Browse our Caspase 9 Proteins (CASP9)

Full name:
Caspase 9, Apoptosis-Related Cysteine Peptidase Proteins (CASP9)
On are 20 Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) Proteins from 7 different suppliers available. Additionally we are shipping Caspase 9 Antibodies (468) and Caspase 9 Kits (75) and many more products for this protein. A total of 584 Caspase 9 products are currently listed.
AI115399, APAF-3, APAF3, AW493809, CASP-9, Casp-9-CTD, CASP9, Casp9_v1, Caspase-9, Ice-Lap6, MCH6, PPP1R56
list all proteins Gene Name GeneID UniProt
CASP9 12371  
CASP9 58918  
CASP9 842 P55211

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Caspase 9 Proteins (CASP9) by Origin

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Top referenced Caspase 9 Proteins

  1. Human Caspase 9 Protein expressed in Escherichia coli (E. coli) - ABIN2487277 : Azuma, Koths, Flanagan, Kwiatkowski: Gelsolin in complex with phosphatidylinositol 4,5-bisphosphate inhibits caspase-3 and -9 to retard apoptotic progression. in The Journal of biological chemistry 2000 (PubMed)
    Show all 8 references for 2487277

More Proteins for Caspase 9 Interaction Partners

Mouse (Murine) Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) interaction partners

  1. inducible caspase-9 (iC9) safety switch can eliminate CD19 (show CD19 Proteins).CAR-Ts in a dose-dependent manner, allowing either a selective containment of CD19 (show CD19 Proteins).CAR-T expansion in case of CRS (show CARS Proteins) or complete deletion on demand granting normal B cell reconstitution.

  2. Cepharanthine treatment reduced mitochondrial membrane potential and upregulated the level of cleaved caspases, including caspase-9 and caspase-3 (show CASP3 Proteins)/7, in a dose-dependent fashion.

  3. Bcl-2 (show BCL2 Proteins)-caspase-9 apoptosis pathway was clearly activated in the testis of asthmatic mice with the increased expression of apoptosis-related proteins.

  4. Inhibition of Caspase-9 restricted, while Apaf-1 promoted, Chlamydia pneumoniae infection in HEp-2, HeLa, and mouse epithelial fibroblast (MEF) cells.

  5. The study demonstrates sublethal caspase (show CASP3 Proteins)-activation has an important role in cardiomyocyte differentiation and may have significant implications for promoting cardiac regeneration after myocardial injury involving exogenous or endogenous cell sources.

  6. Casp6 (show CASP6 Proteins) knockout in YAC128 mice does not abolish the presence of the mutant HTT (show HTT Proteins) protein-586 fragment but ameliorates depression, body weight gain, IGF-1 (show IGF1 Proteins) and BDNF (show BDNF Proteins) levels in YAC128 mice.

  7. study demonstrates that MMP-3 (show MMP3 Proteins) leads to caspase-9 activation and suggests that this occurs indirectly via a cytosolic protein, possibly involving Apaf-1 (show APAF1 Proteins)

  8. caspase-9 mediates Puma (show BBC3 Proteins) activation to determine the threshold for overcoming chemoresistance in cancer cells.

  9. Casp9, the initiator caspase (show CASP3 Proteins) of the intrinsic apoptotic cascade, has a role in murine fetal and adult hematopoiesis

  10. findings demonstrate that focal activation of caspase-9 and -3 at neuromuscular junctions is essentially responsible for subsynaptic DNA damage and apoptotic synaptic degeneration in slow-channel myasthenic syndrome

Human Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) interaction partners

  1. Fisetin inhibited Triple-Negative Breast Cancer Cells cell division and induced apoptosis, which was associated with mitochondrial membrane permeabilization and the activation of caspase-9 and caspase-8 (show CASP8 Proteins), as well as the cleavage of poly(ADP-ribose) polymerase-1 (show PARP1 Proteins).

  2. High CASP9 expression is associated with Lung Tumorigenesis.

  3. caspase-8 (show CASP8 Proteins) and caspase-9 contribute to the cyclic stretch-induced apoptosis, but functioned differently at different stages in human periodontal ligament cells

  4. knockdown of HMGI-C led to the significant induction of apoptosis via mitochondrial pathway by inducing miR34a and cell cycle arrest in MDA-MB-468 cells in vitro.

  5. Results suggest that the formation of the apoptosome accompanied by the activation of caspase-9 may occur in brains affected by multiple system atrophy (MSA (show TPO Proteins)), and that a mitochondria-dependent apoptotic pathway may be partially associated with the pathogenesis of MSA (show TPO Proteins).

  6. Using recombinant proteins, this study investigated the influence of survivin (show BIRC5 Proteins) on the inhibition of caspase-9 by XIAP (show XIAP Proteins) in vitro. With a fluorescence-based assay for the apoptosome-stimulated activity of caspase-9, the study shows that survivin (show BIRC5 Proteins) has no effect on the inhibition of caspase-9 by XIAP (show XIAP Proteins), neither in the presence nor in the absence of Smac (show DIABLO Proteins).

  7. LRRC8A (show LRRC8A Proteins) is an essential regulator of cisplatin induced p53 (show TP53 Proteins) protein activity and its downstream signaling involving increased expression of p21Waf1/Cip1 and MDM2 (show MDM2 Proteins), as well as activation of caspase-9 and -3 in tumor cell lines.

  8. Data show that caspase 9 (CASP9) single nucleotide polymorphism (rs1052576) TT genotype was seemed to be associated with higher risk of pathological stage.

  9. Data show that the apoptotic and cytotoxic effects of BL-038 are mediated by the intrinsic mitochondria-mediated apoptotic pathway, which in turn causes the activation of caspase-9 and caspase-3 (show CASP3 Proteins), and the cleavage of poly (ADP-ribose) polymerase (PARP (show PARP1 Proteins)), to elicit apoptosis response.

  10. Downregulation of DNMT3a (show DNMT3A Proteins) regulated miR (show MLXIP Proteins)-182 via caspase-3 (show CASP3 Proteins) and -9-mediated apoptosis and DNA damage response in ovarian cancer.

Cow (Bovine) Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) interaction partners

  1. Suppression of caspase-9 resulted in significant upregulation of cell proliferation-, adhesion-, growth-, development- and division-regulating genes, and the downregulation of cell death program- and stress response-regulating genes.

  2. Endothelial cell apoptosis by H. somnus-activated platelets required activation of both caspase-8 (show CASP8 Proteins) and caspase-9.

Pig (Porcine) Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) interaction partners

  1. The ATP and cytochrome c (show CYCS Proteins) dependent activation of caspase-9 is increased during hypoxia. The ATP and cytochrome c (show CYCS Proteins) sites of Apaf-1 (show APAF1 Proteins) that mediate caspase-9 activation are modified during hypoxia.

  2. Results suggest that zearalenone induces apoptosis and necrosis of porcine granulosa cells in a dose-dependent manner via a caspase-3 (show CASP3 Proteins)- and caspase-9-dependent mitochondrial pathway.

  3. We conclude that the hypoxia-induced activation of caspase-9 is mediated by Src kinase (show CSK Proteins).

Caspase 9 (CASP9) Protein Profile

Protein Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1\; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

Alternative names and synonyms associated with Caspase 9 (CASP9)

  • caspase 9 (CASP9)
  • caspase 9 (LOC100101592)
  • caspase 9 (Casp9)
  • caspase 9, apoptosis-related cysteine peptidase (Casp9)
  • caspase 9, apoptosis-related cysteine peptidase (CASP9)
  • caspase-9-like (LOC100518913)
  • AI115399 protein
  • APAF-3 protein
  • APAF3 protein
  • AW493809 protein
  • CASP-9 protein
  • Casp-9-CTD protein
  • CASP9 protein
  • Casp9_v1 protein
  • Caspase-9 protein
  • Ice-Lap6 protein
  • MCH6 protein
  • PPP1R56 protein

Protein level used designations for CASP9

caspase 9 , ICE-like apoptotic protease 6 , apoptotic protease Mch-6 , apoptotic protease-activating factor 3 , caspase-9 , 25 kDa caspase-9 dominant negative protein , Ice-like apoptotic protease 6 , apoptotic protease activating factor 3 , caspase-9 dominant negative form , caspase-9-carboxyl-terminal divergent , apoptotic protease MCH-6 , protein phosphatase 1, regulatory subunit 56 , caspase 9, apoptosis-related cysteine protease

768260 Felis catus
100101592 Oryctolagus cuniculus
12371 Mus musculus
58918 Rattus norvegicus
842 Homo sapiens
487432 Canis lupus familiaris
100140945 Bos taurus
101110953 Ovis aries
100714954 Cavia porcellus
100518913 Sus scrofa
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