Browse our anti-IL7R (IL7R) Antibodies

Full name:
anti-Interleukin 7 Receptor Antibodies (IL7R)
On www.antibodies-online.com are 398 Interleukin 7 Receptor (IL7R) Antibodies from 30 different suppliers available. Additionally we are shipping IL7R Proteins (31) and IL7R Kits (28) and many more products for this protein. A total of 473 IL7R products are currently listed.
Synonyms:
CD127, CDW127, IL-7R-alpha, IL-7RA, IL-7Ralpha, IL7R, IL7RA, ILRA
list all antibodies Gene Name GeneID UniProt
IL7R 16197 P16872
IL7R 3575 P16871
IL7R 294797  

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Most Popular Reactivities for anti-IL7R (IL7R) Antibodies

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anti-Mouse (Murine) IL7R Antibodies:

anti-Human IL7R Antibodies:

anti-Rat (Rattus) IL7R Antibodies:

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Top referenced anti-IL7R Antibodies

  1. Mouse (Murine) Monoclonal IL7R Primary Antibody for BR, FACS - ABIN1176855 : Akashi, Kondo, Weissman: Role of interleukin-7 in T-cell development from hematopoietic stem cells. in Immunological reviews 1999 (PubMed)
    Show all 9 references for 1176855

  2. Human Monoclonal IL7R Primary Antibody for FACS, WB - ABIN4900541 : Hoe, McKay, Schibeci, Gandhi, Heard, Stewart, Booth: Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for 4900541

  3. Human Monoclonal IL7R Primary Antibody for FACS - ABIN610367 : Chapman, An, Barton, Jahn: SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils. in The Journal of biological chemistry 1994 (PubMed)
    Show all 3 references for 610367

  4. Human Monoclonal IL7R Primary Antibody for FACS - ABIN4897915 : Pillai, Ortega, Wang, Karandikar: Transient regulatory T-cells: a state attained by all activated human T-cells. in Clinical immunology (Orlando, Fla.) 2007 (PubMed)
    Show all 3 references for 4897915

  5. Human Monoclonal IL7R Primary Antibody for FACS - ABIN4897923 : Fluur, De Milito, Fry, Vivar, Eidsmo, Atlas, Federici, Matarrese, Logozzi, Rajnavölgyi, Mackall, Fais, Chiodi, Rethi: Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 references for 4897923

  6. Human Monoclonal IL7R Primary Antibody for ELISA - ABIN1997873 : Vranjkovic, Crawley, Gee, Kumar, Angel: IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells. in International immunology 2007 (PubMed)
    Show all 2 references for 1997873

  7. Mouse (Murine) Polyclonal IL7R Primary Antibody for IP, ELISA - ABIN233847 : Osborne, Dhanji, Snow, Priatel, Ma, Miners, Teh, Goldsmith, Abraham: Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice. in The Journal of experimental medicine 2007 (PubMed)

  8. Human Polyclonal IL7R Primary Antibody for ELISA, WB - ABIN1532692 : Goodwin, Friend, Ziegler, Jerzy, Falk, Gimpel, Cosman, Dower, March, Namen: Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. in Cell 1990 (PubMed)

More Antibodies against IL7R Interaction Partners

Rhesus Monkey Interleukin 7 Receptor (IL7R) interaction partners

  1. We found that the percentage of T cells expressing IL-7R was significantly lower in both CD4(+) and CD8(+) T cell subsets blood and tissues in SIV-infected macaques than in healthy animals.

  2. The CD4 (show CD4 Antibodies)+CD25 (show IL2RA Antibodies)+CD127low phenotype is found to be characteristic of regulatory cells found in mice and in rhesus macaques.

Mouse (Murine) Interleukin 7 Receptor (IL7R) interaction partners

  1. results indicate that the induction of IL-7Ralpha expression on dendritic cells (DCs) is critical for thymic stromal lymphopoietin (show TSLP Antibodies) responsiveness and that IL-4 (show IL4 Antibodies) can upregulate IL-7Ralpha on DCs.

  2. IL-7RA role in hematopoiesis and development of the lympho-myeloid progenitors in the developing fetal liver

  3. These studies provide in vivo evidence that IL-7Ralpha signals positively regulate normal human B-cell production and proliferation beyond the fetal period and suggest that TSLP (show TSLP Antibodies) can replace IL-7 (show IL7 Antibodies) in providing these signals.

  4. Bcl6 (show BCL6 Antibodies) promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a (show STAT5A Antibodies) axis.

  5. results suggest that LNK (show SH2B3 Antibodies) suppresses IL-7R/JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling to restrict pro-/pre-B progenitor expansion and leukemia development, providing a pathogenic mechanism and a potential therapeutic approach for B-ALLs with LNK (show SH2B3 Antibodies) mutations.

  6. The IL-7R plays an important role in the induction of HFD-induced adipogenesis and insulin (show INS Antibodies) resistance in mice.

  7. This work demonstrates that the CNS1 element controls IL-7Ralpha expression and maintenance of peripheral T cells, suggesting differential regulation of IL-7Ralpha expression between central and peripheral lymphoid organs.

  8. Data show the contribution of IL-23/IL-23 (show IL23A Antibodies) receptor (show IL23R Antibodies) and IL-7/IL-7 (show IL7 Antibodies) receptor signaling in Th17 and Th1 (show HAND1 Antibodies) cell dynamics during experimental autoimmune encephalomyelitis (EAE).

  9. Inhibition of the IL-7 (show IL7 Antibodies) receptor inhibits tumor growth in murine models of melanoma.

  10. The combined loss of Gads (show GRAP2 Antibodies) and CD127 reveals a novel function of Gads (show GRAP2 Antibodies) prior to T cell receptor beta expression

Human Interleukin 7 Receptor (IL7R) interaction partners

  1. Tuberculosis patients had lower soluble IL-7R and higher IL-7 (show IL7 Antibodies) plasma concentrations as compared to healthy contacts.

  2. CD56 (show NCAM1 Antibodies)(bright) NK IL-7Ralpha expression negatively associates with HCV level, and IL-7 (show IL7 Antibodies)-induced NK function is impaired during HCV and HIV infections

  3. IL-7 (show IL7 Antibodies) has a role inducing epitope masking of gammac protein in IL-7 (show IL7 Antibodies) receptor signaling complex

  4. The results of this study showed that IL-17 (show IL17A Antibodies) receptor (IL-17R) were clearly up regulated in mesial temporal lobe epilepsy at both mRNA and protein levels, compared with control.

  5. the coding regions of 17 genes involved in the regulation of the immune response were determined by massive parallel sequencing. The analysis revealed 39 nonsynonymous SNPs that lead to amino acid substitutions, including the following informative genetic markers: PTPN22 (show PTPN22 Antibodies) c.1858C>T (rs2476601), TLR4 (show TLR4 Antibodies) c.896A>G (rs4986790) and TLR4 (show TLR4 Antibodies) c.1196C>T (rs4986791), IL7R c.197T>C (rs1494555) and IL7R c.412G>A (rs1494558).

  6. The interleukin-7 receptor alpha (IL-7Ralpha) signaling pathways are prime therapeutic targets because these pathways harbor genetic aberrations in both T-cell ALL and B-cell precursor ALL. Therapeutic targeting of the IL-7Ralpha signaling pathways may lead to improved outcomes in a subset of patients.

  7. Therefore, generalized CD8 (show CD8A Antibodies)+ T-cell impairment in HCV infection is characterized, in part, by impaired IL-7 (show IL7 Antibodies)-mediated signalling and survival, independent of CD127 expression. This impairment is more pronounced in the liver and may be associated with an increased potential for apoptosis. This generalized CD8 (show CD8A Antibodies)+ T-cell impairment represents an important immune dysfunction in chronic HCV infection that may alter patient health.

  8. These studies provide in vivo evidence that IL-7Ralpha signals positively regulate normal human B-cell production and proliferation beyond the fetal period and suggest that TSLP (show TSLP Antibodies) can replace IL-7 (show IL7 Antibodies) in providing these signals.

  9. Study showed that a genetic variant in the 5' UTR (show UTS2R Antibodies) of DDX39B (show DDX39 Antibodies) reduces translation of DDX39B (show DDX39 Antibodies) mRNAs and increases multiple sclerosis (MS) risk. Importantly, this DDX39B (show DDX39 Antibodies) variant showed strong genetic & functional epistasis with allelic variants in IL7R exon 6; study establishes the occurrence of biological epistasis in humans & provides mechanistic insight into the regulation of IL7R exon 6 splicing & its impact on MS risk.

  10. study identifies casein kinase 2 as a major player in the effects of interleukin-7 (show IL7 Antibodies) and interleukin-7 receptor in T-cell acute lymphoblastic leukemia

Horse (Equine) Interleukin 7 Receptor (IL7R) interaction partners

  1. Data show a statistically significant association between a single nucleotide polymorphism (SNP) within the interleukin 7 receptor-encoding gene (IL7R) with high R. equi burden.

IL7R Antigen Profile

Antigen Summary

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).

Alternative names and synonyms associated with IL7R

  • interleukin 7 receptor (IL7R) antibody
  • interleukin 7 receptor (LOC100226205) antibody
  • interleukin 7 receptor (Il7r) antibody
  • CD127 antibody
  • CDW127 antibody
  • IL-7R-alpha antibody
  • IL-7RA antibody
  • IL-7Ralpha antibody
  • IL7R antibody
  • IL7RA antibody
  • ILRA antibody

Protein level used designations for IL7R

interleukin 7 receptor , interleukin-7 receptor subunit alpha-like , IL-7 receptor alpha chain , IL-7 receptor subunit alpha , IL-7R subunit alpha , IL-7R-alpha , IL-7RA , interleukin 7 receptor alpha chain , interleukin-7 receptor subunit alpha , CD127 antigen , interleukin 7 receptor isoform H5-6 , Interleukin-7 receptor subunit alpha-like protein , Interleukin-7 receptor subunit alpha

GENE ID SPECIES
699869 Macaca mulatta
100226205 Taeniopygia guttata
100343726 Oryctolagus cuniculus
100461835 Pongo abelii
100583768 Nomascus leucogenys
16197 Mus musculus
3575 Homo sapiens
294797 Rattus norvegicus
100034169 Equus caballus
612582 Canis lupus familiaris
521554 Bos taurus
100397720 Callithrix jacchus
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