MAPK7 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all MAPK7 Proteins
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MAPK7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MAPK7 / ERK5 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MAPK7 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
- Alternative Name
- Mapk7,erk5 (MAPK7 Products)
- Synonyms
- BMK1 Protein, ERK4 Protein, ERK5 Protein, PRKM7 Protein, Erk5-T Protein, ATMPK7 Protein, F8D23.5 Protein, F8D23_5 Protein, MAP kinase 7 Protein, Bmk1 Protein, Erk5 Protein, Prkm7 Protein, ERK-5 Protein, bmk1 Protein, erk4 Protein, mapk7 Protein, prkm7 Protein, mitogen-activated protein kinase 7 Protein, MAP kinase 7 Protein, mitogen-activated protein kinase 7 L homeolog Protein, MAPK7 Protein, Mapk7 Protein, MPK7 Protein, mapk7.L Protein
- Background
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
- Molecular Weight
- 88.2 kDa
- NCBI Accession
- NP_002740
- Pathways
- MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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