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Browse our anti-GJA1 (GJA1) Antibodies

Full name:
anti-Gap Junction Protein, alpha 1, 43kDa Antibodies (GJA1)
On www.antibodies-online.com are 280 Gap Junction Protein, alpha 1, 43kDa (GJA1) Antibodies from 27 different suppliers available. Additionally we are shipping GJA1 Kits (62) and GJA1 Proteins (11) and many more products for this protein. A total of 368 GJA1 products are currently listed.
Synonyms:
AI118175, AU042049, AVSD3, AW546267, Cnx32, Cnx43, Cnx46, connexin43, connexin 43, Cx32, CX43, cx43a1, Cx43alpha1, Cx46, DFNB38, Gja-1, Gja-3, gja1, gja1-A, GJAL, Gjb-1, HLHS1, HSS, Npm1, ODDD, zfCx43.3
list all antibodies Gene Name GeneID UniProt
GJA1 14609 P23242
Anti-Rat GJA1 GJA1 24392 P08050
GJA1 2697 P17302

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Top referenced anti-GJA1 Antibodies

  1. Human Polyclonal GJA1 Primary Antibody for IHC (p), WB - ABIN388369 : Li, Zhang, Jiao, Zou: Knockdown of microRNA-181 by lentivirus mediated siRNA expression vector decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction. in Microvascular research 2009 (PubMed)
    Show all 9 references for ABIN388369

  2. Chicken Monoclonal GJA1 Primary Antibody for IHC (f), IF - ABIN967717 : Giepmans, Hengeveld, Postma, Moolenaar: Interaction of c-Src with gap junction protein connexin-43. Role in the regulation of cell-cell communication. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN967717

  3. Human Polyclonal GJA1 Primary Antibody for EIA, IHC (p) - ABIN357085 : Spinella, Rosanò, Di Castro, Nicotra, Natali, Bagnato: Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN357085

  4. Dog (Canine) Polyclonal GJA1 Primary Antibody for IF (p), IHC (p) - ABIN671451 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)
    Show all 2 references for ABIN671451

  5. Dog (Canine) Polyclonal GJA1 Primary Antibody for WB - ABIN452424 : de la Parra, Zenteno: A new GJA1 (connexin 43) mutation causing oculodentodigital dysplasia associated to uncommon features. in Ophthalmic genetics 2007 (PubMed)

  6. Human Polyclonal GJA1 Primary Antibody for ELISA, WB - ABIN1532837 : Boengler, Schulz, Heusch: Connexin 43 signalling and cardioprotection. in Heart (British Cardiac Society) 2006 (PubMed)

  7. Cow (Bovine) Polyclonal GJA1 Primary Antibody for WB - ABIN2774853 : Gellhaus, Dong, Propson, Maass, Klein-Hitpass, Kibschull, Traub, Willecke, Perbal, Lye, Winterhager: Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells. in The Journal of biological chemistry 2004 (PubMed)

  8. Human Polyclonal GJA1 Primary Antibody for IHC, ELISA - ABIN1531561 : Fishman, Eddy, Shows, Rosenthal, Leinwand: The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. in Genomics 1991 (PubMed)

  9. Dog (Canine) Polyclonal GJA1 Primary Antibody for WB - ABIN2774852 : Feller, Wood, Sluiter, Noffke, Raubenheimer, Lemmer, van Rensburg: Report of a black South African child with oculodentodigital dysplasia and a novel GJA1 gene mutation. in American journal of medical genetics. Part A 2008 (PubMed)

More Antibodies against GJA1 Interaction Partners

Zebrafish Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. serpinh1b is molecularly and functionally downstream of cx43. The gene serpinh1b codes for a protein called Hsp47, a molecular chaperone (show HSP90AA1 Antibodies) responsible for proper folding of procollagen molecules.

  2. Hapln1a (show HAPLN1 Antibodies)-ECM (show MMRN1 Antibodies) stabilizes the secreted growth factor (show WNT2 Antibodies) Semaphorin3d (Sema3d (show SEMA3D Antibodies)), which has been independently shown to mediate Cx43 dependent phenotypes during regeneration.

  3. Hapln1a (show HAPLN1 Antibodies) has a critical role in connexin43-dependent growth and patterning in the regenerating fin skeleton

  4. Sema3d (show SEMA3D Antibodies) functions in a common molecular pathway with Cx43 cell proliferation and joint formation

  5. Data show that the cultured fibroblasts from patients with ossification of the posterior longitudinal ligament (OPLL (show COL6A1 Antibodies)) exhibited osteogenic characteristics, in which Cx43 played an important role.

  6. Studies indicate that Cardiomyogenesis is determined by stimuli from the cellular microenvironment, where connexin43 may play an important role.

  7. Data demonstrate a cross-talk between IGF-1R (show IGF1R Antibodies) and AT-1R in AT-II and IGF-1 (show IGF1 Antibodies)-induced Cx43 expression in SV SMCs involving Erk 1 (show MAPK3 Antibodies)/2 and downstream activation of the AP-1 (show JUN Antibodies) transcription factor.

  8. Gap junctional intercellular communication in human bladder smooth muscle cells and suburothelial myofibroblastsdepend of Cx43 rather than on Cx45 (show GJC1 Antibodies).

  9. Critical role of connexin43 in zebrafish late primitive and definitive hematopoiesis.

  10. Cx43 is crucial for TJ reassembly at the blood-testis barrier during its cyclic restructuring throughout the seminiferous epithelial cycle of spermatogenesis

Rabbit Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. Gap junction enhancer AAP10 could attenuate the pro-arrhythmic effect of lysophosphatidic acid, probably by downregulating myocardial nonphosphorylated Cx43 expression.

  2. Ischemic postconditioning protected the heart from I/R injury by attenuating I/R induced decrease of mitochondria Cx43 expression.

  3. In addition to Cx43 dephosphorylation, downregulation of Cx43 plays an essential role in reduced cell coupling in the failing rabbit heart

Mouse (Murine) Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. The results suggest an involvement of Cx43 in the psychosine-mediated apoptosis of primary oligodendrocyte progenitors from wild type or Krabbe disease twitcher (show GALC Antibodies) mice.

  2. antigens present on bone marrowderived dendritic cell (BMDCs) can be suppressed by connexin43 knockdown in BMDCs.

  3. CX43 might represent an important regulator of dynamic Blood-testis barrier formation, composition and function.[review]

  4. Cx43 in astrocytes plays a critical role in neuro-inflammatory responses

  5. the important roles of androgen receptor (show AR Antibodies) and Connexin 43 actions in the regulation of follicular development

  6. Data show that segregation of Foxc2 (show FOXC2 Antibodies) and NFATc1 (show NFATC1 Antibodies) transcription factor is closely associated with the highly polarized expression of connexins Cx37 (show GJA4 Antibodies), Cx43, and Cx47 (show GJC2 Antibodies).

  7. increased acetylation of Cx43 in the left ventricles of dogs subjected to chronic tachypacing as abnormal ventricular activation... altered electrical activity can regulate cardiomyocyte communication by influencing the acetylation status of Cx43

  8. We conclude that Cx43 CT domain is involved in proper bone acquisition; and that Cx43 expression in osteocytes is dispensable for some but not all PTH (show PTH Antibodies) anabolic actions.

  9. administration of 0.3 IU/mL FSH (show BRD2 Antibodies) during ovarian cryopreservation by vitrification can maintain ovarian survival during ovarian vitrification and increases the blood supply with avascular transplantation via upregulation of Cx43, Cx37 (show GJA4 Antibodies), and VEGF (show VEGFA Antibodies)/VEGFR2 (show KDR Antibodies)

  10. Cardiomyocyte-specific overexpression of Wwp1 (show WWP1 Antibodies) contributes to reduction in Connexin 43 and arrhythmogenesis.

Guinea Pig Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. The localization and distribution of gap junction (GJ) intercellular channels and connexin 43 (Cx43) in cells surrounding spiral ganglion cell bodies in man and guinea pig, were analyzed.

  2. CX43 is therefore essential for the maintenance of spontaneous slow wave activity and subsequent contractile activity in the guinea pig prostate gland.

Cow (Bovine) Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. Cx43 mRNA and protein expression increased after endothelial cell exposure to ketone bodies; this was accompanied by upregulation of gap junctional intercellular coupling and cell migration.

  2. RhoA (show RHOA Antibodies) appears to be an important molecular switch that controls Cx43 hemichannel openings and hemichannel-mediated ATP-dependent paracrine intercellular communication under (patho)physiological conditions of stress

  3. Papillary urothelial carcinomas showed moderate cytoplasmic and membrane labelling, while invasive carcinoma showed loss of connexin 43 expression.

  4. Human TGF-beta1 (show TGFB1 Antibodies) induces an accumulation of connexin43 in a lysosomal compartment in bovine endothelial cells

  5. Increased degradation of Cx43 and reduction of intracellular communication through gap junctions in high glucose may be of physiological importance by contributing to endothelial cell dysfunction.

  6. intermediate invasive status of bovine trophoblast is supported by the fact that trophoblast giant cells coexpress connexins (Cx)26 (show GJB2 Antibodies), Cx32 (show GJB1 Antibodies), and Cx43

  7. CBN (show CALB1 Antibodies) blocks junctional communication and modulates Cx43 expression in BAEC. These results suggest a feedback mechanism for control of connexin expression based on junctional patency.

  8. Results describe the effect of suppression of connexin 43 and E-cadherin (show CDH1 Antibodies) on the development, mRNA and protein expression of bovine blastocysts cultured in vitro or in vivo.

Human Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. Our data suggest a mechanism by which CT-Cx43 may regulate cell proliferation by regulating mir (show MLXIP Antibodies)-125b and p53 (show TP53 Antibodies) expression

  2. we are the first to identify that miR (show MLXIP Antibodies)-381 suppresses C/EBPalpha (show CEBPA Antibodies)-dependent Cx43 expression in breast cancer cells. The miR (show MLXIP Antibodies)-381-C/EBPalpha (show CEBPA Antibodies)-Cx43 axis might be a useful diagnostic and therapeutic target of metastatic breast cancer

  3. Cx43-Hsc70 (show HSPA8 Antibodies) interaction regulates cell cycle G1/S progression through a novel mechanism by which Cx43-Hsc70 (show HSPA8 Antibodies) interaction prevents the nuclear accumulation of p27 (show PAK2 Antibodies) through controlling the nuclear translocation of cyclin D1 (show CCND1 Antibodies)-CDK4 (show CDK4 Antibodies)-p27 (show PAK2 Antibodies) complex.

  4. local regulation of endothelial Cx43 expression within the vasculature regulates monocyteendothelial adhesion.

  5. demonstrate a specific role of the upstream DNA methylation (show HELLS Antibodies)/miR (show MLXIP Antibodies)-1298/Connexin 43 pathway in regulating VSMC function

  6. Taken together, in Jar (show MYO6 Antibodies) cells, placental connexins 43 and 46 are regulated during periods of low oxygen in opposite manners

  7. AR pathway plays an important role in regulation of CX43 expression in prostate cancer cells. AR may be the upstream signal of CX43.

  8. The data indicate for the first time that increased cytoplasmic human papillomavirus type 16 E6 levels associated with malignant progression alter Cx43 trafficking and recycling to the membrane and the E6/human Dlg (show DLG4 Antibodies) interaction may be involved.

  9. high glucose disassociated interactions between Cx43 and tight junctions, and then increased airway epithelial transepithelial electrical resistance and permeability by down-regulation of Cx43 in human airway epithelial cells.

  10. Data show that both connexin 43 (Cx43) expression and gap junctional intercellular communication (GJIC (show GJB1 Antibodies)) function were increased by All-trans retinoic acid (ATRA) treatment.

Pig (Porcine) Gap Junction Protein, alpha 1, 43kDa (GJA1) interaction partners

  1. The effects of flutamide on connexin 43 expression in porcine placenta and uterus throughout pregnancy are reported.

  2. we demonstrated that modulation of Cx43 expression in the prostate could serve as a sensitive marker of hormonal disruption during different developmental stages.

  3. The in vitro cultivation of cumulus cells was associated with cell proliferation and that Cx43 and Cdk4 (show CDK4 Antibodies) gene expression was upregulated after in vitro cultivation, resulting in significantly higher protein levels.

  4. Gonadotropins regulate Cx43 protein expression, degradation and localization in porcine cumulus oocyte complex.

  5. Gene transfer-mediated overexpression of Cx43 increases the absolute amount of phosphorylated and intercalated disk-localized Cx43, improves conduction velocity (CV), and reduces ventricular tachycardia inducibility.

  6. These data suggest that neonatal exposure to flutamide induces long-term effects on the spermatogenic capacity of the pig testis through alterations of Cx43-mediated intercellular communication.

  7. Cx43 expression and distribution are disrupted by ischemia, recovered by the well reperfused regions and further disrupted by no-reflow.

  8. Atrial connexin 43 was reduced in atrial fibrillation. Connexin 43 gene therapy prevented persistent atrial fibrillation.

  9. During ventricular fibrillation, myocardial Cx43 expression was down-regulated, which could be attenuated by administration of ZP123.

  10. These results indicate that changes of Cx43 expression in the porcine myometrium during the oestrous cycle may be regulated by progesterone concentration and may contribute to the modulation of uterine motility.

GJA1 Antigen Profile

Antigen Summary

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations.

Alternative names and synonyms associated with GJA1

  • gap junction protein, alpha 1, 43kDa (gja1) antibody
  • connexin 43 (cx43) antibody
  • connexin 43 (CX43) antibody
  • CONNEXIN 43 protein (CONNEXIN 43) antibody
  • connexin 43-like (LOC100359132) antibody
  • gap junction protein, alpha 1 (Gja1) antibody
  • gap junction protein, alpha 1, 43kDa (GJA1) antibody
  • gap junction protein, alpha 3 (Gja3) antibody
  • gap junction protein, beta 1 (Gjb1) antibody
  • AI118175 antibody
  • AU042049 antibody
  • AVSD3 antibody
  • AW546267 antibody
  • Cnx32 antibody
  • Cnx43 antibody
  • Cnx46 antibody
  • connexin43 antibody
  • connexin 43 antibody
  • Cx32 antibody
  • CX43 antibody
  • cx43a1 antibody
  • Cx43alpha1 antibody
  • Cx46 antibody
  • DFNB38 antibody
  • Gja-1 antibody
  • Gja-3 antibody
  • gja1 antibody
  • gja1-A antibody
  • GJAL antibody
  • Gjb-1 antibody
  • HLHS1 antibody
  • HSS antibody
  • Npm1 antibody
  • ODDD antibody
  • zfCx43.3 antibody

Protein level used designations for GJA1

alpha 1 gap junction protein , connexin 43 , connexin-43 , etID309742.9 , gap junction alpha-1 protein , gap junction protein, alpha 1 , shf , short fin protein , sof , alpha 1 connexin , gap junction 43 kDa heart protein , gap junction membrane channel protein alpha 1 , cx43 , gap junction protein, alpha 1, 43 kD (connexin 43) , vascular smooth muscle connexin-43 , gap junction protein, alpha 1, 43kDa (connexin 43) , Connexin-43 , gap junction protein alpha 1 , gap junction protein, alpha 1, 43kDa , alpha 3 connexin , connexin-46 , gap junction alpha-3 protein , gap junction membrane channel protein alpha 3 , connexin 32 , connexin-32 , gap junction beta-1 protein , gap junction membrane channel protein beta 1

GENE ID SPECIES
394450 Xenopus (Silurana) tropicalis
30236 Danio rerio
100067229 Equus caballus
443455 Ovis aries
100359132 Oryctolagus cuniculus
14609 Mus musculus
24392 Rattus norvegicus
100379273 Cavia porcellus
281193 Bos taurus
2697 Homo sapiens
403418 Canis lupus familiaris
100518636 Sus scrofa
100008935 Oryctolagus cuniculus
373664 Xenopus laevis
395278 Gallus gallus
443233 Ovis aries
101100211 Felis catus
14611 Mus musculus
14618 Mus musculus
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