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Browse our anti-MAPT (MAPT) Antibodies

Full name:
anti-Microtubule-Associated Protein tau Antibodies (MAPT)
On www.antibodies-online.com are 1096 Microtubule-Associated Protein tau (MAPT) Antibodies from 35 different suppliers available. Additionally we are shipping MAPT Kits (60) and MAPT Proteins (45) and many more products for this protein. A total of 1244 MAPT products are currently listed.
Synonyms:
AI413597, AI426939, AI551861, AW045860, AW457082, CK1epsilon, CKIe, DDPAC, FTDP-17, KC1epsilon, MAPT, MAPTL, MSTD, Mtapt, MTBT1, MTBT2, PHF-tau, PPND, pTau, RNPTAU, Tau, xtp
list all antibodies Gene Name GeneID UniProt
MAPT 27373 Q9JMK2
MAPT 4137 P10636
MAPT 29477  

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Most Popular Reactivities for anti-MAPT (MAPT) Antibodies

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anti-Mouse (Murine) MAPT Antibodies:

anti-Human MAPT Antibodies:

anti-Rat (Rattus) MAPT Antibodies:

All available anti-MAPT Antibodies

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Top referenced anti-MAPT Antibodies

  1. Human Polyclonal MAPT Primary Antibody for EIA, IHC (p) - ABIN357423 : Yoshiyama, Zhang, Bruce, Trojanowski, Lee: Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 (PubMed)
    Show all 4 references for ABIN357423

  2. Human Polyclonal MAPT Primary Antibody for IF, IHC (p) - ABIN388782 : Horiguchi, Uryu, Giasson, Ischiropoulos, LightFoot, Bellmann, Richter-Landsberg, Lee, Trojanowski: Nitration of tau protein is linked to neurodegeneration in tauopathies. in The American journal of pathology 2003 (PubMed)
    Show all 4 references for ABIN388782

  3. Human Polyclonal MAPT Primary Antibody for EIA, WB - ABIN356907 : Beck, Rohrer, Campbell, Isaacs, Morrison, Goodall, Warrington, Stevens, Revesz, Holton, Al-Sarraj, King, Scahill, Warren, Fox, Rossor, Collinge, Mead: A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. in Brain : a journal of neurology 2008 (PubMed)
    Show all 3 references for ABIN356907

  4. Human Polyclonal MAPT Primary Antibody for ELISA, WB - ABIN1531990 : Lee, Neve, Kosik: The microtubule binding domain of tau protein. in Neuron 1990 (PubMed)
    Show all 2 references for ABIN1531990

  5. Human Polyclonal MAPT Primary Antibody for ELISA, WB - ABIN1533027 : Andreadis, Brown, Kosik: Structure and novel exons of the human tau gene. in Biochemistry 1992 (PubMed)
    Show all 2 references for ABIN1533027

  6. Human Polyclonal MAPT Primary Antibody for IHC, WB - ABIN2783223 : Reynolds, Lukas, Berry, Binder: Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms. in Biochemistry 2006 (PubMed)

  7. Human Polyclonal MAPT Primary Antibody for IHC (p), WB - ABIN388191 : McCulloch, Kay, Factor, Samii, Nutt, Higgins, Griffith, Roberts, Leis, Montimurro, Zabetian, Payami: Exploring gene-environment interactions in Parkinson's disease. in Human genetics 2008 (PubMed)

More Antibodies against MAPT Interaction Partners

Xenopus laevis Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Suppressing the expression of all tau isoforms disrupted only those neuronal microtubules containing class II beta-tubulin (show TUBB Antibodies), and that boosting the expression of the largest 'big', but not the smallest, tau isoform enhanced neurite outgrowth.

Mouse (Murine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Cadmium induces cell death on cholinergic neurons through blockade of M1 receptor, overexpression of AChE-S and GSK-3beta (show GSK3b Antibodies), down-regulation of AChE-R and increase in Abeta (show APP Antibodies) and total and phosphorylated tau protein levels.

  2. geniposide may regulate tau phosphorylation through leptin (show LEP Antibodies) signaling

  3. an inverse correlation was found between Ang-(1 (show ANGPT1 Antibodies)-7) level and tau hyperphosphorylation, a pathological hallmark of Alzheimer's disease, in cerebral cortex and hippocampus of SAMP8 mice.

  4. APP (show APP Antibodies), tau, and synaptophysin (show SYP Antibodies) were elevated in in the medial preoptic area in both the B6D2F1 and BXB1 maters relative to the B6D2F1 and BXB1 non-maters,suggesting a potential genetic mechanism for inheritance of steroid-independent male sexual behavior.

  5. These results suggested the important roles of endoplasmic reticulum-related chaperons, Bip (show HSPA5 Antibodies) and SIL1 (show SIL1 Antibodies), in Alzheimer's disease-like tau hyperphosphorylation.

  6. Findings establish CK1varepsilon as a regulator of antiviral innate immune responses and indicate a novel mechanism of immunoregulation that involves CK1varepsilon-mediated phosphorylation of TRAF3 (show TRAF3 Antibodies).

  7. This study demonstrate that phosphorylation of Tau at Serine 262 by the kinase domain of DAPK1 (show DAPK1 Antibodies) mediates spine damage and the subsequent neuronal death in ischemic stroke.

  8. mice bearing a short-period mutation in the enzyme casein kinase 1epsilon (tau mutation), which accelerates free-running circadian cycles, were investigated.

  9. we provide an in vitro model suitable for understanding disrupted MAPT splicing in FTD (show FTL Antibodies).

  10. Gene expression of Tau, a neuronal phosphoprotein with important roles in neuronal biology and microtubule dynamics and assembly, was high in wild-type molars but severely reduced in transgenic(Col1a1 (show COL1A1 Antibodies)-Runx2 (show RUNX2 Antibodies)) molars.

Human Microtubule-Associated Protein tau (MAPT) interaction partners

  1. In 3xTg-AD transgenic mice, carrying three transgenes encoding APPSWE, S1M146V, and TauP301L proteins, accumulation of Abeta (show APP Antibodies) triggers an inflammatory environment revealed by the activation of astrocytes, the expression of inflammatory cytokines (TNF-alpha (show TNF Antibodies) and IL-18 (show IL18 Antibodies)), which might be involved in the activation of SAPK (show MAPK9 Antibodies)/JNK (show MAPK8 Antibodies) and Cdk5 (show CDK5 Antibodies), leading to a sequential hyperphosphorylation of TauP301L as a function of age

  2. Data support the idea that sequestration of ERalpha (show ESR1 Antibodies) by tau protein underlies the loss of estrogen neuroprotection during the course of Alzheimer's disease.

  3. According to the flow-related diverging dynamics of blood-derived and brain-derived proteins in CSF (show CSF2 Antibodies), the concentrations of Tau and pTau tended to be lower in lumbar compared to cisternal CSF (show CSF2 Antibodies) fractions after a spinal tap of 40 ml. The differences reached statistical significance for pTau only. The small differences will not affect clinical interpretation of markers of dementia in the vast majority of cases

  4. This study supported that BIN1 (show BIN1 Antibodies) contributes to the risk of Alzheimer's disease by altering neural degeneration (abnormal tau, brain atrophy and glucose metabolism) but not Abeta (show APP Antibodies) pathology

  5. This study demostrated that MAPT rs1052553 not association in patient with essential tremor.

  6. Data suggest that an important step in the misfold- ing of Tau is the intramolecular compaction of aggregation-prone regions of Tau. Notably, formation of an intramolecular crosslink between the two native cysteines at position 291 and 322 delays aggregation of Tau, indicating that a specific con (show DISP1 Antibodies)- formational change triggers Tau misfolding, while disulfide bond formation locks Tau into an aggregation-incompetent state.

  7. Results demonstrate the differential effects of Alzheimer's disease biomarkers p-tau and amyloid-beta on brain functional connectivity networks, supporting a possible division of labour between the cardinal (show CARD8 Antibodies) pathologies

  8. Study showed that in clinical practice, extremely high CSF (show CSF2 Antibodies) Tau levels are mainly related to diagnosis of Alzheimer's disease. Creutzfeldt-Jakob disease patients represent a minority. Results support a sequential interpretation algorithm for CSF (show CSF2 Antibodies) biomarkers in dementia. High CSF (show CSF2 Antibodies) Tau levels should alert clinicians to check the p-Tau/Tau ratio to consider a probable diagnosis of Creutzfeldt-Jakob disease.

  9. showing that common variants in SNCA (show SNCA Antibodies) and MAPT genes contribute to variability in progression of parkinson disease.

  10. Data show that a homogeneous population of Tau fibrils composed of the truncated version K18 (show KRT18 Antibodies) (residues 244-372) gradually converted to a new set of fibril conformers when subjected to multiple cycles of seeding and growth.

Cow (Bovine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Findings suggest that the endothelin-1 (show EDN1 Antibodies)-induced down-regulation of NaV1.7 (SCN9A (show SCN9A Antibodies)) diminishes NaV1.7 (show SCN9A Antibodies)-related catecholamine secretion and dephosphorylation of tau.

  2. The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn (show FYN Antibodies).

  3. show that cathepsin D (show CTSD Antibodies) cleaves both tau and beta-amyloid precursor protein (APP). Both tau and APP (show APP Antibodies) are involved in the pathogenesis of Alzheimer's disease

  4. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  5. We conclude that GSK3beta (show GSK3b Antibodies) phosphorylates tau directly at S(202) but requires the previous phosphorylation on S(235) to phosphorylate T(231). Phosphorylation of S(396), on the other hand, occurs sequentially.

Rhesus Monkey Microtubule-Associated Protein tau (MAPT) interaction partners

  1. age-related increase in cAMP-dependent protein kinase (show CDK7 Antibodies) (PKA) phosphorylation of tau at serine 214 (pS214-tau) in monkey dorsolateral prefrontal association cortex specifically targets spine synapses and the Ca(2 (show CA2 Antibodies)+)-storing spine apparatus.

Chimpanzee Microtubule-Associated Protein tau (MAPT) interaction partners

  1. We found that inversion of the MAPT region is similarly polymorphic in other great ape (show CCDC88A Antibodies) species, and we present evidence that the inversions occurred independently in chimpanzees and humans

MAPT Antigen Profile

Antigen Summary

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Alternative names and synonyms associated with MAPT

  • microtubule-associated protein tau (mapt) antibody
  • microtubule-associated protein tau (MAPT) antibody
  • microtubule-associated protein tau (AaeL_AAEL015538) antibody
  • microtubule-associated protein tau (AaeL_AAEL012206) antibody
  • microtubule-associated protein tau (CpipJ_CPIJ013260) antibody
  • Microtubule-associated protein tau (tau) antibody
  • casein kinase 1, epsilon (Csnk1e) antibody
  • microtubule-associated protein tau (Mapt) antibody
  • AI413597 antibody
  • AI426939 antibody
  • AI551861 antibody
  • AW045860 antibody
  • AW457082 antibody
  • CK1epsilon antibody
  • CKIe antibody
  • DDPAC antibody
  • FTDP-17 antibody
  • KC1epsilon antibody
  • MAPT antibody
  • MAPTL antibody
  • MSTD antibody
  • Mtapt antibody
  • MTBT1 antibody
  • MTBT2 antibody
  • PHF-tau antibody
  • PPND antibody
  • pTau antibody
  • RNPTAU antibody
  • Tau antibody
  • xtp antibody

Protein level used designations for MAPT

tau-like protein , tau-like protein-2 , microtubule-associated protein tau , Microtubule-associated protein tau , CKI, epsilon , CKI-epsilon , KC1 epsilon , casein kinase I isoform epsilon , G protein beta1/gamma2 subunit-interacting factor 1 , PHF-tau , neurofibrillary tangle protein , paired helical filament-tau , microtubule associated protein tau , Neurofibrillary tangle protein , Paired helical filament-tau , Tau microtubule-associated protein

GENE ID SPECIES
398307 Xenopus laevis
426737 Gallus gallus
5579355 Aedes aegypti
5580230 Aedes aegypti
6046480 Culex quinquefasciatus
100054638 Equus caballus
100306810 Salmo salar
27373 Mus musculus
4137 Homo sapiens
281296 Bos taurus
17762 Mus musculus
100860820 Capra hircus
29477 Rattus norvegicus
480488 Canis lupus familiaris
574327 Macaca mulatta
450177 Pan troglodytes
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