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IKZF1 ELISA Kits

(IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2011].
IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) ELISA Kit IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) ELISA Kit IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) ELISA Kit (ABIN6967566)

IKZF1 Reactivity: Human Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

IKZF1 ELISA Kits by Reactivity

Find IKZF1 ELISA Kits for a variety of species such as anti-Chicken IKZF1, anti-Human IKZF1, anti-Mouse IKZF1. The species listed below are among those available. Click on a link to go to the corresponding products.

IKZF1 ELISA Kits by Detection Method

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IKZF1 ELISA Kits by Analytical Method

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Popular IKZF1 ELISA Kits

Aliases for IKZF1 ELISA Kits

IKAROS family zinc finger 1 (IKZF1) ELISA Kits
IKAROS family zinc finger 1 (Ikzf1) ELISA Kits
IKAROS family zinc finger 1 (Ikaros) (ikzf1) ELISA Kits
IKAROS family zinc finger 1 (ikzf1) ELISA Kits
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