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Browse our anti-MAPT (MAPT) Antibodies

Full name:
anti-Microtubule-Associated Protein tau Antibodies (MAPT)
On are 1038 Microtubule-Associated Protein tau (MAPT) Antibodies from 36 different suppliers available. Additionally we are shipping MAPT Kits (73) and MAPT Proteins (55) and many more products for this protein. A total of 1209 MAPT products are currently listed.
AI413597, AI426939, AI551861, AW045860, AW457082, CK1epsilon, CKIe, DDPAC, FTDP-17, KC1epsilon, MAPT, MAPTL, MSTD, Mtapt, MTBT1, MTBT2, PHF-tau, PPND, pTau, RNPTAU, Tau, xtp
list all antibodies Gene Name GeneID UniProt
MAPT 27373 Q9JMK2
MAPT 4137 P10636
Anti-Rat MAPT MAPT 29477  

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All available anti-MAPT Antibodies

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Top referenced anti-MAPT Antibodies

  1. Human Polyclonal MAPT Primary Antibody for IF, IHC (p) - ABIN388782 : Yoshiyama, Zhang, Bruce, Trojanowski, Lee: Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 (PubMed)
    Show all 4 references for ABIN388782

  2. Human Polyclonal MAPT Primary Antibody for EIA, IHC (p) - ABIN357423 : Horiguchi, Uryu, Giasson, Ischiropoulos, LightFoot, Bellmann, Richter-Landsberg, Lee, Trojanowski: Nitration of tau protein is linked to neurodegeneration in tauopathies. in The American journal of pathology 2003 (PubMed)
    Show all 4 references for ABIN357423

  3. Human Polyclonal MAPT Primary Antibody for EIA, WB - ABIN356907 : Beck, Rohrer, Campbell, Isaacs, Morrison, Goodall, Warrington, Stevens, Revesz, Holton, Al-Sarraj, King, Scahill, Warren, Fox, Rossor, Collinge, Mead: A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. in Brain : a journal of neurology 2008 (PubMed)
    Show all 3 references for ABIN356907

  4. Human Polyclonal MAPT Primary Antibody for ELISA, WB - ABIN1533027 : Lee, Neve, Kosik: The microtubule binding domain of tau protein. in Neuron 1990 (PubMed)
    Show all 2 references for ABIN1533027

  5. Human Polyclonal MAPT Primary Antibody for ELISA, WB - ABIN1531990 : Andreadis, Brown, Kosik: Structure and novel exons of the human tau gene. in Biochemistry 1992 (PubMed)
    Show all 2 references for ABIN1531990

  6. Human Polyclonal MAPT Primary Antibody for IHC, WB - ABIN2783223 : Reynolds, Lukas, Berry, Binder: Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms. in Biochemistry 2006 (PubMed)

  7. Human Polyclonal MAPT Primary Antibody for IHC (p), WB - ABIN388191 : McCulloch, Kay, Factor, Samii, Nutt, Higgins, Griffith, Roberts, Leis, Montimurro, Zabetian, Payami: Exploring gene-environment interactions in Parkinson's disease. in Human genetics 2008 (PubMed)

More Antibodies against MAPT Interaction Partners

Xenopus laevis Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Suppressing the expression of all tau isoforms disrupted only those neuronal microtubules containing class II beta-tubulin (show TUBB Antibodies), and that boosting the expression of the largest 'big', but not the smallest, tau isoform enhanced neurite outgrowth.

Mouse (Murine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Abeta (show APP Antibodies) monomers physiologically favor Tau activity and dendritic sprouting, whereas their excess causes Tau pathology

  2. Linkage mapping, transcript covariance and pharmacological testing suggest that genetic variation affecting Csnk1e (show CSNK1E Antibodies) may contribute to individual differences in von Frey filament response.

  3. Loss of endothelial NO plays an important role in the generation of p25 (show CDK5R1 Antibodies) and resulting tau phosphorylation in neuronal tissue. Endothelial nitric oxide synthase (eNOS (show NOS3 Antibodies))-deficient (eNOS (show NOS3 Antibodies)-/-) mice display increased levels of p25 (show CDK5R1 Antibodies), an aberrant activator of cyclin-dependent kinase 5 (show CDK5 Antibodies), which is one of the primary kinases responsible for tau hyperphosphorylation, and a statistically higher p25/p35 (show CDK5R1 Antibodies) ratio.

  4. Fllowing severe closed head traumatic brain injury (sCHI), increasing levels of biochemically assayed T-Tau and P-Tau in the brains were associated with the PrPC (show PRNP Antibodies) expression levels, -Tau concentration in the blood was associated with PrPC (show PRNP Antibodies) expression in the absence of significant T-Tau changes; relationship was demonstrated between the presence/absence of PrPC (show PRNP Antibodies), the levels of P-Tau and cognitive dysfunction

  5. cognitive decline was significantly correlated with increased levels of caspase (show CASP3 Antibodies) activity and tau truncated by caspase-3 (show CASP3 Antibodies)

  6. Orthopedic surgery induces Abeta (show APP Antibodies) accumulation and tau phosphorylation in the hippocampus.

  7. Cadmium induces cell death on cholinergic neurons through blockade of M1 receptor, overexpression of AChE-S and GSK-3beta (show GSK3b Antibodies), down-regulation of AChE-R and increase in Abeta (show APP Antibodies) and total and phosphorylated tau protein levels.

  8. geniposide may regulate tau phosphorylation through leptin (show LEP Antibodies) signaling

  9. an inverse correlation was found between Ang-(1 (show ANGPT1 Antibodies)-7) level and tau hyperphosphorylation, a pathological hallmark of Alzheimer's disease, in cerebral cortex and hippocampus of SAMP8 mice.

  10. APP (show APP Antibodies), tau, and synaptophysin (show SYP Antibodies) were elevated in in the medial preoptic area in both the B6D2F1 and BXB1 maters relative to the B6D2F1 and BXB1 non-maters,suggesting a potential genetic mechanism for inheritance of steroid-independent male sexual behavior.

Human Microtubule-Associated Protein tau (MAPT) interaction partners

  1. In fact, DnaJC5 (show DNAJC5 Antibodies) overexpression induced tau release in cells, neurons, and brain tissue, but only when activity of the chaperone Hsc70 (show HSPA8 Antibodies) was intact and when tau was able to associate with this chaperone.

  2. Surprisingly, the authors discover that Pin1 (show PIN1 Antibodies) does not promote phosphorylated tau-induced microtubule formation in vitro, refuting the commonly accepted model in which Pin1 (show PIN1 Antibodies) binding and catalysis on the A180 epitope restores the function of the Alzheimer's associated phosphorylated tau in tubulin (show TUBB Antibodies) assembly.

  3. Importantly, site-specific measurements of Pin1 (show PIN1 Antibodies)-catalysis of CDK2 (show CDK2 Antibodies)/CycA (show CCNA2 Antibodies)-phosphorylated full-length tau reveal a number of sites that are catalyzed simultaneously with different efficiencies.

  4. Study suggests that Tau may contribute to the formation and function of the highly dynamic tunneling nanotubes that may be involved in the prion (show PRNP Antibodies)-like propagation of Tau assemblies.

  5. Established evidence from the prion (show PRNP Antibodies) field combined with the most recent tau and amyloidogenic protein research suggests that tau is a prion-like protein (show PRNP Antibodies), capable of seeding the spread of pathology throughout the brain. [review]

  6. MAPT H1c (show HIST1H1C Antibodies) haplotype (rs242557) has previously been identified as a genetic risk factor for progressive supranuclear palsy and corticobasal degeneration. The current findings suggest that plasma tau concentration could be an endophenotype for identifying risk for 4-repeat tauopathies in older individuals.

  7. 18F-AV-1451 positron emission tomography can be used to accurately quantify in vivo the regional distribution of hyperphosphorylated tau protein in MAPT mutation carriers.

  8. These results suggest that tau phosphorylation at Ser262 plays the predominant role in tau stabilization when PAR-1 (show MARK2 Antibodies)/MARK activity.

  9. Study associating lesser motor fluctuations (MFs) and non-motor predominance with cerebrospinal fluid (CSF (show CSF2 Antibodies)) tau and CSF (show CSF2 Antibodies) Abeta (show APP Antibodies), as well as with timing to, and risk of, dementia in Parkinson's disease (PD). Hence, patients with absent-to-mild MFs had older age at PD onset, higher CSF (show CSF2 Antibodies) tau markers and shorter time-to-dementia, whereas those with non-motor predominance had lower CSF (show CSF2 Antibodies) Abeta (show APP Antibodies) and greater longitudinal dementia-r...

  10. The presence of tau protein, low BDNF (show BDNF Antibodies) concentrations, and moderate/serious neurological state during the first 24 hours of stroke can be considered as negative prognosis for the patient's functional condition, and the coincidence of high BDNF (show BDNF Antibodies) concentrations and absence of tau in blood during the acute phase of an ischemic stroke is a predictor of patient's good state in 3 months after stroke.

Cow (Bovine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Findings suggest that the endothelin-1 (show EDN1 Antibodies)-induced down-regulation of NaV1.7 (SCN9A (show SCN9A Antibodies)) diminishes NaV1.7 (show SCN9A Antibodies)-related catecholamine secretion and dephosphorylation of tau.

  2. The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn (show FYN Antibodies).

  3. show that cathepsin D (show CTSD Antibodies) cleaves both tau and beta-amyloid precursor protein (APP). Both tau and APP (show APP Antibodies) are involved in the pathogenesis of Alzheimer's disease

  4. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  5. We conclude that GSK3beta (show GSK3b Antibodies) phosphorylates tau directly at S(202) but requires the previous phosphorylation on S(235) to phosphorylate T(231). Phosphorylation of S(396), on the other hand, occurs sequentially.

Rhesus Monkey Microtubule-Associated Protein tau (MAPT) interaction partners

  1. age-related increase in cAMP-dependent protein kinase (show CDK7 Antibodies) (PKA) phosphorylation of tau at serine 214 (pS214-tau) in monkey dorsolateral prefrontal association cortex specifically targets spine synapses and the Ca(2 (show CA2 Antibodies)+)-storing spine apparatus.

Chimpanzee Microtubule-Associated Protein tau (MAPT) interaction partners

  1. We found that inversion of the MAPT region is similarly polymorphic in other great ape (show CCDC88A Antibodies) species, and we present evidence that the inversions occurred independently in chimpanzees and humans

MAPT Antigen Profile

Antigen Summary

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Alternative names and synonyms associated with MAPT

  • microtubule-associated protein tau (mapt) antibody
  • microtubule-associated protein tau (MAPT) antibody
  • microtubule-associated protein tau (AaeL_AAEL015538) antibody
  • microtubule-associated protein tau (AaeL_AAEL012206) antibody
  • microtubule-associated protein tau (CpipJ_CPIJ013260) antibody
  • Microtubule-associated protein tau (tau) antibody
  • casein kinase 1, epsilon (Csnk1e) antibody
  • microtubule-associated protein tau (Mapt) antibody
  • AI413597 antibody
  • AI426939 antibody
  • AI551861 antibody
  • AW045860 antibody
  • AW457082 antibody
  • CK1epsilon antibody
  • CKIe antibody
  • DDPAC antibody
  • FTDP-17 antibody
  • KC1epsilon antibody
  • MAPT antibody
  • MAPTL antibody
  • MSTD antibody
  • Mtapt antibody
  • MTBT1 antibody
  • MTBT2 antibody
  • PHF-tau antibody
  • PPND antibody
  • pTau antibody
  • RNPTAU antibody
  • Tau antibody
  • xtp antibody

Protein level used designations for MAPT

tau-like protein , tau-like protein-2 , microtubule-associated protein tau , Microtubule-associated protein tau , CKI, epsilon , CKI-epsilon , KC1 epsilon , casein kinase I isoform epsilon , G protein beta1/gamma2 subunit-interacting factor 1 , PHF-tau , neurofibrillary tangle protein , paired helical filament-tau , microtubule associated protein tau , Neurofibrillary tangle protein , Paired helical filament-tau , Tau microtubule-associated protein

398307 Xenopus laevis
426737 Gallus gallus
5579355 Aedes aegypti
5580230 Aedes aegypti
6046480 Culex quinquefasciatus
100054638 Equus caballus
100306810 Salmo salar
27373 Mus musculus
4137 Homo sapiens
281296 Bos taurus
17762 Mus musculus
100860820 Capra hircus
29477 Rattus norvegicus
480488 Canis lupus familiaris
574327 Macaca mulatta
450177 Pan troglodytes
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