Browse our anti-Exportin 1, CRM1 Homolog (Yeast) (XPO1) Antibodies

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anti-Exportin 1, CRM1 Homolog (Yeast) Antibodies (XPO1)
On are 99 Exportin 1, CRM1 Homolog (Yeast) (XPO1) Antibodies from 22 different suppliers available. Additionally we are shipping Exportin 1, CRM1 Homolog (Yeast) Kits (8) and Exportin 1, CRM1 Homolog (Yeast) Proteins (3) and many more products for this protein. A total of 118 Exportin 1, CRM1 Homolog (Yeast) products are currently listed.
18.m06600, AA420417, CG13387, crm1, dCRM1, DDBDRAFT_0183812, DDBDRAFT_0234066, DDB_0183812, DDB_0234066, Dmel\\CG13387, emb, Exp1, exportin-1, l(2)k16715, LOC100220104, Xpo, XPO-1, Xpo1

Most Popular Reactivities for anti-Exportin 1, CRM1 Homolog (Yeast) (XPO1) Antibodies

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All available anti-Exportin 1, CRM1 Homolog (Yeast) Antibodies

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Top referenced anti-Exportin 1, CRM1 Homolog (Yeast) Antibodies

  1. Chicken Monoclonal XPO1 Primary Antibody for IF, WB - ABIN968674 : Boer, Bonten-Surtel, Grosveld: Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis. in Molecular and cellular biology 1998 (PubMed)
    Show all 6 references for 968674

  2. Human Polyclonal XPO1 Primary Antibody for ICC, IF - ABIN256674 : von Knethen, Tzieply, Jennewein, Brüne: Casein-kinase-II-dependent phosphorylation of PPARgamma provokes CRM1-mediated shuttling of PPARgamma from the nucleus to the cytosol. in Journal of cell science 2010 (PubMed)
    Show all 4 references for 256674

  3. Human Polyclonal XPO1 Primary Antibody for FACS, IHC (p) - ABIN390636 : Dong, Biswas, Chook: Structural basis for assembly and disassembly of the CRM1 nuclear export complex. in Nature structural & molecular biology 2009 (PubMed)
    Show all 2 references for 390636

  4. Human Polyclonal XPO1 Primary Antibody for EIA, WB - ABIN453470 : Shen, Wang, Zhao, Zou, Sun, Cheng: Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis. in Neurosurgery 2009 (PubMed)
    Show all 2 references for 453470

  5. Cow (Bovine) Polyclonal XPO1 Primary Antibody for IHC, IHC (p) - ABIN4300538 : Bagheri, Badduke, Qiao, Colnaghi, Abramowicz, Alcantara, Dunham, Wen, Wildin, Nowaczyk, Eichmeyer, Lehman, Maranda, Martell, Shan, Lewis, ODriscoll, Gregory-Evans, Rajcan-Separovic: Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis. in JCI insight 2016 (PubMed)

  6. Cow (Bovine) Polyclonal XPO1 Primary Antibody for IHC, WB - ABIN2778850 : Cheong, Gunaratnam, Hsu: CRM1-mediated nuclear export is required for 26 S proteasome-dependent degradation of the TRIP-Br2 proto-oncoprotein. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against Exportin 1, CRM1 Homolog (Yeast) Interaction Partners

Fruit Fly (Drosophila melanogaster) Exportin 1, CRM1 Homolog (Yeast) (XPO1) interaction partners

  1. Nuclear export of TIS11 (show ZFP36 Antibodies) proteins is mediated by CRM1 through diverging nuclear export signals, while their nuclear import mechanism may rely on a highly conserved signal whose activity is negatively regulated by ZnF2 (show ZNF2 Antibodies) folding.

  2. HPO (show GFER Antibodies) promotes the translocation of SD to the cytoplasm in a CRM1-dependent manner

  3. Exportin-1 is a nuclear export receptor for expanded polyQ containing proteins.

  4. Nuclear localization of the ecdysteroid receptor (EcR) is increased in HeLa cells if exportin-1 (CRM1) is knocked down by siRNA against exportin.

  5. Data show that downregulation of YAN involves CRM1-mediated nuclear export, and that MAE is involved in MAPK (show MAPK1 Antibodies) phosphorylationof YAN.

  6. A major function of DNup88 is to anchor DNup214 (show NUP214 Antibodies) and CRM1 on the nuclear envelope and thereby attenuate NES (show NES Antibodies)-mediated nuclear export.

  7. Phosphorylation of Yan favors Crm1 in this competition and counteracts inhibition of nuclear export by Mae

  8. two functional nuclear export signals are in the Sima basic helix-loop-helix (bHLH) domain and promote CRM1-dependent nuclear export

Human Exportin 1, CRM1 Homolog (Yeast) (XPO1) interaction partners

  1. Data show that the cytoplasmic localization of promyelocytic leukaemia (PML (show PML Antibodies)) is mediated by its nuclear export in a chromosomal maintenance 1 (CRM1)-dependent manner.

  2. CRM1 and CDK5 (show CDK5 Antibodies) co-expression was an independent prognostic factors for gastric cancer (GC). Combined CRM1 and CDK5 (show CDK5 Antibodies) expression could provide a prognostic model for overall survival of GC.

  3. Anti-tumor activity of selective exportin 1 inhibitors is enhanced in non-Hodgkin lymphoma through combination with mTOR (show FRAP1 Antibodies) inhibitor and dexamethasone.

  4. the functional consequences of a recurrent cancer-related mutation, which targets a residue near CRM1 NES (show NES Antibodies)-binding cleft, was investigated.

  5. we characterized the biologic significance of CRM1 in the context of Ewing sarcoma and determined the therapeutic merit of CRM1 inhibition for this malignancy.

  6. XPO1 E571K mutation represents a genetic hallmark of the PMBL subtype and serves as a new relevant PMBL biomarker. SINE compounds appear active for both mutated and wild-type protein

  7. CRM1 mediates nuclear export of influenza A nucleoprotein.

  8. the detection of the XPO1 E571K mutation in biopsy and plasma cell-free DNA by digital PCR may be used as a novel biomarker in classical Hodgkin lymphoma for both diagnosis and minimal residual disease, and pinpoints a crucial role of XPO1 in classical Hodgkin lymphoma pathogenesis.

  9. The study demonstrated the association of NUP98 (show NUP98 Antibodies)-IQCG with CRM1, and found that NUP98 (show NUP98 Antibodies)-IQCG expression inhibits the CRM1-mediated nuclear export of p65 (show GORASP1 Antibodies) and enhances the transcriptional activity of nuclear factor-kappaB. Moreover, IQCG could be entrapped in the nucleus by NUP98 (show NUP98 Antibodies)-IQCG, and the fusion protein interacts with calmodulin (show CALM1 Antibodies) via the IQ motif in a calcium-independent manner.

  10. XPO1 inhibition has downstream effects on the 3D nuclear organization of the genome.

Xenopus laevis Exportin 1, CRM1 Homolog (Yeast) (XPO1) interaction partners

  1. CRM1 binds to Axin (show AXIN1 Antibodies) in the presence of RanGTP

Mouse (Murine) Exportin 1, CRM1 Homolog (Yeast) (XPO1) interaction partners

  1. Data show that administration of a single dose of selinexor bound Exportin 1 (XPO1/CRM1) for minimally 72 hours both in vitro and in vivo.

  2. These results suggest a model wherein HIV-1 Rev-associated nuclear export signals cooperate to regulate the number or quality of CRM1's interactions with viral Rev/RRE ribonucleoprotein complexes in the nucleus.

  3. map the nuclear import and export signals of Dp71d by truncation and point mutant analysis, showing for the first time Dp71d shuttles between nucleus and cytoplasm mediated by conventional nuclear transporters, importin (show KPNA4 Antibodies) (IMP (show BRAP Antibodies)) alpha/beta and the exportin CRM1

  4. AKT3 (show AKT3 Antibodies) controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1.

  5. A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 (show NEUROG3 Antibodies) in neurons.

  6. Bioavailable CRM1 inhibitor KPT-251 significantly inhibited renal cell carcinoma (show MOK Antibodies) growth in vivo with the expected on target effects and no obvious toxicity.

  7. CRM1 augments production of infectious human and feline immunodeficiency viruses from murine cells

  8. CaMKI (show CAMK1 Antibodies) vies with CRM1/exportin 1 for access to a nuclear export signal, and assembly of a CaMKI (show CAMK1 Antibodies)-14-3-3 zeta (show YWHAZ Antibodies)-CCTalpha (show PCYT1A Antibodies) complex is a key effector mechanism that drives nuclear CCTalpha (show PCYT1A Antibodies) translocation.

  9. Transcription-independent role of Bach1 (show BACH1 Antibodies) in mitosis through a nuclear exporter Crm1-dependent mechanism.

  10. CRM1 protein-mediated regulation of nuclear clusterin (show CLU Antibodies) (nCLU), an ionizing radiation-stimulated, Bax (show BAX Antibodies)-dependent pro-death factor

Exportin 1, CRM1 Homolog (Yeast) (XPO1) Antigen Profile

Antigen Summary

The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Alternative names and synonyms associated with Exportin 1, CRM1 Homolog (Yeast) (XPO1)

  • embargoed (emb) antibody
  • exportin 1 (cgd3_3060) antibody
  • exportin 1 (Tc00.1047053511725.150) antibody
  • exportin 1 (Tb11.01.5940) antibody
  • exportin 1 (BBOV_II007220) antibody
  • exportin 1 (LmjF32.1100) antibody
  • chromosome region maintenance protein 1 (xpo1) antibody
  • exportin 1 (Xpo1) antibody
  • exportin 1 (CRM1 homolog, yeast) (XPO1) antibody
  • exportin 1 (CRM1 homolog, yeast) (LOC100220104) antibody
  • exportin 1 (CRM1 homolog) (xpo1) antibody
  • exportin 1, CRM1 homolog (yeast) (Xpo1) antibody
  • 18.m06600 antibody
  • AA420417 antibody
  • CG13387 antibody
  • crm1 antibody
  • dCRM1 antibody
  • DDBDRAFT_0183812 antibody
  • DDBDRAFT_0234066 antibody
  • DDB_0183812 antibody
  • DDB_0234066 antibody
  • Dmel\\CG13387 antibody
  • emb antibody
  • Exp1 antibody
  • exportin-1 antibody
  • l(2)k16715 antibody
  • LOC100220104 antibody
  • Xpo antibody
  • XPO-1 antibody
  • Xpo1 antibody

Protein level used designations for XPO1

CG13387-PA , Exportin-1 , chromosomal region maintenance 1 , emb-PA , exportin , exportin 1 , exportin-1 , exportin 1 (CRM1 homolog, yeast) , exportin 1-like , exportin-1-like , CRM1, yeast, homolog , chromosome region maintenance 1 protein homolog , exportin 1 (CRM1, yeast, homolog) , exportin-1 (required for chromosome region maintenance) , nuclear export factor CRM1 , CRM1/XPO1 protein , exp1

34167 Drosophila melanogaster
3374090 Cryptosporidium parvum Iowa II
3551041 Trypanosoma cruzi strain CL Brener
3665310 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5478474 Babesia bovis T2Bo
5656223 Leishmania major strain Friedlin
8628079 Dictyostelium discoideum AX4
100313952 Solanum lycopersicum
718063 Macaca mulatta
100165622 Acyrthosiphon pisum
100220104 Taeniopygia guttata
100343451 Oryctolagus cuniculus
100378670 Saccoglossus kowalevskii
100410392 Callithrix jacchus
100605083 Nomascus leucogenys
100633509 Amphimedon queenslandica
7514 Homo sapiens
510568 Bos taurus
474609 Canis lupus familiaris
459534 Pan troglodytes
397330 Sus scrofa
399087 Xenopus laevis
103573 Mus musculus
85252 Rattus norvegicus
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