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Browse our C-JUN Proteins (JUN)

Full name:
Jun Proto-Oncogene Proteins (JUN)
On are 24 Jun Proto-Oncogene (JUN) Proteins from 11 different suppliers available. Additionally we are shipping C-JUN Antibodies (772) and C-JUN Kits (72) and many more products for this protein. A total of 929 C-JUN products are currently listed.
AP-1, AP1, B230310J22Rik, Bsk, BSK/DJNK, c-jun, CG2275, CG5680, cJun, D-JNK, d-JRA, d-jun, D-jun/Jra, D-junk, dAP-1, DBSK/JNK, dJNK, DJNK/bsk, dJra, djun, dm-Jun, Dmel\\CG2275, Dmel\\CG5680, fj36h07, jnk, JNK/SAPK, jra, jun, Junc, Junk, l(2)46Ef, l(2)IA109, l(2R)IA109, p39, SAPKa, V, wu:fj36h07, zgc:65863
list all proteins Gene Name GeneID UniProt
JUN 12570 O35926
JUN 3725 P05412
JUN 24516 P17325

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C-JUN Proteins (JUN) by Origin

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Top referenced C-JUN Proteins

  1. Human C-JUN Protein expressed in Escherichia coli (E. coli) - ABIN667382 : Bannister, Gottlieb, Kouzarides, Jackson: c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif. in Nucleic acids research 1993 (PubMed)
    Show all 2 references for ABIN667382

  2. Human C-JUN Protein expressed in Escherichia coli (E. coli) - ABIN411906 : Michaelis, Ansar, Chen, Reiff, Seyb, Himes, Audus, Georg: {beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents. in The Journal of pharmacology and experimental therapeutics 2005 (PubMed)

More Proteins for C-JUN Interaction Partners

Xenopus laevis Jun Proto-Oncogene (JUN) interaction partners

  1. AP-1(c-Jun/FosB (show FOSB Proteins)) may play a role in neurogenesis via the induction of FoxD5b expression during early vertebrate development

  2. The cJun transcription factor bound to a variant cAMP response element in the promoter region of tlx3 (show TLX3 Proteins) and modulated transcription and regulated neurotransmitter phenotype via its transactivation domain

Fruit Fly (Drosophila melanogaster) Jun Proto-Oncogene (JUN) interaction partners

  1. malignant transformation of the ras(V12)scrib(1) tumors requires bZIP protein Fos, the ETS (show ETS1 Proteins)-domain factor Ets21c and the nuclear receptor Ftz-F1 (show NR5A2 Proteins), all acting downstream of Jun-N-terminal kinase (show MAPK8 Proteins).

  2. Diminished MTORC1-dependent JNK (show MAPK8 Proteins) activation underlies the neurodevelopmental defects associated with lysosomal dysfunction.

  3. ROS (show ROS1 Proteins)/JNK (show MAPK8 Proteins)/p38 (show MAPK14 Proteins)/Upd (show UROD Proteins) stress responsive module restores tissue homeostasis. This module is not only activated after cell death induction but also after physical damage and reveals one of the earliest responses for imaginal disc regeneration.

  4. Significantly, the JNK (show MAPK8 Proteins) pathway is responsible for the majority of the phenotypes and transcriptional changes downstream of Notch (show NOTCH1 Proteins)-Src (show SRC Proteins) synergy.

  5. This study demonstrated that the mechanism by which Bsk (show FRK Proteins) is required for pruning is through reducing the membrane levels of the adhesion molecule (show NCAM1 Proteins) Fasciclin II (show NCAM2 Proteins) (FasII)

  6. Jra recruits the HP1a (show CBX5 Proteins)/KDM4A (show KDM4A Proteins) complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation

  7. Study solves the crystal structure of unphosphorylated DJNK in complex with adenylyl imidodiphosphate (AMP (show AMPH Proteins)-PNP (show NP Proteins)) and magnesium.

  8. PERK/ATF4 activated the JNK pathway through Rac1 and Slpr activation in apoptotic cells.

  9. Data show that oxidative stress and neuroinflammation are intrinsic components of TDP-43 (show TARDBP Proteins)-associated neurodegeneration and the balance between cytoprotective JNK (show MAPK8 Proteins) and cytotoxic p38 (show MAPK14 Proteins) signaling dictates phenotypic outcome to TDP-43 (show TARDBP Proteins) expression in Drosophila.

  10. Data show that the actin-Capping Protein (show TMOD4 Proteins) (CP) alphabeta heterodimer, which regulates actin (show ACTB Proteins) filament (F-actin (show ACTB Proteins)) polymerization, limits Src (show SRC Proteins)-induced apoptosis or tissue overgrowth by restricting JNK (show MAPK8 Proteins) activation.

Pig (Porcine) Jun Proto-Oncogene (JUN) interaction partners

  1. The effects of prostaglandin F2alpha administration on transcription factor AP-1 expression and the expression of downstream genes involved in luteolysis are reported.

Rabbit Jun Proto-Oncogene (JUN) interaction partners

  1. ICAM1 (show ICAM1 Proteins) and IL10 (show IL10 Proteins) were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 may be responsible for this upregulation.

Mouse (Murine) Jun Proto-Oncogene (JUN) interaction partners

  1. In a model of heavy metal poisoning, copper contamination of drinking water (as can occur with corrosion in aging plumbing systems) up-regulates binding of transcription factor AP-1 in neurons of brain, even in low concentrations.

  2. Transplant-induced reactivation of murine cytomegalovirus immediate early gene expression is associated with recruitment of NF-kappaB (show NFKB1 Proteins) and AP-1 to the major immediate early promoter.

  3. These data suggest p35 (show CDK5R1 Proteins) and p39 (show ATP6V0D1 Proteins) have specific and overlapping roles in oligodendrocyte development, some of which may be independent of Cdk5 (show CDK5 Proteins) activation.

  4. ERK (show EPHB2 Proteins) contributes to the morphine-induced hyperalgesia by regulating the activation of c-JUN

  5. These results indicate that both NF-kappaB (show NFKB1 Proteins) and c-Jun/AP-1 are involved in regulating anti-beta2GPI-induced expression of prothrombotic and proinflammatory molecules in vivo.

  6. Tumorigenesis by Meis1 (show MEIS1 Proteins) overexpression is accompanied by a change of DNA target-sequence specificity which allows binding to the AP-1 element.

  7. BMP7 (show BMP7 Proteins) and FGF9 coordinately regulate AP-1 transcription to promote G1-S cell cycle progression and nephron progenitor cells proliferation.

  8. Our findings conclude that pharmacological actions of CoQ0 are mediated via inhibition of NFkappaB/AP-1 activation and induction of Nrf2 (show NFE2L2 Proteins)/ARE-signaling.

  9. Taken together, our results suggest that LPS (show TLR4 Proteins) induces PDK4 (show PDK4 Proteins) expression and alters glucose metabolism via the JNK (show MAPK8 Proteins) pathway.

  10. In the heterologous mouse model loss of c-Jun expression led to ablation of dissemination of Theileria annulata-infected and transformed macrophages.

Human Jun Proto-Oncogene (JUN) interaction partners

  1. The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis.

  2. Findings indicate a role for transcription factor c-Jun as a driver of cancer cell metabolic reprogramming, and suggest that cancers overexpressing JUN may be especially sensitive to glutaminase (GLS (show GLS Proteins))-targeted therapies.

  3. JNK/c-Jun activation and BIM (show BCL2L11 Proteins) induction is a late pro-apoptotic response of glioma cells treated with alkylating anticancer drugs.

  4. A novel AP-1 (show FOSB Proteins) binding site at -1363 bp of the human TF promoter region was identified.

  5. amplification of HMGA2 was associated with the atypical lipomatous tumor/well-differentiated liposarcoma histological type and a good prognosis, whereas CDK4 (show CDK4 Proteins) and JUN amplifications were associated with dedifferentiated liposarcoma histology

  6. CARMA1 (show CARD11 Proteins)- and MyD88 (show MYD88 Proteins)-dependent activation of Jun/ATF-type AP-1 (show FOSB Proteins) complexes is a hallmark of ABC (show ABCB6 Proteins) diffuse large B-cell lymphomas.

  7. NCOA1 (show NCOA1 Proteins) potentiates breast cancer angiogenesis through upregulating HIF1alpha (show HIF1A Proteins) and AP-1 (show FOSB Proteins)-mediated VEGFa (show VEGFA Proteins) expression

  8. mitochondrial dysfunction induces EMT (show ITK Proteins) through TGF-beta (show TGFB1 Proteins)/Smad (show SMAD1 Proteins)/Snail (show SNAI1 Proteins) signaling via c-Jun/AP-1 activation.

  9. cistrome for the AP-1 (show FOSB Proteins) transcription factor c-Jun is comprised of 13,800 binding regions in TNFalpha (show TNF Proteins)-stimulated triple-negative breast cancer cells.

  10. Simultaneous high expression of ID1 and c-Jun or c-Fos was correlated with poor survival in esophageal squamous cell carcinoma patients.

Zebrafish Jun Proto-Oncogene (JUN) interaction partners

  1. CPEB-1 (show CPEB1 Proteins) control of c-Jun mRNA translation regulates GH gene expression and resulting downstream signaling events (e.g., synaptic plasticity) in the mouse hippocampus.

Cow (Bovine) Jun Proto-Oncogene (JUN) interaction partners

  1. The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 DNA-binding activity and expression of several transcriptions factors in breast cancer cells.

  2. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Proteins) synthesis in the presence of IL-1beta (show IL1B Proteins) and/or inhibitors of the MAPKs and NFkappaB and AP-1 signalling pathways

C-JUN (JUN) Protein Profile

Protein Summary

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Alternative names and synonyms associated with C-JUN (JUN)

  • jun oncogene (jun)
  • basket (bsk)
  • C-JUN protein (C-JUN)
  • c-Jun protein (C-JUN)
  • c-jun transcription factor (C-JUN)
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (Cdk5r2)
  • Jun oncogene (Jun)
  • jun proto-oncogene (JUN)
  • jun proto-oncogene (jun)
  • jun proto-oncogene (Jun)
  • Jun-related antigen (Jra)
  • AP-1 protein
  • AP1 protein
  • B230310J22Rik protein
  • Bsk protein
  • BSK/DJNK protein
  • c-jun protein
  • CG2275 protein
  • CG5680 protein
  • cJun protein
  • D-JNK protein
  • d-JRA protein
  • d-jun protein
  • D-jun/Jra protein
  • D-junk protein
  • dAP-1 protein
  • DBSK/JNK protein
  • dJNK protein
  • DJNK/bsk protein
  • dJra protein
  • djun protein
  • dm-Jun protein
  • Dmel\\CG2275 protein
  • Dmel\\CG5680 protein
  • fj36h07 protein
  • jnk protein
  • JNK/SAPK protein
  • jra protein
  • jun protein
  • Junc protein
  • Junk protein
  • l(2)46Ef protein
  • l(2)IA109 protein
  • l(2R)IA109 protein
  • p39 protein
  • SAPKa protein
  • V protein
  • wu:fj36h07 protein
  • zgc:65863 protein

Protein level used designations for Jun Proto-Oncogene Proteins (JUN)

v-jun sarcoma virus 17 oncogene homolog , CG5680-PB , CG5680-PE , CG5680-PF , JNK , JUN kinase , Jun N-terminal kinase , Jun NH2-terminal kinase , Jun-N-terminal kinase , Jun-kinase , bsk-PB , bsk-PE , bsk-PF , c-Jun N-terminal kinase , c-Jun aminoterminal kinase , c-Jun-N-terminal kinase , drosophila JNK , AP1 , V-jun avian sarcoma virus 17 oncogene homolog , activator protein 1 , proto-oncogene c-jun , transcription factor AP-1 , CDK5 activator 2 , cyclin-dependent kinase 5 activator 2 , cyclin-dependent kinase 5 regulatory subunit 2 , p39I , AH119 , immediate early , jun A , Jun activation domain binding protein , enhancer-binding protein AP1 , jun oncogene , p39 , proto-oncogene c-Jun , v-jun avian sarcoma virus 17 oncogene homolog , Avian sarcoma virus 17 (v-jun) oncogene homolog , Jun oncogene , v-jun sarcoma virus 17 oncogene , CG2275-PA , CG2275-PB , CG2275-PC , Jra-PA , Jra-PB , Jra-PC , Jun related antigen , complementation group V , lethal(2)1A109 , lethal(2)IA109

379050 Xenopus laevis
44801 Drosophila melanogaster
396913 Sus scrofa
443219 Ovis aries
100008856 Oryctolagus cuniculus
12570 Mus musculus
16476 Mus musculus
3725 Homo sapiens
335916 Danio rerio
24516 Rattus norvegicus
399400 Xenopus laevis
424673 Gallus gallus
609429 Canis lupus familiaris
280831 Bos taurus
100170668 Ovis aries
36057 Drosophila melanogaster
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