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Human IL21 ELISA Kit for Sandwich ELISA - ABIN417214
Li, Rauniyar, Yin, Hu, Ouyang, Xiao, Yang: Serum IL-21 levels decrease with glucocorticoid treatment in myasthenia gravis. in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014
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Mouse (Murine) IL21 ELISA Kit for Sandwich ELISA - ABIN625144
Su, Duan, Liang, Feng-Wang, Zheng, Fu, Yan, Ling-Huang, Wang: Lycium barbarum polysaccharides as an adjuvant for recombinant vaccine through enhancement of humoral immunity by activating Tfh cells. in Veterinary immunology and immunopathology 2014
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Human IL21 ELISA Kit for Sandwich ELISA - ABIN365231
Aldinucci, Celegato, Borghese, Colombatti, Carbone: IRF4 silencing inhibits Hodgkin lymphoma cell proliferation, survival and CCL5 secretion. in British journal of haematology 2010
Mouse (Murine) IL21 ELISA Kit for Sandwich ELISA - ABIN1672800
Nurieva, Yang, Martinez, Zhang, Panopoulos, Ma, Schluns, Tian, Watowich, Jetten, Dong: Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. in Nature 2007
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Report efficient retroviral vector transduction of primary human natural killer cells that were stimulated by a combination of IL-2 (show IL2 ELISA Kits) and engineered K562 cells expressing membrane-bound IL-21 (show IL17C ELISA Kits) for cancer immunotherapy.
IL21 (show IL17C ELISA Kits) reduction in osteosarcoma patients due to PD-1 (show PDCD1 ELISA Kits) and pd-L1 (show CD274 ELISA Kits) mediated follicular helper T cells suppression.
this study shows that induction of IL-21 (show IL17C ELISA Kits) in T follicular helper cells is an indicator of influenza vaccine response in a HIV-infected pediatric cohort
IL-21 (show IL17C ELISA Kits) levels in rheumatoid arthritis synovial fluid were associated with matrix metalloproteinase (MMP)-1 (show MMP1 ELISA Kits) and MMP-3 (show MMP3 ELISA Kits).
the elevated level of IL-2 (show IL2 ELISA Kits)+ and IL-21 (show IL17C ELISA Kits)+ T cells and a positive correlation between IL-21 (show IL17C ELISA Kits)+ cells with clinical activity index in ulcerative colitis patients may contribute to the pathogenesis of disease.
these results demonstrate a novel function for IL-21 (show IL17C ELISA Kits) in tuning NK and CD4 (show CD4 ELISA Kits)+ T cell interactions promoting a specific expansion of central memory lymphocytes
Combined IL-21 (show IL17C ELISA Kits)-primed polyclonal CTL plus CTLA4 (show CTLA4 ELISA Kits) blockade controls refractory metastatic melanoma in a patient
Our work suggests that IL-21 (show IL17C ELISA Kits) regulates megakaryocyte development and platelet homeostasis. Thus, IL-21 (show IL17C ELISA Kits) may link immune responses to physiological or pathological platelet-dependent processes.
this study shows that Th17/Treg imbalance and increased IL-21 (show IL17C ELISA Kits) are associated with liver injury in patients with chronic HBV infection
The findings of the current study indicate an association between IL-21 (show IL17C ELISA Kits)+TFH cells and disease activity. IL-21 (show IL17C ELISA Kits)+TFH levels may prove to be a useful marker of disease activity in OA patients.
IL-6 (show IL6 ELISA Kits) is identified as a master regulator of IL-21 in effector CD8 (show CD8A ELISA Kits)(+) T cells.
Our work suggests that IL-21 regulates megakaryocyte development and platelet homeostasis. Thus, IL-21 may link immune responses to physiological or pathological platelet-dependent processes.
we identify novel distal regulatory elements in the mouse Il21 locus and demonstrate a dynamic long-range chromatin interaction between the Il21 promoter and these regulatory elements, which contributes to the regulated expression of IL-21
this study shows that IL-21 acts as a potent inhibitor of a IL-17A (show IL17A ELISA Kits)-producing T-cell subset during Mycobacterium bovis Bacillus infection
IL-21 may play an important role in the pathogenesis of SSc (show CYP11A1 ELISA Kits) as a Th17 effector cytokine, and IL-21 may induce the differentiation of Th17 cells in the BLM-induced systemic sclerosis mouse model via Il21R (show IL21R ELISA Kits).
The data of this study suggested that an increase in astrocyte-derived IL-21 expression in hippocampal subregions following KA-induced seizures may have potent regulatory effects on epileptogenesis.
this study reveals a context-dependent role for IL-21 in sustaining effector phenotype CD8 (show CD8A ELISA Kits) T cells and influencing their migratory properties, accumulation, and functions.
Dysregulated development of IL-17 (show IL17A ELISA Kits)- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORgammat.
results demonstrate that, in the setting of lupus-like CD4 (show CD4 ELISA Kits) T cell-driven B cell hyperactivity, IL-21 signaling on Ag-specific donor CD8 (show CD8A ELISA Kits) T cells is critical for CTL effector maturation whereas a lack of IL-21R (show IL21R ELISA Kits) downregulates CTL responses that would otherwise limit B cell hyperactivity and autoantibody production
Gene expression analyses of angioimmunoblastic T-cell lymphoma (AITL), showed that essentially all cases expressed elevated levels of transcripts for IL21, IL21R (show IL21R ELISA Kits), and a series of genes associated with TFH cell development and function.
The results revealed that the peak expression of IL6 (show IL6 ELISA Kits) and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, interleukin-21 isoform