Browse our anti-IL4 Receptor (IL4R) Antibodies

Full name:
anti-Interleukin 4 Receptor Antibodies (IL4R)
On are 178 Interleukin 4 Receptor (IL4R) Antibodies from 22 different suppliers available. Additionally we are shipping IL4 Receptor Proteins (35) and IL4 Receptor Kits (27) and many more products for this protein. A total of 252 IL4 Receptor products are currently listed.
CD124, IL-4RA, IL4, Il4r, Il4ra, zgc:113063

Most Popular Reactivities for anti-IL4 Receptor (IL4R) Antibodies

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anti-Human IL4 Receptor Antibodies:

anti-Rat (Rattus) IL4 Receptor Antibodies:

anti-Mouse (Murine) IL4 Receptor Antibodies:

All available anti-IL4 Receptor Antibodies

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Top referenced anti-IL4 Receptor Antibodies

  1. Human Monoclonal IL4 Receptor Primary Antibody for FACS, IHC - ABIN4899803 : Boulaftali, Hess, Getz, Cholka, Stolla, Mackman, Owens, Ware, Kahn, Bergmeier: Platelet ITAM signaling is critical for vascular integrity in inflammation. in The Journal of clinical investigation 2013 (PubMed)
    Show all 15 references for 4899803

  2. Human Polyclonal IL4 Receptor Primary Antibody for WB - ABIN1944783 : Idzerda, March, Mosley, Lyman, Vanden Bos, Gimpel, Din, Grabstein, Widmer, Park: Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. in The Journal of experimental medicine 1990 (PubMed)
    Show all 5 references for 1944783

  3. Human Monoclonal IL4 Receptor Primary Antibody for FACS - ABIN4896684 : Mandruzzato, Solito, Falisi, Francescato, Chiarion-Sileni, Mocellin, Zanon, Rossi, Nitti, Bronte, Zanovello: IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 2 references for 4896684

  4. Human Monoclonal IL4 Receptor Primary Antibody for FACS - ABIN4896680 : Sindrilaru, Peters, Wieschalka, Baican, Baican, Peter, Hainzl, Schatz, Qi, Schlecht, Weiss, Wlaschek, Sunderkötter, Scharffetter-Kochanek: An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. in The Journal of clinical investigation 2011 (PubMed)
    Show all 2 references for 4896680

  5. Human Polyclonal IL4 Receptor Primary Antibody for IF, ELISA - ABIN1531667 : Loftus, Kim, Sneddon, Kalush, Brandon, Fuhrmann, Mason, Crosby, Barnstead, Cronin, Deslattes Mays, Cao, Xu, Kang, Mitchell, Eichler, Harris, Venter, Adams: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. in Genomics 1999 (PubMed)

  6. Human Monoclonal IL4 Receptor Primary Antibody for FACS - ABIN4896676 : Biancheri, Di Sabatino, Ammoscato, Facciotti, Caprioli, Curciarello, Hoque, Ghanbari, Joe-Njoku, Giuffrida, Rovedatti, Geginat, Corazza, MacDonald: Absence of a role for interleukin-13 in inflammatory bowel disease. in European journal of immunology 2014 (PubMed)

  7. Mouse (Murine) Polyclonal IL4 Receptor Primary Antibody for FACS - ABIN4898605 : Nguyen, Frye, Zbesko, Stepanovic, Hayes, Urzua, Serrano, Beach, Doyle: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. in Acta neuropathologica communications 2016 (PubMed)

More Antibodies against IL4 Receptor Interaction Partners

Cow (Bovine) Interleukin 4 Receptor (IL4R) interaction partners

  1. IL-4 (show IL4 Antibodies) may play a role in coordinating the adrenal response to inflammatory stress.

Zebrafish Interleukin 4 Receptor (IL4R) interaction partners

Human Interleukin 4 Receptor (IL4R) interaction partners

  1. Naive CD4+ Tconv cells from subjects with asthma bearing the IL4RR576 mutation show defective induction of iTreg cells and their skewing toward a TH17-like phenotype.

  2. Result showed that exposure of Peripheral Blood-Mesenchymal Stem Cells (PB-MSCs) to Noggin was associated with changes in pattern of CD29/CD184 expression. The expression profile of CD29(+/-)/CD184(-) can be suggested as a robust signature for tracing differentiation of PB-MSCs into neuronal cells.

  3. The promoter methylation levels of GATA3 (show GATA3 Antibodies), IL-4 (show IL4 Antibodies), and TGF-beta (show TGFB1 Antibodies) were significantly higher in active VKH patients than in healthy individuals

  4. results suggest that certain polymorphisms of IL4 (show IL4 Antibodies) and IL4R may affect susceptibility to gastrointestinal cancer [meta-analysis]

  5. Study indicates that endogenously expressed IL-4 (show IL4 Antibodies) and IL-4Ralpha contribute to the malignant phenotype of pancreatic cancer cells by activating diverse pro-oncogenic signaling pathways.

  6. Polymorphisms in promoter region of IL-4 (show IL4 Antibodies) but not IL-4RA genes confer susceptibility to juvenile idiopathic arthritis and may predispose individuals to adaptive immune responses.

  7. The aim of this study was to evaluate the impact of the polymorphisms within interleukin 4 (show IL4 Antibodies) (rs2243250, rs2227284), interleukin 4 receptor alpha chain (rs1805010, rs1805011) and interleukin 13 (show IL13 Antibodies) (rs20541) genes on the incidence of allergic phenotype in Polish pediatric population.

  8. IL-4 (show IL4 Antibodies) -590 and IL-4R Q551R gene polymorphisms are not associated with the susceptibility and the clinical pattern of alopecia areata in Saudi patients.

  9. investigated five SNPs (C-589T and C-33T of IL4 (show IL4 Antibodies), G+2044A of IL13 (show IL13 Antibodies), A+1902G of IL4Ralpha, and A+896G of TLR4 (show TLR4 Antibodies)) in patients with adult onset asthma to evaluate their role in manifestation and severity of asthma

  10. Essential role of endocytosis for interleukin-4-receptor-mediated JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signalling.

Horse (Equine) Interleukin 4 Receptor (IL4R) interaction partners

  1. IL4R plays a role in some cases of recurrent airway obstruction.

Mouse (Murine) Interleukin 4 Receptor (IL4R) interaction partners

  1. Data, including data from studies in transgenic/knockout mice, suggest expression of Gab1 (show GAB1 Antibodies)/Gab2 (show GAB2 Antibodies) is up-regulated in activated macrophages in pulmonary fibrosis; both Gab1 (show GAB1 Antibodies)/Gab2 (show GAB2 Antibodies) are recruited to Il4r, synergistically enhancing downstream signal amplification. (Gab1 (show GAB1 Antibodies) = growth factor receptor bound protein 2-associated protein 1 (show GAB1 Antibodies); Gab2 (show GAB2 Antibodies) = growth factor receptor bound protein 2-associated protein 2 (show GAB2 Antibodies); Il4r = interleukin-4 receptor)

  2. increased expression of IL-4Ralpha on neonatal CD11b (show ITGAM Antibodies)(+) mDCs was responsible for Th2 - biased RSV immunopathophysiology

  3. a severe asthma-associated polymorphism in the gene encoding the interleukin (IL)-4 receptor alpha chain (Il4ra(R576)) promotes conversion of induced Treg (iTreg) cells toward a T helper 17 (TH17) cell fate. This skewing is mediated by the recruitment by IL-4Ralpha(R576) of the growth-factor-receptor-bound protein 2 (GRB2 (show GRB2 Antibodies)) adaptor protein, which drives IL-17 (show IL17A Antibodies) expression by activating a pathway that involves ERK (show EPHB2 Antibodies), IL-6 (show IL6 Antibodies) an...

  4. using mice deficient for IL-4Ralpha, findings show after repeated schistosome infection, levels of regulatory IL-10 (show IL10 Antibodies) in the skin were reduced, accompanied by increased numbers of MHC-IIhigh cells and CD4 (show CD4 Antibodies)+ T cells in the skin; study highlights a mechanism through which IL-4Ralpha may regulate the immune system through the induction of IL-10 (show IL10 Antibodies) and regulation of Fas (show FAS Antibodies)/FasL (show FASL Antibodies) mediated cell death

  5. IL-4Ralpha expression on CD4 (show CD4 Antibodies)+ T cells plays a major role in the pathogenesis of chronic asthma and the regulation of allergen-specific TH17 responses, whereas acute asthmatic pathology and TH2 responses developed in the absence of IL-4Ralpha-responsive CD4 (show CD4 Antibodies)+ T cells and IL-4 (show IL4 Antibodies).

  6. Genome-wide expression of isolated Kupffer cells following pressure-controlled hemorrhage revealed a significant increase of gene expression of Cxcl10, Il4ra, Csf2rb2, Lcn2, and Gbp5, which might represent new biomarkers for early diagnosis of post-traumatic complications.

  7. Il4ra mRNA expression was significantly increased after stroke.

  8. functional synergy between Flt3 (show FLT3 Antibodies) and IL-4R signaling is critical for Stat (show STAT1 Antibodies)-mediated regulation of sterile gamma1 germ-line transcripts and CSR (show SCARA3 Antibodies) to IgG1

  9. Immunostaining and semiquantitative analysis revealed increased presence of IL4ra in the pulmonary vasculature of patients with connective tissue disease-associated PAH and Schistosoma-PAH compared with normal control subjects.

  10. data provide new insights into the molecular mechanisms governing IL-4Ralpha-induced responses, and may provide new therapeutic tools to target IL-4 (show IL4 Antibodies) in allergy and asthma

IL4 Receptor (IL4R) Antigen Profile

Antigen Summary

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with IL4 Receptor (IL4R)

  • interleukin 4 receptor (IL4R) antibody
  • interleukin 4 receptor (il4r) antibody
  • interleukin 4 receptor (LOC100220266) antibody
  • interleukin 4 receptor (Il4r) antibody
  • interleukin 4 receptor, alpha (Il4ra) antibody
  • CD124 antibody
  • IL-4RA antibody
  • IL4 antibody
  • Il4r antibody
  • Il4ra antibody
  • zgc:113063 antibody

Protein level used designations for IL4R

interleukin 4 receptor alpha chain , interleukin-4 receptor alpha chain , interleukin-4 receptor subunit alpha , interleukin 4 receptor , IL-4RA-like protein 1 , il-4alpha , interleukin 4 receptor alpha , soluble IL-4 receptor alpha , interleukin-4 receptor subunit alpha-like , IL-4 receptor subunit alpha , IL4R nirs variant 1 , IL-4R subunit alpha , IL-4R-alpha , IL-4RA , interleukin 4 receptor, alpha , interleukin 4 tv3 , interleukin 4 tv5 , interleukin-4 receptor alpha-chain , IL-4 receptor alpha chain

404154 Bos taurus
416585 Gallus gallus
454005 Pan troglodytes
489957 Canis lupus familiaris
503594 Danio rerio
705404 Macaca mulatta
100220266 Taeniopygia guttata
100412639 Callithrix jacchus
100449812 Pongo abelii
100606206 Nomascus leucogenys
3566 Homo sapiens
25084 Rattus norvegicus
397614 Sus scrofa
791252 Equus caballus
16190 Mus musculus
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