Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human DBN1 Antibodies:
anti-Mouse (Murine) DBN1 Antibodies:
anti-Rat (Rattus) DBN1 Antibodies:
Go to our pre-filtered search.
Cow (Bovine) Monoclonal DBN1 Primary Antibody for ICC, IF - ABIN151450
Kojima, Kato, Shirao, Obata: Nucleotide sequences of two embryonic drebrins, developmentally regulated brain proteins, and developmental change in their mRNAs. in Brain research 1989
Show all 6 Pubmed References
Human Monoclonal DBN1 Primary Antibody for FACS, WB - ABIN1558085
Hayashi, Ishikawa, Kawai-Hirai, Takagi, Taketomi, Shirao: Domain analysis of the actin-binding and actin-remodeling activities of drebrin. in Experimental cell research 2000
Show all 5 Pubmed References
Human Polyclonal DBN1 Primary Antibody for IHC (fro), IF - ABIN285747
Ganong, Kramer, Salmon, Reid, Lovinger, Scapagnini, Boryczka, Shackelford: Pharmacological evidence for inhibition of ACTH secretion by a central adrenergic system in the dog. in Neuroscience 2001
Drebrin reduces SMC (show DYM Antibodies) activation through its interaction with the actin cytoskeleton but independently of its interaction with Homer (show HOMER1 Antibodies) scaffolds to prevent neointima formation.
Exploring the relationship between drebrin and cognitive function may provide insight into the early prevention of cognitive impairment and in the diagnosis and treatment of Alzheimer's disease.
Drebrin is critical for progranulin (show GRN Antibodies)-dependent activation of the Akt (show AKT1 Antibodies) and MAPK (show MAPK1 Antibodies) pathways and modulates motility, invasion and anchorage-independent growth in bladder neoplasms.
The study compared the proteome profiles of the human colon adenocarcinoma cell line HCT-116 with its metastatic derivative E1. DBN1 was found to be overexpressed in E1 as compared to HCT-116 cells.
In basal cell carcinoma tissues, intense and homogeneous drebrin expression was observed mainly at tumor cell-cell boundaries. In contrast, drebrin was stained only weakly and non-homogeneously in trichoblastoma and trichoepthelioma tissue samples.
Rab8a (show RAB8A Antibodies) and Drebrin E act as key proteins in the regulation of apical trafficking in intestinal epithelial cells.
drebrin has a role in HIV infection by modulating viral entry, mainly through the control of actin cytoskeleton polymerization in response to HIV-1
These findings show that drebrin contains a cryptic F-actin-bundling activity regulated by phosphorylation and provide a mechanistic model for microtubule-F-actin coupling.
decreasing the drebrin E levels disrupted the normal subapical F-actin-myosin-IIB (show MYH10 Antibodies)-betaII-spectrin network and the apical accumulation of EB3 (show MAPRE3 Antibodies), a microtubule-plus-end-binding protein
Drebrin contributes to the maintenance of cell shape, and may play an important role in glioma cell motility.
Study determines the specific roles of drebrin in the regulation of the axonal cytoskeleton, and provides evidence that drebrin contributes to the coordination of the actin and microtubule cytoskeleton during the initial stages of axon branching.
Data suggest further studies to elucidate the effect of drebrin (Dbn) on the development and progression of Alzheimer's disease (AD).
Study demonstrated that isoform conversion of drebrin is critical, and that drebrin A is indispensable for adult hippocampal synaptic plasticity and hippocampus-dependent fear learning; the phenotype of drebrin A knockout mice suggests functional differences between drebrin A and drebrin E
These findings provide unprecedented experimental support for a role of drebrin in the regulation of memory-related synaptic plasticity and neurotransmitter receptor (show GRIN1 Antibodies) signaling
Dbn1 regulates systemic anaphylaxis and IgE/Fcgr1-induced degranulation in mast cells by regulating actin reorganization and actin dynamics.
SAHA likely inhibits ADDL (show ADD3 Antibodies)-induced drebrin loss from dendritic spines by stabilizing drebrin in these structures, rather than by increasing drebrin clusters or dendritic protrusions
These results suggest that Cdk5 (show CDK5 Antibodies)-p35 (show CDK5R1 Antibodies) regulates neuronal migration through phosphorylation of drebrin in growth cone processes.
Double knockout Psen1Psen2 leads to a decrease in immunoreactivity for drebrin A at both synaptic and nonsynaptic areas of CA1 (show CA1 Antibodies) hippocampus.
The density of drebrin-positive glutamatergic synapses formed on GABAergic neurons is lower than those on glutamatergic neurons.
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
, developmentally-regulated brain protein
, drebrin E
, drebrin E2
, drebrin A
, developmentally regulated brain protein