Browse our Calnexin Proteins (CANX)

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Calnexin Proteins (CANX)
On are 22 Calnexin (CANX) Proteins from 10 different suppliers available. Additionally we are shipping Calnexin Antibodies (387) and Calnexin Kits (40) and many more products for this protein. A total of 460 Calnexin products are currently listed.
1110069N15Rik, AI988026, canx, CG11958, clgn, clnx, Cnx, D11Ertd153e, Dmel\CG11958, IP90, P90, PP90, wu:fe06b12, zgc:63524
list all proteins Gene Name GeneID UniProt
CANX 821 P27824
CANX 12330 P35564
CANX 29144 P35565

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Calnexin Proteins (CANX) by Origin

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Top referenced Calnexin Proteins

  1. Human Calnexin Protein expressed in Escherichia coli (E. coli) - ABIN666892 : Millar, Whitelegge, Bindschedler, Rayon, Boudet, Rossignol, Borderies, Bolwell: The cell wall and secretory proteome of a tobacco cell line synthesising secondary wall. in Proteomics 2009 (PubMed)
    Show all 2 references for 666892

More Proteins for Calnexin Interaction Partners

Zebrafish Calnexin (CANX) interaction partners

  1. Results suggest that calnexin is essential for neuromast formation during lateral line development.

Human Calnexin (CANX) interaction partners

  1. FUNDC1 (show FUNDC1 Proteins) integrates mitochondrial fission and mitophagy at the interface of the endoplasmic reticulum-mitochondrial contact site by working in concert with DRP1 (show CRMP1 Proteins) and calnexin under hypoxic conditions in mammalian cells.

  2. Results of further analyses by using a CNX mutant imply that ERp29 (show ERP29 Proteins) and ERp57 (show PDIA3 Proteins) recognize the same domain of CNX, whereas the mode of interaction with CNX might be somewhat different between them.

  3. Inhibit interaction between HIV-1 Nef and Calnexin to reverse HIV-induced lipid accumulation and prevent atherosclerosis.

  4. Endogenous NOX4 (show NOX4 Proteins) forms macromolecular complexes with calnexin, which are needed for the proper maturation, processing, and function of NOX4 (show NOX4 Proteins) in the endoplasmic reticulum.

  5. To study principles underlying dynamics and regulation of palmitoylation, the ER chaperone calnexin, which requires dual palmitoylation for function, was investigated.

  6. These observations point at a previously unrecognized contribution of calnexin to the retention of NMT1 (show NMT1 Proteins) at the ER membrane.

  7. Charcot-Marie-Tooth disease-related PMP22 (show PMP22 Proteins) is trapped in the endoplasmic reticulum by calnexin-dependent retention and Rer1 (show RER1 Proteins)-mediated early Golgi retrieval systems and partly degraded by the Hrd1 (show SYVN1 Proteins)-mediated endoplasmic reticulum-associated degradation system.

  8. Data indicate that protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Proteins)) association with calnexin is ubiquitin conjugating enzyme 9 (UBC9 (show UBE2I Proteins))-dependent.

  9. H-ERG (show KCNH2 Proteins) trafficking was impaired by H2O2 after 48 h treatment, accompanied by reciprocal changes of expression between miR-17-5p seed miRNAs and several chaperones (Hsp70 (show HSP70 Proteins), Hsc70 (show HSPA8 Proteins), CANX, and Golga20)

  10. Nef regulates the activity of calnexin to stimulate its interaction with gp160 (show ENPEP Proteins) at the expense of ABCA1 (show ABCA1 Proteins)

Mouse (Murine) Calnexin (CANX) interaction partners

  1. CNX has a specific role in cardiomyocyte viability and Ca(2 (show CA2 Proteins)+) cycling through its effects on endoplasmic reticulum stress, apoptosis and Ca(2 (show CA2 Proteins)+) channel expression.

  2. Calnexin discriminates between different conformational states of GlyT2 displaying a lectin-independent chaperone activity.

  3. calnexin and ERp57 (show PDIA3 Proteins), but not calreticulin (show CALR Proteins), play an important role in the biology of peripheral myelin proteins PMP22 (show PMP22 Proteins) and P0, and, consequently, these chaperones may contribute to the pathogenesis of peripheral neuropathies

  4. Enhanced clathrin-dependent endocytosis in the absence of calnexin may contribute to the neurological phenotype of calnexin-deficient mice

  5. Data show that the E351 mutation led to slightly enhanced ERp57 (show PDIA3 Proteins) binding to calnexin, whereas W428 greatly enhanced binding of ERp57 (show PDIA3 Proteins) to calnexin.

  6. Suggest that Adam7 (show ADAM7 Proteins) functions in fertilization through the formation of a complex with heat shock protein 5 (show HSPA5 Proteins), calnexin and Itm2b (show ITM2B Proteins) during capacitation in sperm.

  7. endoplasmic reticulum stress has effects on group VIA phospholipase A2 (show YWHAZ Proteins) in beta cells that include tyrosine phosphorylation and increased association with calnexin

  8. Calnexin deficiency leads to dysmyelination

  9. Data give novel evidence that CyCAP (show LGALS3BP Proteins) regulates the post-translational modification of tissue transglutaminase (show TGM2 Proteins) through its colocalization with calnexin in endoplasmic reticulum.

  10. Association with mutant peripheral myelin protein-22 (show PMP22 Proteins) ex vivo: a basis for "gain-of-function" ER diseases.

Calnexin (CANX) Protein Profile

Protein Summary

This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

Alternative names and synonyms associated with Calnexin (CANX)

  • calnexin (canx)
  • calnexin (CANX)
  • calnexin (CNX)
  • calnexin (LOC100283947)
  • calnexin (LOC100304606)
  • calnexin (canx-a)
  • calnexin (Canx)
  • Calnexin 99A (Cnx99A)
  • 1110069N15Rik protein
  • AI988026 protein
  • canx protein
  • CG11958 protein
  • clgn protein
  • clnx protein
  • Cnx protein
  • D11Ertd153e protein
  • Dmel\CG11958 protein
  • IP90 protein
  • P90 protein
  • PP90 protein
  • wu:fe06b12 protein
  • zgc:63524 protein

Protein level used designations for Calnexin Proteins (CANX)

calmegin , calnexin , GRMZM2G134668 , hypothetical protein , major histocompatibility complex class I antigen-binding protein p88 , CG11958-PA , CG11958-PB , CG11958-PD , CG11958-PE , Cnx99A-PA , Cnx99A-PB , Cnx99A-PD , Cnx99A-PE , calnexin 99A , calnexin99A

406757 Danio rerio
448161 Xenopus (Silurana) tropicalis
462330 Pan troglodytes
542421 Zea mays
704794 Macaca mulatta
100283947 Zea mays
100304606 Ictalurus punctatus
821 Homo sapiens
407129 Bos taurus
380018 Xenopus laevis
416288 Gallus gallus
100519184 Sus scrofa
101122273 Ovis aries
100341645 Oryctolagus cuniculus
12330 Mus musculus
29144 Rattus norvegicus
100726237 Cavia porcellus
403908 Canis lupus familiaris
100174065 Pongo abelii
101085686 Felis catus
44643 Drosophila melanogaster
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