Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Mouse (Murine) IL21 Primary Antibody for ELISA - ABIN1672800
Nurieva, Yang, Martinez, Zhang, Panopoulos, Ma, Schluns, Tian, Watowich, Jetten, Dong: Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. in Nature 2007
Show all 4 references for ABIN1672800
Human IL21 Primary Antibody for ELISA - ABIN365231
Aldinucci, Celegato, Borghese, Colombatti, Carbone: IRF4 silencing inhibits Hodgkin lymphoma cell proliferation, survival and CCL5 secretion. in British journal of haematology 2010
IL-21 (show IL17C ELISA Kits) is involved in the pathological development of Intervertebral Disc Degeneration and IL-21 (show IL17C ELISA Kits) could aggravate IVD (show IVD ELISA Kits) degeneration by stimulating TNF-alpha (show TNF ELISA Kits) through the STAT (show STAT1 ELISA Kits) signaling pathway
Our findings suggest that the rs12508721T/C and rs2221903A/G polymorphisms of IL-21 (show IL17C ELISA Kits) gene are associated with the susceptibility of HBV-related hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) and chronic HBV infection. The genetic variant may in fact cause protection against the HBV-related HCC (show FAM126A ELISA Kits).
Hepatitis C virus specific IL-21 (show IL17C ELISA Kits) producing T cells but not IL-17A (show IL17A ELISA Kits) producing T Cells are associated with hepatitis C viral control in HIV/ hepatitis C virus coinfection.
this study shows that the serum levels of IL-21 (show IL17C ELISA Kits) are higher in Iranian diabetes type I patients compared to the healthy individuals
We characterized the expressed IL-21 (show IL17C ELISA Kits) gene from immune tissues of two macropod species, the tammar wallaby (Macropus eugenii), a model macropod, and the closely related endangered bridled nailtail wallaby (Onychogalea fraenata). The open reading frame of macropod IL-21 (show IL17C ELISA Kits) is 462 nucleotides in length and encodes a 153-mer (show MERTK ELISA Kits) putative protein that has 46% identity with human IL-21 (show IL17C ELISA Kits).
The rs2055979 C>A polymorphism of the IL-21 gene is associated with cryptorchidism susceptibility, and the C allele increases the risk of cryptorchidism in a Chinese Han population.
Polymorphisms in IL21 (show IL17C ELISA Kits) may be associated with sepsis risk
review on IL-21 (show IL17C ELISA Kits) as is a crucial cytokine associated with pemphigus
There is a strong association between IL2 (show IL2 ELISA Kits)/IL21 (show IL17C ELISA Kits) rs6822844 variant and susceptibility to rheumatoid arthritis (RA) in the Algerian population; this association is independent from the autoantibodies status of RA patients.
HCV infection increased the frequency of CD4 (show CD4 ELISA Kits)+CXCR5 (show CXCR5 ELISA Kits)+ T cells and decreased the frequency of CD27 (show CD27 ELISA Kits)+IgG+ B cells. CD4 (show CD4 ELISA Kits)+CXCR5 (show CXCR5 ELISA Kits)+ T cells activated CD27 (show CD27 ELISA Kits)+IgG+ B cells via the secretion of IL-21 (show IL17C ELISA Kits).
The data of this study suggested that an increase in astrocyte-derived IL-21 expression in hippocampal subregions following KA-induced seizures may have potent regulatory effects on epileptogenesis.
this study reveals a context-dependent role for IL-21 in sustaining effector phenotype CD8 (show CD8A ELISA Kits) T cells and influencing their migratory properties, accumulation, and functions.
Dysregulated development of IL-17 (show IL17A ELISA Kits)- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORgammat.
results demonstrate that, in the setting of lupus-like CD4 (show CD4 ELISA Kits) T cell-driven B cell hyperactivity, IL-21 signaling on Ag-specific donor CD8 (show CD8A ELISA Kits) T cells is critical for CTL effector maturation whereas a lack of IL-21R (show IL21R ELISA Kits) downregulates CTL responses that would otherwise limit B cell hyperactivity and autoantibody production
Gene expression analyses of angioimmunoblastic T-cell lymphoma (AITL), showed that essentially all cases expressed elevated levels of transcripts for IL21, IL21R (show IL21R ELISA Kits), and a series of genes associated with TFH cell development and function.
IL-21 from microbiota-specific Th17 and/or Tfh cells contributes to robust intestinal IgA levels by enhancing IgA(+) CSR, IgA production and B-cell trafficking into the intestine.
this report demonstrates a critical role for IL-21 in the generation of a primary effector CD8 (show CD8A ELISA Kits) T cell response to an infectious disease model.
IL-21 drives the activation and expansion of a novel population of IL-13 (show IL13 ELISA Kits)-producing Tc2 (show TCN2 ELISA Kits) cells, which serve as a critical link between inflammation and fibrosis.
these findings underscore the important collaboration between IL-4 (show IL4 ELISA Kits) and IL-21 in shaping T-dependent B cells antibody responses.
IL-21-mediated signaling supports generation and stabilization of pathogenic Th17 cells and development of spontaneous autoimmunity.
The results revealed that the peak expression of IL6 (show IL6 ELISA Kits) and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, interleukin-21 isoform