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Browse our MAPK7 Proteins (MAPK7)

Full name:
Mitogen-Activated Protein Kinase 7 Proteins (MAPK7)
On www.antibodies-online.com are 10 Mitogen-Activated Protein Kinase 7 (MAPK7) Proteins from 7 different suppliers available. Additionally we are shipping MAPK7 Antibodies (187) and many more products for this protein. A total of 204 MAPK7 products are currently listed.
Synonyms:
A330097D03Rik, ATMPK7, Bmk1, ERK-5, Erk3, ERK4, Erk5, Erk5-T, F8D23.5, F8D23_5, MAP kinase 7, p63Mapk, Prkm4, Prkm7
list all proteins Gene Name GeneID UniProt
MAPK7 225724 Q6P5G0
Rat MAPK7 MAPK7 54268  
MAPK7 5598 Q13164

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MAPK7 Proteins (MAPK7) by Origin

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More Proteins for MAPK7 Interaction Partners

Mouse (Murine) Mitogen-Activated Protein Kinase 7 (MAPK7) interaction partners

  1. Finally, we demonstrated that miR (show MLXIP Proteins)-24 plays the modulational role by directly repressing MAPK7, a key number in the MAPK (show MAPK1 Proteins) signaling pathway. These data indicate that miR (show MLXIP Proteins)-24 is a novel positive regulator of adipocyte differentiation by targeting MAPK7, which provides new insights into the molecular mechanism of miRNA-mediated cellular differentiation.

  2. the activation of ERK5-AKT (show AKT1 Proteins)-FoxO3a (show FOXO3 Proteins) signaling pathways by fluid shear stress resulted in a decreased expression of FasL (show FASL Proteins) and Bim (show BCL2L11 Proteins) and an inhibition of caspase-3 (show CASP3 Proteins) activation, which exerts a protective effect that prevents osteoblasts from apoptosis.

  3. Data, including data from studies in knockout mice, suggest that Erk5/Mapk7 is required for tobacco smoke-triggered gastric epithelial-mesenchymal transition; can be suppressed by dietary factors (here, supplementation with epigallocatechin-3-gallate); suppression of Erk5/Mapk7 activation reverses tobacco smoke-triggered epithelial-mesenchymal transition in gastric mucosa.

  4. ERK5 activation is essential for osteoclast differentiation.

  5. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.

  6. ERK5 negatively regulates cigarette smoke-mediated pulmonary epithelial mesenchymal transformation.

  7. Our findings define ERK5 as a novel kinase that modulates the levels of TCR/CD3 at the cell surface by promoting CD3zeta degradation and TCR/CD3 recovery after TCR stimulation.

  8. A novel I (show TRAF4 Proteins)L-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.

  9. The ERK5 pathway is essential in the induction of COX-2 gene.

  10. This study reveals a novel role for the ERK5-MEF2 (show MEF2C Proteins) cascade, linking bFGF (show FGF2 Proteins)-induced PAI-1 (show SERPINE1 Proteins) expression and subsequent mitogenic processes in lung fibroblasts.

Human Mitogen-Activated Protein Kinase 7 (MAPK7) interaction partners

  1. miR (show MLXIP Proteins)-200b-3p suppresses glioma tumor growth, invasion, and reverses EMT (show ITK Proteins) through downregulated its target ERK5.

  2. Results indicate that MAPK7 may be modulating the growth, proliferation, migration and invasion of osteosarcoma cells.

  3. Thus ERK5 signaling is unlikely to play a role in tumor cell proliferation downstream of KRAS or BRAF (show BRAF Proteins) or in tumor cells with ERK5 amplification. These results have important implications for the role of ERK5 as an anti-cancer drug target

  4. data implied the up-regulated MAPK7 might contribute to ovarian cancer metastasis

  5. The results pf this study indicated that BMK1 modulation by miR (show MLXIP Proteins)-429 has an important function in glioma invasion both in vitro and in vivo.

  6. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation.

  7. ERK5 negatively regulates cigarette smoke-mediated pulmonary epithelial mesenchymal transformation.

  8. Our findings define ERK5 as a novel kinase that modulates the levels of TCR/CD3 at the cell surface by promoting CD3zeta degradation and TCR/CD3 recovery after TCR stimulation.

  9. we demonstrated for the first time that ERK5 positively regulated CS-mediated EMT (show ITK Proteins) in urothelial cells, as evidenced by the findings that CS promoted ERK5 activation and that the CS-triggered alteration in the EMT (show ITK Proteins) phenotype was reversed by ERK5 inhibition

  10. The TRAF4 (show TRAF4 Proteins)-ERK5 is a dominant pathway in human skin squamous cell carcinoma.

Arabidopsis thaliana Mitogen-Activated Protein Kinase 7 (MAPK7) interaction partners

  1. Data showed that expression of the MKK7 (show MAP2K7 Proteins) gene in wild-type plants is induced by pathogen infection. Reducing mRNA levels of MKK7 (show MAP2K7 Proteins) by antisense RNA expression not only compromises basal resistance, but also blocks the induction of SAR (show SRL Proteins).

MAPK7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Alternative names and synonyms associated with MAPK7

  • mitogen-activated protein kinase 4 (Mapk4)
  • mitogen-activated protein kinase 7 (MAPK7)
  • mitogen-activated protein kinase 7 (Mapk7)
  • mitogen-activated protein kinase 7 (MPK7)
  • A330097D03Rik protein
  • ATMPK7 protein
  • Bmk1 protein
  • ERK-5 protein
  • Erk3 protein
  • ERK4 protein
  • Erk5 protein
  • Erk5-T protein
  • F8D23.5 protein
  • F8D23_5 protein
  • MAP kinase 7 protein
  • p63Mapk protein
  • Prkm4 protein
  • Prkm7 protein

Protein level used designations for MAPK7

ERK-4 , Erk3-related , MAP kinase 4 , MAPK 4 , extracellular signal-regulated kinase 4 , mitogen activated protein kinase 4 , MAP kinase isoform p63 , MNK2 , p63-MAPK , BMK-1 , BMK1 kinase , ERK-5 , MAP kinase 7 , MAPK 7 , big MAP kinase 1 , extracellular signal-regulated kinase 5 , extracellular-signal-regulated kinase 5 , extracellular signal regulated kinase 5 , mitogen activated protein kinase 7 , mitogen-activated kinase 7 , Big MAP kinase 1 , Extracellular signal-regulated kinase 5

GENE ID SPECIES
225724 Mus musculus
54268 Rattus norvegicus
5598 Homo sapiens
23939 Mus musculus
114509 Rattus norvegicus
537703 Bos taurus
816330 Arabidopsis thaliana
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