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Browse our Cortactin Proteins (CTTN)

Full name:
Cortactin Proteins (CTTN)
On www.antibodies-online.com are 8 Cortactin (CTTN) Proteins from 4 different suppliers available. Additionally we are shipping Cortactin Antibodies (212) and Cortactin Kits (8) and many more products for this protein. A total of 245 Cortactin products are currently listed.
Synonyms:
1110020L01Rik, CG3637, cortactin, cttn, CTTN1, Cttnb, Dmel\CG3637, EMS1, P85.25
list all proteins Gene Name GeneID UniProt
CTTN 13043 Q60598
CTTN 2017 Q14247
CTTN 60465  

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Cortactin Proteins (CTTN) by Origin

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Top referenced Cortactin Proteins

  1. Human Cortactin Protein expressed in HEK-293 Cells - ABIN2712518 : Labrador-Horrillo, Martínez, Selva-OCallaghan, Trallero-Araguás, Grau-Junyent, Vilardell-Tarrés, Juarez: Identification of a novel myositis-associated antibody directed against cortactin. in Autoimmunity reviews 2014 (PubMed)
    Show all 3 references for ABIN2712518

More Proteins for Cortactin Interaction Partners

Mouse (Murine) Cortactin (CTTN) interaction partners

  1. AMPK (show PRKAA1 Proteins) phosphorylation of cortactin followed by SIRT1 (show SIRT1 Proteins) deacetylation modulates the interaction of cortactin and cortical-actin in response to shear stress. Functionally, this AMPK (show PRKAA1 Proteins)/SIRT1 (show SIRT1 Proteins) coregulated cortactin-F-actin dynamics is required for endothelial nitric oxide synthase (show NOS3 Proteins) subcellular translocation/activation and is atheroprotective.

  2. Cortactin may have an important role in the development of oral tumors in mice

  3. findings reveal that Keap1 (show KEAP1 Proteins) regulates cell migration by affecting the subcellular localization and activity of cortactin independently of its role in oxidant stress responses.

  4. association of cortactin with Pfn-1 (show PFN1 Proteins) is regulated by c-Abl (show ABL1 Proteins)-mediated cortactin phosphorylation

  5. Cell proliferation, migration and invasion were inhibited by genetic knockdown of EMS1.

  6. our findings suggest that after GnRHa activation, src activity leads to tyrosine phosphorylation of cortactin, which facilitates its association with Arp3 to engage the actin cytoskeleton.

  7. GIT1-cortactin association through GIT1-Spa (show FASL Proteins) homology domain is required for cortactin localization to the leading edge and is essential for endothelial cell directional migration and tumor angiogenesis.

  8. Data indicate that cortactin as an Src (show SRC Proteins)-dependent interacting partner of EB1 (show MAPRE1 Proteins).

  9. Introduction of three 4-R-hydroxyproline residues stabilizes the SH3m-cortactin binding of HPK1 (show MAP4K1 Proteins) peptide.

  10. mXinalpha together with cortactin is able to modulate the p120-catenin (show CTNND1 Proteins) activity for shape change and adhesion at the intercalated discs.

Cow (Bovine) Cortactin (CTTN) interaction partners

  1. These findings suggest that this common cortactin variant may functionally contribute to ALI predisposition by impeding endothelial wound healing.

Human Cortactin (CTTN) interaction partners

  1. Unique role for PBF (show PTTG1IP Proteins) in regulating CTTN function to promote endocrine cell invasion and migration.

  2. AMPK (show PRKAA1 Proteins) phosphorylation of cortactin followed by SIRT1 (show SIRT1 Proteins) deacetylation modulates the interaction of cortactin and cortical-actin in response to shear stress. Functionally, this AMPK (show PRKAA1 Proteins)/SIRT1 (show SIRT1 Proteins) coregulated cortactin-F-actin dynamics is required for endothelial nitric oxide synthase (show NOS3 Proteins) subcellular translocation/activation and is atheroprotective.

  3. These data suggest a model in which cortactin promotes exosome secretion by stabilizing cortical actin-rich multivesicular late endosome docking sites.

  4. Cortactin may have an important role in the development of oral tumors in human

  5. a dynamic TIP150 (show KIAA0774 Proteins)-cortactin interaction orchestrates directional cell migration via coupling dynamic microtubule plus ends to the cortical cytoskeleton.

  6. Study showed that dynamin 2 and cortactin participate in the formation of F-actin bundles, which stabilize filopodia in migrating cancer cells.

  7. Amplification of 11q13 resulting in overexpression of CTTN/CCND1 (show CCND1 Proteins) was the most prominent finding, which was observed in 13 of 19 ESCC cases.

  8. The cortactin Tyr421 residue is required to promote cell proliferation both in vitro and in vivo.

  9. the expression of CTTN, Exo70 (show EXOC7 Proteins) and MMP-9 (show MMP9 Proteins) in HCC (show FAM126A Proteins) cells was detected and their relations with the ability of migration and invasion of hepatoma carcinoma cells were evaluated

  10. miR (show MLXIP Proteins)-542-3p inhibits the invasion of colorectal cancer cells by targeting CTTN.

Zebrafish Cortactin (CTTN) interaction partners

  1. our data suggest that cortactin and Arp2/3 mediated actin polymerization is implicated in the cell movement during gastrulation and perhaps the development of the central neural system as well.

Cortactin (CTTN) Protein Profile

Protein Summary

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Alternative names and synonyms associated with Cortactin (CTTN)

  • cortactin (CTTN)
  • cortactin (Cttn)
  • cortactin (cttn)
  • src substrate cortactin (CpipJ_CPIJ006351)
  • Src substrate cortactin (Bm1_57220)
  • cortactin (LOC100533277)
  • CG3637 gene product from transcript CG3637-RD (Cortactin)
  • 1110020L01Rik protein
  • CG3637 protein
  • cortactin protein
  • cttn protein
  • CTTN1 protein
  • Cttnb protein
  • Dmel\CG3637 protein
  • EMS1 protein
  • P85.25 protein

Protein level used designations for Cortactin Proteins (CTTN)

cortactin , src substrate cortactin , Src substrate cortactin , src substrate cortactin-like , CG3637-PA , CG3637-PB , CG3637-PC , CG3637-PD , Cortactin-PA , Cortactin-PB , Cortactin-PC , Cortactin-PD , DCortactin , mammary tumor and squamous cell carcinoma associated (p80/85 src substrate) , p80 , p80/85 , src substrate protein p85 , 1110020L01Rik , amplaxin , ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate) , oncogene EMS1 , cortactin isoform B

GENE ID SPECIES
100147634 Equus caballus
399111 Xenopus laevis
451391 Pan troglodytes
496771 Xenopus (Silurana) tropicalis
708291 Macaca mulatta
6038044 Culex quinquefasciatus
6106326 Brugia malayi
100038122 Xenopus (Silurana) tropicalis
100174046 Pongo abelii
100337860 Oryctolagus cuniculus
100411333 Callithrix jacchus
100466994 Ailuropoda melanoleuca
100533277 Aplysia californica
42491 Drosophila melanogaster
13043 Mus musculus
506939 Bos taurus
396455 Gallus gallus
2017 Homo sapiens
60465 Rattus norvegicus
445561 Danio rerio
444298 Xenopus laevis
610283 Canis lupus familiaris
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