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Browse our anti-GJA1 (GJA1) Antibodies

Full name:
anti-Gap Junction Protein, alpha 1, 43kDa Antibodies (GJA1)
On are 302 Gap Junction Protein, alpha 1, 43kDa (GJA1) Antibodies from 30 different suppliers available. Additionally we are shipping GJA1 Kits (65) and GJA1 Proteins (10) and many more products for this protein. A total of 391 GJA1 products are currently listed.
AI118175, AU042049, AVSD3, AW546267, Cnx32, Cnx43, Cnx46, connexin43, connexin 43, Cx32, CX43, cx43a1, Cx43alpha1, Cx46, DFNB38, Gja-1, Gja-3, gja1, gja1-A, GJAL, Gjb-1, HLHS1, HSS, Npm1, ODDD, zfCx43.3
list all antibodies Gene Name GeneID UniProt
GJA1 14609 P23242
Anti-Rat GJA1 GJA1 24392 P08050
GJA1 2697 P17302

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Top referenced anti-GJA1 Antibodies

  1. Human Polyclonal GJA1 Primary Antibody for IHC (p), WB - ABIN388369 : Li, Zhang, Jiao, Zou: Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction. in Microvascular research 2009 (PubMed)
    Show all 9 references for ABIN388369

  2. Chicken Monoclonal GJA1 Primary Antibody for IHC (f), IF - ABIN967717 : Giepmans, Hengeveld, Postma, Moolenaar: Interaction of c-Src with gap junction protein connexin-43. Role in the regulation of cell-cell communication. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN967717

  3. Human Polyclonal GJA1 Primary Antibody for EIA, IHC (p) - ABIN357085 : Spinella, Rosanò, Di Castro, Nicotra, Natali, Bagnato: Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN357085

  4. Dog (Canine) Polyclonal GJA1 Primary Antibody for WB - ABIN372602 : Aronica, Gorter, Jansen, Leenstra, Yankaya, Troost: Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex. in Acta neuropathologica 2001 (PubMed)

  5. Dog (Canine) Polyclonal GJA1 Primary Antibody for WB - ABIN452424 : de la Parra, Zenteno: A new GJA1 (connexin 43) mutation causing oculodentodigital dysplasia associated to uncommon features. in Ophthalmic genetics 2007 (PubMed)

  6. Human Polyclonal GJA1 Primary Antibody for ELISA, WB - ABIN1532837 : Boengler, Schulz, Heusch: Connexin 43 signalling and cardioprotection. in Heart (British Cardiac Society) 2006 (PubMed)

  7. Cow (Bovine) Polyclonal GJA1 Primary Antibody for WB - ABIN2774853 : Gellhaus, Dong, Propson, Maass, Klein-Hitpass, Kibschull, Traub, Willecke, Perbal, Lye, Winterhager: Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells. in The Journal of biological chemistry 2004 (PubMed)

  8. Human Polyclonal GJA1 Primary Antibody for IHC, ELISA - ABIN1531561 : Fishman, Eddy, Shows, Rosenthal, Leinwand: The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. in Genomics 1991 (PubMed)

  9. Cow (Bovine) Polyclonal GJA1 Primary Antibody for WB - ABIN2774852 : Feller, Wood, Sluiter, Noffke, Raubenheimer, Lemmer, van Rensburg: Report of a black South African child with oculodentodigital dysplasia and a novel GJA1 gene mutation. in American journal of medical genetics. Part A 2008 (PubMed)

More Antibodies against GJA1 Interaction Partners

Zebrafish Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. Data show that Connexin43 (Cx43) was identified as the gene causing the short-of-fin (sof) phenotype, in which the fin ray segments are shorter but the vertebrae are normal.

  2. serpinh1b is molecularly and functionally downstream of cx43. The gene serpinh1b codes for a protein called Hsp47, a molecular chaperone (show HSP90AA1 Antibodies) responsible for proper folding of procollagen molecules.

  3. Hapln1a (show HAPLN1 Antibodies)-ECM (show MMRN1 Antibodies) stabilizes the secreted growth factor (show WNT2 Antibodies) Semaphorin3d (Sema3d (show SEMA3D Antibodies)), which has been independently shown to mediate Cx43 dependent phenotypes during regeneration.

  4. Hapln1a (show HAPLN1 Antibodies) has a critical role in connexin43-dependent growth and patterning in the regenerating fin skeleton

  5. Sema3d (show SEMA3D Antibodies) functions in a common molecular pathway with Cx43 cell proliferation and joint formation

  6. Data show that the cultured fibroblasts from patients with ossification of the posterior longitudinal ligament (OPLL (show COL6A1 Antibodies)) exhibited osteogenic characteristics, in which Cx43 played an important role.

  7. Studies indicate that Cardiomyogenesis is determined by stimuli from the cellular microenvironment, where connexin43 may play an important role.

  8. Data demonstrate a cross-talk between IGF-1R (show IGF1R Antibodies) and AT-1R in AT-II and IGF-1 (show IGF1 Antibodies)-induced Cx43 expression in SV SMCs involving Erk 1 (show MAPK3 Antibodies)/2 and downstream activation of the AP-1 (show JUN Antibodies) transcription factor.

  9. Gap junctional intercellular communication in human bladder smooth muscle cells and suburothelial myofibroblastsdepend of Cx43 rather than on Cx45 (show GJC1 Antibodies).

  10. Critical role of connexin43 in zebrafish late primitive and definitive hematopoiesis.

Rabbit Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. These findings indicated that Cx43/miR (show MYLIP Antibodies)-206 is involved in the pathogenesis of early stage steroid-induced avascular necrosis of the femoral head.

  2. Gap junction enhancer AAP10 could attenuate the pro-arrhythmic effect of lysophosphatidic acid, probably by downregulating myocardial nonphosphorylated Cx43 expression.

  3. Ischemic postconditioning protected the heart from I/R injury by attenuating I/R induced decrease of mitochondria Cx43 expression.

  4. In addition to Cx43 dephosphorylation, downregulation of Cx43 plays an essential role in reduced cell coupling in the failing rabbit heart

Mouse (Murine) Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. beige (show LYST Antibodies) adipocytes display an increased cell-to-cell coupling via connexin 43 (Cx43) gap junction channels.

  2. intermittent hypoxia (but not sleep fragmentation) causes reductions and remodeling of atrial Cx40 (show GJA5 Antibodies) and Cx43.

  3. the expression of Cx43 is specifically required in lymphatic endothelial cells for normal development of Lymphatic valves.

  4. This study showed that Gja1 may act downstream of cAMP-PKA signal to mediate the effects of Acvr1 (show ACRV1 Antibodies) on the differentiation of uterine stromal cells through targeting Hand2 (show HAND2 Antibodies).

  5. Results indicate that pre- and peri (show POSTN Antibodies)-implantation development does not require connexin43 (Cx43) and connexin45 (Cx45 (show GJC1 Antibodies)).

  6. no statistically significant difference in connexin43 expression between fetal day 13 mice and adults

  7. Cx43 can communicate cylic AMP (show TMPRSS5 Antibodies) (cAMP) between cells and, more importantly, that the communicated cAMP is sufficient to impact signal transduction cascades and the expression of key bone effector molecules between interconnected cells.

  8. The results of this study indicated that the Leu89Pro substitution in the second transmembrane domain of CX32 (show GJB1 Antibodies) disrupts the trafficking of the protein, inhibiting the assembly of CX32 (show GJB1 Antibodies) gap junctions, which in turn may result in peripheral neuropathy.

  9. The results identify new protein-protein interactions between AIF (show AIFM1 Antibodies)-Cx43, ETFB (show ETFB Antibodies)-Cx43 and AIF (show AIFM1 Antibodies)-ETFB (show ETFB Antibodies) as possible players in the regulation of the mitochondrial redox state.

  10. Data show that in the presence of heterogeneous connexin 43 (Cx43) expression, ephaptic coupling can either prevent or promote conduction block (CB) depending on the Cx43 knockout (Cx43KO) content.

Guinea Pig Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. The localization and distribution of gap junction (GJ) intercellular channels and connexin 43 (Cx43) in cells surrounding spiral ganglion cell bodies in man and guinea pig, were analyzed.

  2. CX43 is therefore essential for the maintenance of spontaneous slow wave activity and subsequent contractile activity in the guinea pig prostate gland.

Cow (Bovine) Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. This study found that down-regulation of Cx43 expression in the junction zone might play an important role in pathogenesis of adenomyosis, and that estradiol modulates gap junctions during adenomyosis.

  2. Cx43 mRNA and protein expression increased after endothelial cell exposure to ketone bodies; this was accompanied by upregulation of gap junctional intercellular coupling and cell migration.

  3. RhoA (show RHOA Antibodies) appears to be an important molecular switch that controls Cx43 hemichannel openings and hemichannel-mediated ATP-dependent paracrine intercellular communication under (patho)physiological conditions of stress

  4. Papillary urothelial carcinomas showed moderate cytoplasmic and membrane labelling, while invasive carcinoma showed loss of connexin 43 expression.

  5. Human TGF-beta1 (show TGFB1 Antibodies) induces an accumulation of connexin43 in a lysosomal compartment in bovine endothelial cells

  6. Increased degradation of Cx43 and reduction of intracellular communication through gap junctions in high glucose may be of physiological importance by contributing to endothelial cell dysfunction.

  7. intermediate invasive status of bovine trophoblast is supported by the fact that trophoblast giant cells coexpress connexins (Cx)26 (show GJB2 Antibodies), Cx32 (show GJB1 Antibodies), and Cx43

  8. CBN (show CALB1 Antibodies) blocks junctional communication and modulates Cx43 expression in BAEC. These results suggest a feedback mechanism for control of connexin expression based on junctional patency.

  9. Results describe the effect of suppression of connexin 43 and E-cadherin (show CDH1 Antibodies) on the development, mRNA and protein expression of bovine blastocysts cultured in vitro or in vivo.

Human Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. Results suggest polymorphisms of Cx37 (show GJA4 Antibodies) rs1630310 and Cx43 rs1925223 genes may be associated with the pathogenesis of essential hypertension.

  2. The Cx43 is the most prominent gap junction protein in the heart, cardiomyocyte-differentiated stem cells have been studied intensely. Cx43 expression was detected at mRNA and protein level in human cord-blood-derived induced pluripotent stem cells .

  3. Human deltoid muscle biopsies of 5 Chilean dysferlinopathy patients exhibited the presence of muscular connexins (Cx40.1, Cx43 and Cx45 (show GJC1 Antibodies)).

  4. endogenous osteocyte Cx43 hemichannels emerge as important and promising therapeutic targets for the prevention of bone metastases and/or clinical treatment of bone-metastasized breast cancers

  5. The results suggest that Osterix (show SP7 Antibodies) plays an important role in increasing BMP- 4 (show BMP4 Antibodies)-induced Cx43 activity.

  6. Study demonstrates that myocardin (show MYOCD Antibodies) indirectly down-regulates Cx43 through its repressive action on miR (show MLXIP Antibodies)-206 to regulate vascular smooth muscle cell phenotypic switch.

  7. RXRalpha (show RXRA Antibodies) negatively regulates the transcription and expression by directly binding to the RARE in the promoter of Cx43

  8. Connexin 43 might contribute to the stabilization of atheromatous plaque which is affected by oxidative stress.

  9. Results provide evidence that abnormal high expression and cytoplasmic localization of Cx43 contributed to bladder cancer.

  10. Data show that connexin-43 (Cx43) influences the mitochondria control of the cell death pathway in SH-SY5Y Neuroblastoma (show ARHGEF16 Antibodies) cells.

Pig (Porcine) Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. Data show that connexin 43 (Cx43) is localized in the ooplasmic membrane through zona pellucidae and its level changes over time during culture in porcine oocytes.

  2. The effects of flutamide on connexin 43 expression in porcine placenta and uterus throughout pregnancy are reported.

  3. we demonstrated that modulation of Cx43 expression in the prostate could serve as a sensitive marker of hormonal disruption during different developmental stages.

  4. The in vitro cultivation of cumulus cells was associated with cell proliferation and that Cx43 and Cdk4 (show CDK4 Antibodies) gene expression was upregulated after in vitro cultivation, resulting in significantly higher protein levels.

  5. Gonadotropins regulate Cx43 protein expression, degradation and localization in porcine cumulus oocyte complex.

  6. Gene transfer-mediated overexpression of Cx43 increases the absolute amount of phosphorylated and intercalated disk-localized Cx43, improves conduction velocity (CV), and reduces ventricular tachycardia inducibility.

  7. These data suggest that neonatal exposure to flutamide induces long-term effects on the spermatogenic capacity of the pig testis through alterations of Cx43-mediated intercellular communication.

  8. Cx43 expression and distribution are disrupted by ischemia, recovered by the well reperfused regions and further disrupted by no-reflow.

  9. Atrial connexin 43 was reduced in atrial fibrillation. Connexin 43 gene therapy prevented persistent atrial fibrillation.

  10. During ventricular fibrillation, myocardial Cx43 expression was down-regulated, which could be attenuated by administration of ZP123.

GJA1 Antigen Profile

Antigen Summary

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations.

Alternative names and synonyms associated with GJA1

  • gap junction protein, alpha 1, 43kDa (gja1) antibody
  • connexin 43 (cx43) antibody
  • connexin 43 (CX43) antibody
  • CONNEXIN 43 protein (CONNEXIN 43) antibody
  • connexin 43-like (LOC100359132) antibody
  • gap junction protein, alpha 1 (Gja1) antibody
  • gap junction protein, alpha 1, 43kDa (GJA1) antibody
  • gap junction protein, alpha 3 (Gja3) antibody
  • gap junction protein, beta 1 (Gjb1) antibody
  • AI118175 antibody
  • AU042049 antibody
  • AVSD3 antibody
  • AW546267 antibody
  • Cnx32 antibody
  • Cnx43 antibody
  • Cnx46 antibody
  • connexin43 antibody
  • connexin 43 antibody
  • Cx32 antibody
  • CX43 antibody
  • cx43a1 antibody
  • Cx43alpha1 antibody
  • Cx46 antibody
  • DFNB38 antibody
  • Gja-1 antibody
  • Gja-3 antibody
  • gja1 antibody
  • gja1-A antibody
  • GJAL antibody
  • Gjb-1 antibody
  • HLHS1 antibody
  • HSS antibody
  • Npm1 antibody
  • ODDD antibody
  • zfCx43.3 antibody

Protein level used designations for GJA1

alpha 1 gap junction protein , connexin 43 , connexin-43 , etID309742.9 , gap junction alpha-1 protein , gap junction protein, alpha 1 , shf , short fin protein , sof , alpha 1 connexin , gap junction 43 kDa heart protein , gap junction membrane channel protein alpha 1 , cx43 , gap junction protein, alpha 1, 43 kD (connexin 43) , vascular smooth muscle connexin-43 , gap junction protein, alpha 1, 43kDa (connexin 43) , Connexin-43 , gap junction protein alpha 1 , gap junction protein, alpha 1, 43kDa , alpha 3 connexin , connexin-46 , gap junction alpha-3 protein , gap junction membrane channel protein alpha 3 , connexin 32 , connexin-32 , gap junction beta-1 protein , gap junction membrane channel protein beta 1

394450 Xenopus (Silurana) tropicalis
30236 Danio rerio
100067229 Equus caballus
443455 Ovis aries
100359132 Oryctolagus cuniculus
14609 Mus musculus
24392 Rattus norvegicus
100379273 Cavia porcellus
281193 Bos taurus
2697 Homo sapiens
403418 Canis lupus familiaris
100518636 Sus scrofa
100008935 Oryctolagus cuniculus
373664 Xenopus laevis
395278 Gallus gallus
443233 Ovis aries
101100211 Felis catus
14611 Mus musculus
14618 Mus musculus
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