MAPT antibody (pSer396)

Catalog No. ABIN7268523

The Rabbit Monoclonal anti-MAPT antibody (ABIN7268523) specifically detects MAPT in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for MAPT antibody (pSer396) (ABIN7268523)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAPT Antibody

Binding Specificity: pSer396

Purpose: Phospho-Tau-S396 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S396 of human Tau

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: MAPT

Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU,Apoptosis,Cell Biology & Developmental Biology,Cell Type Marker,Cell Type Marker_Axon marker,Cell Type Marker_Neural Stem Cell marker,Cell Type Marker_Neuron marker,Cytoskeleton,Cytoskeleton_Microtubules,MAPK-P38 Signaling Pathway,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Protein phosphorylation,Signal Transduction,Stem Cells,MAPT

Molecular Weight: 50-80kDa

Gene ID: 4137

UniProt: P10636

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size