblast proliferation and interleukin secretion. in The Journal of the American Osteopathic Association 2008
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Mouse (Murine) IL2 ELISA Kit for Sandwich ELISA - ABIN415510
Rocha, Calvo, Chaves, Peron, Marques, de Borba, Braga, Pereira, Vicente, Chammas, Schor, Bellini: Endostatin- and interleukin-2-expressing retroviral bicistronic vector for gene therapy of metastatic renal cell carcinoma. in The journal of gene medicine 2011
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IL-2 had moderate protein homology (30.9% identity/48.3% similarity) with Fugu IL-2, the only IL-2 homologue identified in fish to date, with lower homology to avian (17.8% identity/23.2% similarity) and mammalian (34.2 identity/46.5% similarity) IL-2s
Pretreatment of neonatal PBMC with IL-1beta (show IL1B ELISA Kits), TNF-alpha (show TNF ELISA Kits) or IFN-gamma (show IFNG ELISA Kits) promotes mitogenic response to ConA through up-regulating the production of IL-2 and the expression of the mature IL-2 receptor.
Data reported that let-7i upregulates IL-2 expression by targeting the promoter TATA-box region, which functions as a positive regulator. In HIV-1 infection, the expression of let-7i in CD4 (show CD4 ELISA Kits)(+) T cells is decreased by attenuating its promoter activity. The reduced let-7i miRNA expression led to a decline in IL-2 levels which contributes to CD4 (show CD4 ELISA Kits)(+) T cells death.
IL-2 and IL-6 (show IL6 ELISA Kits) work together to enhance influenza-specific CD8 (show CD8A ELISA Kits) T cell generation responding to live influenza virus in aged mice and humans
Results showed that plasma and mRNA levels of IL-2, IFN-gamma (show IFNG ELISA Kits), IL-4 (show IL4 ELISA Kits), and IL-17A (show IL17A ELISA Kits) in primary immune thrombocytopenia patients did not change significantly after TPO (show THPO ELISA Kits)-RA treatment, whereas TGF-beta1 (show TGFB1 ELISA Kits) levels increased remarkably.
the aim of the current review article is to determine the roles of IL-2 IL-2/IL-2R interaction in polyoma BK virus reactivation and PBK (show PBK ELISA Kits) associated nephropathy complications.
Modulation of IL-2, IL-4 (show IL4 ELISA Kits), IFN-gamma (show IFNG ELISA Kits) and/or TNF-alpha (show TNF ELISA Kits) levels, or inhibitors of Erk1/2 (show MAPK1/3 ELISA Kits) or S6K1 (show RPS6KB1 ELISA Kits) may be a new approach to prevent BAFF (show TNFSF13B ELISA Kits)-induced aggressive B-cell malignancies.
Our results show that the frequency of Tregs is altered in a large cohort of long-term T1D patients, a profound decrease in CD25 (show IL2RA ELISA Kits) expression and altered IL-2 signaling are typical features of Tregs populations in long-term diabetic patients and their relatives.
a role for circulating IL-2 in liver dysfunction and propose that a combined assessment of AST/ALT in conjunction with IL-2 at the early stages of symptomatic DENV infection may be useful to predict the severe forms of dengue.
Lymphocytes incubated in the presence of IL-2 lose the capacity for chemotaxis but acquire antitumor activity
the central biological role of the novel IL-2-R/Lck (show LCK ELISA Kits)/PLCgamma/PKCtheta (show PRKCQ ELISA Kits);/alphaPIX (show ARHGEF6 ELISA Kits)/Rac1/PYGM (show PYGM ELISA Kits) signalling pathway is directly related to the control of fundamental cellular processes such as T cell migration and proliferation.
F42K can circumvent the expansion and negative immunoregulatory effects of highly suppressive ICOS (show CTLA4 ELISA Kits)+ Tregs, while promoting NK cell expansion and function. F42K also induces a unique gene expression profile and does not activate many IL2-induced genes, although it has the capacity to activate NK cells and NK cell-associated activation genes, costimulatory molecules, and NK-mediated cytolytic function
Genetic ablation of the IL2Rbeta chain on CD8 (show CD8A ELISA Kits)(+) T cells restrains inhibitory receptor induction, in particular 2B4 (show CD244 ELISA Kits) and Tim-3 (show HAVCR2 ELISA Kits); precludes terminal differentiation of highly defective PD-1 (show PDCD1 ELISA Kits)(hi) effectors; and rescues memory T-cell development and responsiveness to IL-7 (show IL7 ELISA Kits)-dependent signals. Together, we ascribe a previously unexpected role to IL-2 and IL-15 (show IL15 ELISA Kits) as instigators of CD8 (show CD8A ELISA Kits)(+) T-cell exhaustion during chronic viral infe...
this report, we elucidated the unsolved mechanism of the anti-cancer effect of curcumin by identifying IL-2 as a direct molecular target. Curcumin, as a small molecule IL-2 modulator, has the potential to be used to treat IL-2 related pathologic conditions.
Data show that PTEN plays a key role in Th17 cell differentiation by blocking IL-2 expression.
AnxA6 (show ANXA6 ELISA Kits) regulates IL-2 homeostasis and sensitivity in T cells by sustaining a lipid raft-like membrane environment.
NOD Treg cells have an impaired responsiveness to IL-2 that reduces their ability to compete for a limited supply of IL-2.
Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice.
At single cell level, IL-2 is binary (digital) and CD25 (show IL2RA ELISA Kits) is graded expressed, whereas at population level both parameters show graded expression correlating with the antigen amount.
IL-2/anti-IL-2 complexes protected lupus-prone mice against lupus nephritis by expanding Tregs.
Data indicate that IL-2 can augment the gammadeltaT-17 response in favor of short-lived effectors with limited plasticity, particularly in the presence of IL-1beta (show IL1B ELISA Kits) and IL-23 (show IL23A ELISA Kits). In this way, IL-2 may act to curtail the innate-like response of gammadeltaT-17 cells upon arrival of IL-2-producing adaptive immune cells at the site of inflammation.
We observed that besides TCR stimulation Tregs require IL-2 for activation.
The isolation and characterization of interleukin 2 from Tibetan swine are reported.
IL-2 activates the STAT3 (show STAT3 ELISA Kits) pathway, protects the lens epithelium cells and reduce the damage caused by inflammation reactions.
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
, T-cell growth factor
, T cell growth factor
, involved in regulation of T-cell clonal expansion
, interleukin-2 precursor protein