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Browse our anti-IL21 (IL21) Antibodies

Full name:
anti-Interleukin 21 Antibodies (IL21)
On are 210 Interleukin 21 (IL21) Antibodies from 31 different suppliers available. Additionally we are shipping IL21 Kits (82) and IL21 Proteins (71) and many more products for this protein. A total of 376 IL21 products are currently listed.
IL-21, Za11

Most Popular Reactivities for anti-IL21 (IL21) Antibodies

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anti-Human IL21 Antibodies:

anti-Mouse (Murine) IL21 Antibodies:

anti-Rat (Rattus) IL21 Antibodies:

All available anti-IL21 Antibodies

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Top referenced anti-IL21 Antibodies

  1. Mouse (Murine) Monoclonal IL21 Primary Antibody for ICFC - ABIN2657956 : Bauquet, Jin, Paterson, Mitsdoerffer, Ho, Sharpe, Kuchroo: The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. in Nature immunology 2009 (PubMed)
    Show all 8 references for ABIN2657956

  2. Human Monoclonal IL21 Primary Antibody for ICFC - ABIN2666224 : Asao, Okuyama, Kumaki, Ishii, Tsuchiya, Foster, Sugamura: Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 4 references for ABIN2666224

  3. Human Monoclonal IL21 Primary Antibody for FACS - ABIN2663778 : Dumoutier, Van Roost, Colau, Renauld: Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 4 references for ABIN2663778

  4. Human Monoclonal IL21 Primary Antibody for FACS - ABIN2657954 : Parrish-Novak, Dillon, Nelson, Hammond, Sprecher, Gross, Johnston, Madden, Xu, West, Schrader, Burkhead, Heipel, Brandt, Kuijper, Kramer, Conklin, Presnell, Berry, Shiota, Bort, Hambly, Mudri, Clegg et al.: Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. ... in Nature 2000 (PubMed)
    Show all 4 references for ABIN2657954

  5. Human Polyclonal IL21 Primary Antibody for WB - ABIN657761 : Petukhova, Duvic, Hordinsky, Norris, Price, Shimomura, Kim, Singh, Lee, Chen, Meyer, Paus, Jahoda, Amos, Gregersen, Christiano: Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. in Nature 2010 (PubMed)
    Show all 3 references for ABIN657761

  6. Human Polyclonal IL21 Primary Antibody for ELISA, WB - ABIN1452162 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)
    Show all 2 references for ABIN1452162

  7. Cow (Bovine) Polyclonal IL21 Primary Antibody for EIA, WB - ABIN401062 : Muneta, Kikuma, Yoshihara, Mori: Cloning, expression, and tissue distribution of bovine interleukin-21. in Veterinary immunology and immunopathology 2003 (PubMed)

  8. Human Polyclonal IL21 Primary Antibody for IF (p), IHC (p) - ABIN748133 : Guan, Wang, Meng, Shi, Jiang, Xiao, Shi, Xu, Zhang: Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease. in Cytokine 2015 (PubMed)

More Antibodies against IL21 Interaction Partners

Human Interleukin 21 (IL21) interaction partners

  1. IL-21 (show IL17C Antibodies) exerts major effects on B-cell activation (show BLNK Antibodies) and differentiation or apoptosis during humoral immune responses, and also affects different subtypes of T cells. (Review)

  2. The results suggest that IL-21 (show IL17C Antibodies) promotes migration and invasion of Rheumatoid arthritis-Fibroblast-like synoviocytes. Therefore, therapeutic strategies targeting IL-21 (show IL17C Antibodies) might be effective for the treatment of Rheumatoid arthritis.

  3. IL-12 (show IL12A Antibodies) induced the generation of IL-21 (show IL17C Antibodies)- and IFN-gamma (show IFNG Antibodies)-co-expressing poly-functional CD4 (show CD4 Antibodies)+ T cells from human naive CD4 (show CD4 Antibodies)+ T cells.

  4. IL-21 (show IL17C Antibodies) expression is promoted by MEKK4 (show MAP3K4 Antibodies) in malignant T cells and is associated with progression risk in cutaneous T-cell lymphoma

  5. Human IL-21 (show IL17C Antibodies)+IFN-gamma (show IFNG Antibodies)+CD4 (show CD4 Antibodies)+ T cells in nasal polyps are regulated by IL-12 (show IL12A Antibodies).

  6. CD3(+)TCRvbeta11(+) NKT cells from a local site of M. tuberculosis infection produce IL-21, express CXCR5 and CD40L, help B cells to secrete IgG and IgA, and may participate in local immune responses against M. tuberculosis infection.

  7. IL-21 (show IL17C Antibodies) protein was higher in serum and mRNA and protein were higher in disc tissue of patients with lumbar disc herniation compared to controls.

  8. both IL-21 (show IL17C Antibodies) rs907715 and rs2221903 polymorphisms may be associated with systemic lupus erythematosus susceptibility (meta-analysis)

  9. all Ifng (show IFNG Antibodies)+ T cells produced IL-21 (show IL17C Antibodies), but only a small percentage of highly proliferative Ifng (show IFNG Antibodies)+ T cells maintained a T-bethi phenotype

  10. The high levels of memory and activated B cells and follicular helper T cells were positively associated with the progression of immunoglobulin A nephropathy. This may be mediated by the overexpression of AID, which is potentially regulated by IL21 (show IL17C Antibodies).

Mouse (Murine) Interleukin 21 (IL21) interaction partners

  1. this study reveals a context-dependent role for IL-21 in sustaining effector phenotype CD8 (show CD8A Antibodies) T cells and influencing their migratory properties, accumulation, and functions.

  2. Dysregulated development of IL-17 (show IL17A Antibodies)- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORgammat.

  3. results demonstrate that, in the setting of lupus-like CD4 (show CD4 Antibodies) T cell-driven B cell hyperactivity, IL-21 signaling on Ag-specific donor CD8 (show CD8A Antibodies) T cells is critical for CTL effector maturation whereas a lack of IL-21R (show IL21R Antibodies) downregulates CTL responses that would otherwise limit B cell hyperactivity and autoantibody production

  4. Gene expression analyses of angioimmunoblastic T-cell lymphoma (AITL), showed that essentially all cases expressed elevated levels of transcripts for IL21, IL21R (show IL21R Antibodies), and a series of genes associated with TFH cell development and function.

  5. IL-21 from microbiota-specific Th17 and/or Tfh cells contributes to robust intestinal IgA levels by enhancing IgA(+) CSR, IgA production and B-cell trafficking into the intestine.

  6. this report demonstrates a critical role for IL-21 in the generation of a primary effector CD8 (show CD8A Antibodies) T cell response to an infectious disease model.

  7. IL-21 drives the activation and expansion of a novel population of IL-13 (show IL13 Antibodies)-producing Tc2 (show TCN2 Antibodies) cells, which serve as a critical link between inflammation and fibrosis.

  8. these findings underscore the important collaboration between IL-4 (show IL4 Antibodies) and IL-21 in shaping T-dependent B cells antibody responses.

  9. IL-21-mediated signaling supports generation and stabilization of pathogenic Th17 cells and development of spontaneous autoimmunity.

  10. In vivo treatment with IL-21 results in complete mantle cell lymphoma regression in syngeneic mice via natural killer - and T-cell-dependent mechanisms.

Cow (Bovine) Interleukin 21 (IL21) interaction partners

  1. The results revealed that the peak expression of IL6 (show IL6 Antibodies) and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.

IL21 Antigen Profile

Antigen Summary

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with IL21

  • interleukin 21 (IL21) antibody
  • interleukin 21 (Il21) antibody
  • interleukin 21-like (LOC100344172) antibody
  • IL-21 antibody
  • Za11 antibody

Protein level used designations for anti-Interleukin 21 (IL21) Antibodies

interleukin-21 , interleukin-21 isoform , IL-21

59067 Homo sapiens
60505 Mus musculus
365769 Rattus norvegicus
378475 Bos taurus
100726049 Cavia porcellus
442935 Canis lupus familiaris
403123 Sus scrofa
100861248 Capra hircus
554218 Gallus gallus
100862657 Ovis aries
100344172 Oryctolagus cuniculus
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