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Browse our Cortactin Proteins (CTTN)

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Cortactin Proteins (CTTN)
On www.antibodies-online.com are 6 Cortactin (CTTN) Proteins from 3 different suppliers available. Additionally we are shipping Cortactin Antibodies (216) and Cortactin Kits (15) and many more products for this protein. A total of 255 Cortactin products are currently listed.
Synonyms:
1110020L01Rik, CG3637, cortactin, cttn, CTTN1, Cttnb, Dmel\CG3637, EMS1, P85.25
list all proteins Gene Name GeneID UniProt
CTTN 13043 Q60598
CTTN 2017 Q14247
Rat CTTN CTTN 60465  

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Cortactin Proteins (CTTN) by Origin

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More Proteins for Cortactin Interaction Partners

Mouse (Murine) Cortactin (CTTN) interaction partners

  1. findings reveal that Keap1 (show KEAP1 Proteins) regulates cell migration by affecting the subcellular localization and activity of cortactin independently of its role in oxidant stress responses.

  2. association of cortactin with Pfn-1 (show PFN1 Proteins) is regulated by c-Abl (show ABL1 Proteins)-mediated cortactin phosphorylation

  3. Cell proliferation, migration and invasion were inhibited by genetic knockdown of EMS1.

  4. our findings suggest that after GnRHa activation, src activity leads to tyrosine phosphorylation of cortactin, which facilitates its association with Arp3 to engage the actin cytoskeleton.

  5. GIT1-cortactin association through GIT1-Spa (show FASL Proteins) homology domain is required for cortactin localization to the leading edge and is essential for endothelial cell directional migration and tumor angiogenesis.

  6. Data indicate that cortactin as an Src (show SRC Proteins)-dependent interacting partner of EB1 (show MAPRE1 Proteins).

  7. Introduction of three 4-R-hydroxyproline residues stabilizes the SH3m-cortactin binding of HPK1 (show MAP4K1 Proteins) peptide.

  8. mXinalpha together with cortactin is able to modulate the p120-catenin (show CTNND1 Proteins) activity for shape change and adhesion at the intercalated discs.

  9. the formation of lamellipodia is mediated by a complex of cortactin, CD2AP (show Cd2ap Proteins), and actin capping protein (show TMOD4 Proteins)

  10. FAK (show PTK2 Proteins)-mediated focal adhesion remodeling may occur through the formation of a FAK (show PTK2 Proteins)-cortactin signaling complex.

Cow (Bovine) Cortactin (CTTN) interaction partners

  1. These findings suggest that this common cortactin variant may functionally contribute to ALI predisposition by impeding endothelial wound healing.

Human Cortactin (CTTN) interaction partners

  1. Cortactin expression in epithelial ovarian carcinoma was closely related to malignant biological behavior

  2. the MCP1 (show CCL2 Proteins)-induced cortactin phosphorylation is dependent on PLCb3-mediated PKC (show PRRT2 Proteins) activation, and siRNA-mediated down-regulation of either of these molecules prevents cortactin interaction with WAVE2 (show WASF2 Proteins)

  3. findings reveal that Keap1 (show KEAP1 Proteins) regulates cell migration by affecting the subcellular localization and activity of cortactin independently of its role in oxidant stress responses.

  4. Host cortactin, PKD1 and actin are recruited by Trypanosoma cruzi extracellular amastigotes based on experiments in fixed and live cells by time lapse confocal microscopy.

  5. Study highlights the potential role of CCM3 (show PDCD10 Proteins) in regulating tight junction complex organization and brain endothelial barrier permeability through CCM3 (show PDCD10 Proteins)-ERK1/2-cortactin cross-talk

  6. We identified and confirmed that Fra-1 (show FOSL1 Proteins) affected the expression level of CTTN and EZR (show EZR Proteins) in vitro through LC-MS/MS analyses and western blot technology.

  7. acetylation-mimicking mutants of alpha-tubulin (show TUBA4A Proteins) and cortactin counteract HDAC6 (show HDAC6 Proteins)-induced ciliary disassembly.

  8. cortactin is crucial in invasion and migration of glioma cells, which may promote the migration and invasion of glioma cells by regulating lamellipodia formation, a process requiring the combination of cortactin and the Arp2 (show ACTR2 Proteins)/3 complex

  9. Findings show CTTN significantly upregulated in colon cancer, while its ectopic expression promotes cell proliferation and tumorigenicity through EGFR (show EGFR Proteins)-ERK (show EPHB2 Proteins) pathway regulation suggesting that CTTN plays an important role in colon cancer progression.

  10. The results indicate that cortactin is involved in the regulation of apoptosis induced by VacA in gastric cells.

Zebrafish Cortactin (CTTN) interaction partners

  1. our data suggest that cortactin and Arp2/3 mediated actin polymerization is implicated in the cell movement during gastrulation and perhaps the development of the central neural system as well.

Cortactin (CTTN) Protein Profile

Protein Summary

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Alternative names and synonyms associated with Cortactin (CTTN)

  • cortactin (CTTN)
  • cortactin (Cttn)
  • cortactin (cttn)
  • src substrate cortactin (CpipJ_CPIJ006351)
  • Src substrate cortactin (Bm1_57220)
  • cortactin (LOC100533277)
  • CG3637 gene product from transcript CG3637-RD (Cortactin)
  • 1110020L01Rik protein
  • CG3637 protein
  • cortactin protein
  • cttn protein
  • CTTN1 protein
  • Cttnb protein
  • Dmel\CG3637 protein
  • EMS1 protein
  • P85.25 protein

Protein level used designations for Cortactin Proteins (CTTN)

cortactin , src substrate cortactin , Src substrate cortactin , src substrate cortactin-like , CG3637-PA , CG3637-PB , CG3637-PC , CG3637-PD , Cortactin-PA , Cortactin-PB , Cortactin-PC , Cortactin-PD , DCortactin , mammary tumor and squamous cell carcinoma associated (p80/85 src substrate) , p80 , p80/85 , src substrate protein p85 , 1110020L01Rik , amplaxin , ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate) , oncogene EMS1 , cortactin isoform B

GENE ID SPECIES
100147634 Equus caballus
399111 Xenopus laevis
451391 Pan troglodytes
496771 Xenopus (Silurana) tropicalis
708291 Macaca mulatta
6038044 Culex quinquefasciatus
6106326 Brugia malayi
100038122 Xenopus (Silurana) tropicalis
100174046 Pongo abelii
100337860 Oryctolagus cuniculus
100411333 Callithrix jacchus
100466994 Ailuropoda melanoleuca
100533277 Aplysia californica
42491 Drosophila melanogaster
13043 Mus musculus
506939 Bos taurus
396455 Gallus gallus
2017 Homo sapiens
60465 Rattus norvegicus
445561 Danio rerio
444298 Xenopus laevis
610283 Canis lupus familiaris
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