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Browse our anti-IL7R (IL7R) Antibodies

Full name:
anti-Interleukin 7 Receptor Antibodies (IL7R)
On are 387 Interleukin 7 Receptor (IL7R) Antibodies from 28 different suppliers available. Additionally we are shipping IL7R Proteins (31) and IL7R Kits (27) and many more products for this protein. A total of 461 IL7R products are currently listed.
CD127, CDW127, IL-7R-alpha, IL-7RA, IL-7Ralpha, IL7R, IL7RA, ILRA
list all antibodies Gene Name GeneID UniProt
IL7R 16197 P16872
IL7R 3575 P16871
IL7R 294797  

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Most Popular Reactivities for anti-IL7R (IL7R) Antibodies

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anti-Mouse (Murine) IL7R Antibodies:

anti-Human IL7R Antibodies:

anti-Rat (Rattus) IL7R Antibodies:

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Top referenced anti-IL7R Antibodies

  1. Mouse (Murine) Monoclonal IL7R Primary Antibody for BR, FACS - ABIN1176855 : Akashi, Kondo, Weissman: Role of interleukin-7 in T-cell development from hematopoietic stem cells. in Immunological reviews 1999 (PubMed)
    Show all 9 references for ABIN1176855

  2. Human Monoclonal IL7R Primary Antibody for FACS, WB - ABIN4900541 : Hoe, McKay, Schibeci, Gandhi, Heard, Stewart, Booth: Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN4900541

  3. Human Monoclonal IL7R Primary Antibody for FACS - ABIN610367 : Chapman, An, Barton, Jahn: SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils. in The Journal of biological chemistry 1994 (PubMed)
    Show all 3 references for ABIN610367

  4. Human Monoclonal IL7R Primary Antibody for FACS - ABIN4897915 : Pillai, Ortega, Wang, Karandikar: Transient regulatory T-cells: a state attained by all activated human T-cells. in Clinical immunology (Orlando, Fla.) 2007 (PubMed)
    Show all 3 references for ABIN4897915

  5. Human Monoclonal IL7R Primary Antibody for FACS - ABIN4897923 : Fluur, De Milito, Fry, Vivar, Eidsmo, Atlas, Federici, Matarrese, Logozzi, Rajnavölgyi, Mackall, Fais, Chiodi, Rethi: Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 references for ABIN4897923

  6. Human Monoclonal IL7R Primary Antibody for ELISA - ABIN1997873 : Vranjkovic, Crawley, Gee, Kumar, Angel: IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells. in International immunology 2007 (PubMed)
    Show all 2 references for ABIN1997873

  7. Mouse (Murine) Polyclonal IL7R Primary Antibody for IP, ELISA - ABIN233847 : Osborne, Dhanji, Snow, Priatel, Ma, Miners, Teh, Goldsmith, Abraham: Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice. in The Journal of experimental medicine 2007 (PubMed)

  8. Human Polyclonal IL7R Primary Antibody for ELISA, WB - ABIN1532692 : Goodwin, Friend, Ziegler, Jerzy, Falk, Gimpel, Cosman, Dower, March, Namen: Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. in Cell 1990 (PubMed)

More Antibodies against IL7R Interaction Partners

Rhesus Monkey Interleukin 7 Receptor (IL7R) interaction partners

  1. We found that the percentage of T cells expressing IL-7R was significantly lower in both CD4(+) and CD8(+) T cell subsets blood and tissues in SIV-infected macaques than in healthy animals.

  2. The CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)+CD127low phenotype is found to be characteristic of regulatory cells found in mice and in rhesus macaques.

Mouse (Murine) Interleukin 7 Receptor (IL7R) interaction partners

  1. These studies provide in vivo evidence that IL-7Ralpha signals positively regulate normal human B-cell production and proliferation beyond the fetal period and suggest that TSLP (show TSLP Antibodies) can replace IL-7 (show IL7 Antibodies) in providing these signals.

  2. Bcl6 (show BCL6 Antibodies) promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a (show STAT5A Antibodies) axis.

  3. results suggest that LNK (show SH2B3 Antibodies) suppresses IL-7R/JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling to restrict pro-/pre-B progenitor expansion and leukemia development, providing a pathogenic mechanism and a potential therapeutic approach for B-ALLs with LNK (show SH2B3 Antibodies) mutations.

  4. The IL-7R plays an important role in the induction of HFD-induced adipogenesis and insulin (show INS Antibodies) resistance in mice.

  5. This work demonstrates that the CNS1 element controls IL-7Ralpha expression and maintenance of peripheral T cells, suggesting differential regulation of IL-7Ralpha expression between central and peripheral lymphoid organs.

  6. Data show the contribution of IL-23/IL-23 (show IL23A Antibodies) receptor (show IL23R Antibodies) and IL-7/IL-7 (show IL7 Antibodies) receptor signaling in Th17 and Th1 (show HAND1 Antibodies) cell dynamics during experimental autoimmune encephalomyelitis (EAE).

  7. Inhibition of the IL-7 (show IL7 Antibodies) receptor inhibits tumor growth in murine models of melanoma.

  8. The combined loss of Gads (show GRAP2 Antibodies) and CD127 reveals a novel function of Gads (show GRAP2 Antibodies) prior to T cell receptor beta expression

  9. Results provided evidence that IL-7 (show IL7 Antibodies)/IL-7R induce VEGF-D (show Figf Antibodies) upregulation and promote lymphangiogenesis via c-Fos/c-Jun (show JUN Antibodies) pathway in lung cancer.

  10. data suggest that IL-7Ralpha Tyr (show TYR Antibodies)(449) was essential for IL-7Ralpha signaling in bone marrow B cell development and survival.

Human Interleukin 7 Receptor (IL7R) interaction partners

  1. These studies provide in vivo evidence that IL-7Ralpha signals positively regulate normal human B-cell production and proliferation beyond the fetal period and suggest that TSLP (show TSLP Antibodies) can replace IL-7 (show IL7 Antibodies) in providing these signals.

  2. Study showed that a genetic variant in the 5' UTR (show UTS2R Antibodies) of DDX39B (show DDX39 Antibodies) reduces translation of DDX39B (show DDX39 Antibodies) mRNAs and increases multiple sclerosis (MS) risk. Importantly, this DDX39B (show DDX39 Antibodies) variant showed strong genetic & functional epistasis with allelic variants in IL7R exon 6; study establishes the occurrence of biological epistasis in humans & provides mechanistic insight into the regulation of IL7R exon 6 splicing & its impact on MS risk.

  3. study identifies casein kinase 2 as a major player in the effects of interleukin-7 (show IL7 Antibodies) and interleukin-7 receptor in T-cell acute lymphoblastic leukemia

  4. CD45RA distinguishes CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)+CD127-/low TSDR demethylated regulatory T cell subpopulations with differential stability and susceptibility to tacrolimus-mediated immunosuppression.

  5. In summary, our study demonstrates that IL-7 (show IL7 Antibodies)/IL-7R axis promotes the invasion and migration of prostate cancer cells, through activation of AKT (show AKT1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway and upregulation of MMP-3 (show MMP3 Antibodies) and MMP-7 (show MMP7 Antibodies) expression

  6. Meta-analysis demonstrated that the IL7R T244I polymorphism was associated with susceptibility to multiple sclerosis

  7. This study suggested that the IL7R C allele was associated with an increased risk of MS and larger-scale studies of populations are needed to explore the roles played by the IL7R T244I polymorphism during the pathogenesis of multiple sclerosis.

  8. the variant of IL-7RA (rs6897932) was associated with NMO especially NMO-IgG positive patients while the variant of IL-7 (show IL7 Antibodies) (rs1520333) with MS patients.

  9. this study shows that in human CD8 (show CD8A Antibodies) T cells that IL-7 (show IL7 Antibodies) binding to its receptor induces CD127 internalization via clathrin-mediated endocytosis, transport of the receptor from early to late endosomes and ultimately degradation of CD127 by the proteasome.

  10. Immunophenotyping with CD135 (show FLT3 Antibodies) and CD117 predicts the FLT3 (show FLT3 Antibodies), IL-7R and TLX3 (show TLX3 Antibodies) gene mutations in childhood T-cell acute leukemia.

Horse (Equine) Interleukin 7 Receptor (IL7R) interaction partners

  1. Data show a statistically significant association between a single nucleotide polymorphism (SNP) within the interleukin 7 receptor-encoding gene (IL7R) with high R. equi burden.

IL7R Antigen Profile

Antigen Summary

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).

Alternative names and synonyms associated with IL7R

  • interleukin 7 receptor (IL7R) antibody
  • interleukin 7 receptor (LOC100226205) antibody
  • interleukin 7 receptor (Il7r) antibody
  • CD127 antibody
  • CDW127 antibody
  • IL-7R-alpha antibody
  • IL-7RA antibody
  • IL-7Ralpha antibody
  • IL7R antibody
  • IL7RA antibody
  • ILRA antibody

Protein level used designations for IL7R

interleukin 7 receptor , interleukin-7 receptor subunit alpha-like , IL-7 receptor alpha chain , IL-7 receptor subunit alpha , IL-7R subunit alpha , IL-7R-alpha , IL-7RA , interleukin 7 receptor alpha chain , interleukin-7 receptor subunit alpha , CD127 antigen , interleukin 7 receptor isoform H5-6 , Interleukin-7 receptor subunit alpha-like protein , Interleukin-7 receptor subunit alpha

699869 Macaca mulatta
100226205 Taeniopygia guttata
100343726 Oryctolagus cuniculus
100461835 Pongo abelii
100583768 Nomascus leucogenys
16197 Mus musculus
3575 Homo sapiens
294797 Rattus norvegicus
100034169 Equus caballus
612582 Canis lupus familiaris
521554 Bos taurus
100397720 Callithrix jacchus
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