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Browse our anti-IL7R (IL7R) Antibodies

Full name:
anti-Interleukin 7 Receptor Antibodies (IL7R)
On are 370 Interleukin 7 Receptor (IL7R) Antibodies from 27 different suppliers available. Additionally we are shipping IL7R Proteins (28) and IL7R Kits (25) and many more products for this protein. A total of 439 IL7R products are currently listed.
CD127, CDW127, IL-7R-alpha, IL-7RA, IL-7Ralpha, IL7R, IL7RA, ILRA
list all antibodies Gene Name GeneID UniProt
IL7R 16197 P16872
IL7R 3575 P16871
IL7R 294797  

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Most Popular Reactivities for anti-IL7R (IL7R) Antibodies

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anti-Mouse (Murine) IL7R Antibodies:

anti-Human IL7R Antibodies:

anti-Rat (Rattus) IL7R Antibodies:

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Top referenced anti-IL7R Antibodies

  1. Mouse (Murine) Monoclonal IL7R Primary Antibody for BR, FACS - ABIN1176855 : Akashi, Kondo, Weissman: Role of interleukin-7 in T-cell development from hematopoietic stem cells. in Immunological reviews 1999 (PubMed)
    Show all 9 references for ABIN1176855

  2. Mouse (Murine) Monoclonal IL7R Primary Antibody for FACS, ICFC - ABIN2657326 : Huster, Busch, Schiemann, Linkemann, Kerksiek, Wagner, Busch: Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 9 references for ABIN2657326

  3. Mouse (Murine) Monoclonal IL7R Primary Antibody for ICFC - ABIN2660269 : Pillai, Torok-Storb, Iwata: Expression and function of IL-7 receptors in marrow stromal cells. in Leukemia & lymphoma 2004 (PubMed)
    Show all 5 references for ABIN2660269

  4. Mouse (Murine) Monoclonal IL7R Primary Antibody for ELISA (Capture) - ABIN2657626 : Sudo, Nishikawa, Ohno, Akiyama, Tamakoshi, Yoshida, Nishikawa: Expression and function of the interleukin 7 receptor in murine lymphocytes. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 5 references for ABIN2657626

  5. Mouse (Murine) Polyclonal IL7R Primary Antibody for IP, ELISA - ABIN233847 : Osborne, Dhanji, Snow, Priatel, Ma, Miners, Teh, Goldsmith, Abraham: Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice. in The Journal of experimental medicine 2007 (PubMed)

  6. Human Polyclonal IL7R Primary Antibody for ELISA, WB - ABIN1532692 : Goodwin, Friend, Ziegler, Jerzy, Falk, Gimpel, Cosman, Dower, March, Namen: Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. in Cell 1990 (PubMed)

More Antibodies against IL7R Interaction Partners

Rhesus Monkey Interleukin 7 Receptor (IL7R) interaction partners

  1. We found that the percentage of T cells expressing IL-7R was significantly lower in both CD4(+) and CD8(+) T cell subsets blood and tissues in SIV-infected macaques than in healthy animals.

  2. The CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)+CD127low phenotype is found to be characteristic of regulatory cells found in mice and in rhesus macaques.

Mouse (Murine) Interleukin 7 Receptor (IL7R) interaction partners

  1. results suggest that LNK (show SH2B3 Antibodies) suppresses IL-7R/JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling to restrict pro-/pre-B progenitor expansion and leukemia development, providing a pathogenic mechanism and a potential therapeutic approach for B-ALLs with LNK (show SH2B3 Antibodies) mutations.

  2. The IL-7R plays an important role in the induction of HFD-induced adipogenesis and insulin (show INS Antibodies) resistance in mice.

  3. This work demonstrates that the CNS1 element controls IL-7Ralpha expression and maintenance of peripheral T cells, suggesting differential regulation of IL-7Ralpha expression between central and peripheral lymphoid organs.

  4. Data show the contribution of IL-23/IL-23 (show IL23A Antibodies) receptor (show IL23R Antibodies) and IL-7/IL-7 (show IL7 Antibodies) receptor signaling in Th17 and Th1 (show HAND1 Antibodies) cell dynamics during experimental autoimmune encephalomyelitis (EAE).

  5. Inhibition of the IL-7 (show IL7 Antibodies) receptor inhibits tumor growth in murine models of melanoma.

  6. The combined loss of Gads (show GRAP2 Antibodies) and CD127 reveals a novel function of Gads (show GRAP2 Antibodies) prior to T cell receptor beta expression

  7. Results provided evidence that IL-7 (show IL7 Antibodies)/IL-7R induce VEGF-D (show Figf Antibodies) upregulation and promote lymphangiogenesis via c-Fos/c-Jun (show JUN Antibodies) pathway in lung cancer.

  8. data suggest that IL-7Ralpha Tyr (show TYR Antibodies)(449) was essential for IL-7Ralpha signaling in bone marrow B cell development and survival.

  9. The development and survival but not function of follicular B cells is dependent on IL-7Ralpha Tyr449 signaling.

  10. interleukin-7 receptor mutants induce early T cell precursor acute lymphoblastic leukemia by the block of thymocyte differentiation at the double negative 2 stage at which myeloid lineage and T lymphocyte developmental potential coexist.

Human Interleukin 7 Receptor (IL7R) interaction partners

  1. Immunophenotyping with CD135 (show FLT3 Antibodies) and CD117 predicts the FLT3 (show FLT3 Antibodies), IL-7R and TLX3 (show TLX3 Antibodies) gene mutations in childhood T-cell acute leukemia.

  2. A decrease of CD4 (show CD4 Antibodies)(+) CD25 (show IL2RA Antibodies)(+) CD127(low) FoxP3 (show FOXP3 Antibodies)(+) regulatory T cells with impaired suppressive function had been found in untreated ulcerative colitis patients.

  3. results suggest that LNK (show SH2B3 Antibodies) suppresses IL-7R/JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling to restrict pro-/pre-B progenitor expansion and leukemia development, providing a pathogenic mechanism and a potential therapeutic approach for B-ALLs with LNK (show SH2B3 Antibodies) mutations.

  4. Pretransplant recipient circulating CD4 (show CD4 Antibodies)+CD127lo/-TNFR2 (show TNFRSF1B Antibodies)+ Treg cell is potentially a simpler alternative to Treg cell function as a pretransplant recipient immune marker for acute kidney injury.

  5. CD4 (show CD4 Antibodies)+CD45RO+CD25 (show IL2RA Antibodies)-/lowCD127+: CD4 (show CD4 Antibodies)+CD45RO+CD25hiCD127-/low ratio in peripheral blood indicates heart transplant recipients at risk for cardiac allograft vasculopathy.

  6. Data suggest that the lack of IL-7 receptor alpha chain (IL7Ralpha) expression, associated with hypermethylation of the IL7R promoter, in T cells restricts T-cell development in Schimke immuno-osseous dysplasia (SIOD) patients.

  7. Substitution of the first 10 Nterminal residues or deletion of residues 17-21 prevented Tat (show TAT Antibodies) from interacting with and down regulating CD127 from the cell surface.

  8. In view of the important role IL-7 (show IL7 Antibodies) plays in lymphocyte proliferation, homeostasis and survival, down regulation of CD127 by Tat (show TAT Antibodies) likely plays a central role in immune dysregulation and CD4 (show CD4 Antibodies) T-cell decline

  9. This study then provides evidence that soluble factor(s) are responsible for low CD127 expression on circulating CD8 (show CD8A Antibodies) T-cells in HIV+ individuals and further implicates Tat (show TAT Antibodies) in suppressing this receptor essential to CD8 (show CD8A Antibodies) T-cell proliferation and function.

  10. Findings indicate that IL7 (show IL7 Antibodies) receptor (IL7R) and c-myc (show MYC Antibodies) expression as intrinsic biomarkers that can predict the fate of CD8 (show CD8A Antibodies)+ T effector cells after adoptive transfer.

Horse (Equine) Interleukin 7 Receptor (IL7R) interaction partners

  1. Data show a statistically significant association between a single nucleotide polymorphism (SNP) within the interleukin 7 receptor-encoding gene (IL7R) with high R. equi burden.

IL7R Antigen Profile

Antigen Summary

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).

Alternative names and synonyms associated with IL7R

  • interleukin 7 receptor (IL7R) antibody
  • interleukin 7 receptor (LOC100226205) antibody
  • interleukin 7 receptor (Il7r) antibody
  • CD127 antibody
  • CDW127 antibody
  • IL-7R-alpha antibody
  • IL-7RA antibody
  • IL-7Ralpha antibody
  • IL7R antibody
  • IL7RA antibody
  • ILRA antibody

Protein level used designations for IL7R

interleukin 7 receptor , interleukin-7 receptor subunit alpha-like , IL-7 receptor alpha chain , IL-7 receptor subunit alpha , IL-7R subunit alpha , IL-7R-alpha , IL-7RA , interleukin 7 receptor alpha chain , interleukin-7 receptor subunit alpha , CD127 antigen , interleukin 7 receptor isoform H5-6 , Interleukin-7 receptor subunit alpha-like protein , Interleukin-7 receptor subunit alpha

699869 Macaca mulatta
100226205 Taeniopygia guttata
100343726 Oryctolagus cuniculus
100461835 Pongo abelii
100583768 Nomascus leucogenys
16197 Mus musculus
3575 Homo sapiens
294797 Rattus norvegicus
100034169 Equus caballus
612582 Canis lupus familiaris
521554 Bos taurus
100397720 Callithrix jacchus
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