Browse our MAPT (MAPT) ELISA Kits

Full name:
Microtubule-Associated Protein tau ELISA Kits (MAPT)
On www.antibodies-online.com are 76 Microtubule-Associated Protein tau (MAPT) ELISA Kits from 15 different suppliers available. Additionally we are shipping MAPT Antibodies (1091) and MAPT Proteins (61) and many more products for this protein. A total of 1271 MAPT products are currently listed.
Synonyms:
AI413597, AI426939, AI551861, AW045860, AW457082, CK1epsilon, CKIe, DDPAC, FTDP-17, KC1epsilon, MAPT, MAPTL, MSTD, Mtapt, MTBT1, MTBT2, PHF-tau, PPND, pTau, RNPTAU, Tau, xtp
list all ELISA KIts Gene Name GeneID UniProt
MAPT 27373 Q9JMK2
MAPT 4137 P10636
MAPT 29477  

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Top referenced MAPT ELISA Kits

  1. Rat (Rattus) MAPT ELISA Kit for Sandwich ELISA - ABIN416529 : Ekici, Uysal, Cikriklar, Özbek, Turgut Cosan, Baydemir, Kazanci, Hafizo?lu: Effect of etanercept and lithium chloride on preventing secondary tissue damage in rats with experimental diffuse severe brain injury. in European review for medical and pharmacological sciences 2014 (PubMed)

More ELISA Kits for MAPT Interaction Partners

Xenopus laevis Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Suppressing the expression of all tau isoforms disrupted only those neuronal microtubules containing class II beta-tubulin (show TUBB ELISA Kits), and that boosting the expression of the largest 'big', but not the smallest, tau isoform enhanced neurite outgrowth.

Mouse (Murine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. ROS (show ROS1 ELISA Kits) produced by 1,2-diacetylbenzene causes tau hyperphosphorylation via GSK-3beta (show GSK3b ELISA Kits) phosphorylation and it might be related to impaired memory deficit.

  2. tau overexpression mediates the excitatory toxicity induced by E-NMDAR (show GRIN1 ELISA Kits) activation through inhibiting ERK (show EPHB2 ELISA Kits) phosphorylation.

  3. Data suggest that a presumed diffusion barrier within axon initial segment (AIS (show AR ELISA Kits)) regulates wild-type Tau sorting: retrograde (axon-to-soma) and anterograde (soma-to-axon) sorting of Tau. Tau isoforms without N-terminal inserts are sorted efficiently into axons; a longer isoform (2N4R-Tau) is partially retained in cell bodies/dendrites and accelerates spine/dendrite growth.

  4. Upregulating HSF1 (show HSF1 ELISA Kits) relieves the tau toxicity in N2a-TauRD DeltaK280 by reducing CHOP (show DDIT3 ELISA Kits) and increasing HSP70 (show HSP70 ELISA Kits) a5 (BiP/GRP78 (show HSPA5 ELISA Kits)). Our work reveals how the bidirectional crosstalk between the two stress response systems promotes early tau pathology and identifies HSF1 (show HSF1 ELISA Kits) being one likely key player in both systems.

  5. Results may provide support for the hypothesis that enhanced expression of tau following lipopolysaccharide administration is a protective measure by hippocampal neurons to compensate for the loss of the microtubule-stabilizing protein due to phosphorylation. More importantly, our results support the hypothesis that blocking the production of Abeta (show APP ELISA Kits) that follows inflammation also leads to reduced tau phosphorylation

  6. Study identified microtubule-associated protein tau as a highly sensitive constituent of the cytoskeleton in the presence of experimental stroke, thus providing novel evidence for a pivotal role of cytoskeletal elements under ischemic conditions

  7. These findings suggest that TDP-43 (show TARDBP ELISA Kits) promotes tau exon 10 inclusion and 4R-tau expression and that disease-related changes of TDP-43 (show TARDBP ELISA Kits), truncations and mutations, affect its function in tau exon 10 splicing, possibly because of TDP-43 (show TARDBP ELISA Kits) mislocalization to the cytoplasm.

  8. Abeta (show APP ELISA Kits) monomers physiologically favor Tau activity and dendritic sprouting, whereas their excess causes Tau pathology

  9. Linkage mapping, transcript covariance and pharmacological testing suggest that genetic variation affecting Csnk1e (show CSNK1E ELISA Kits) may contribute to individual differences in von Frey filament response.

  10. Loss of endothelial NO plays an important role in the generation of p25 (show CDK5R1 ELISA Kits) and resulting tau phosphorylation in neuronal tissue. Endothelial nitric oxide synthase (eNOS (show NOS3 ELISA Kits))-deficient (eNOS (show NOS3 ELISA Kits)-/-) mice display increased levels of p25 (show CDK5R1 ELISA Kits), an aberrant activator of cyclin-dependent kinase 5 (show CDK5 ELISA Kits), which is one of the primary kinases responsible for tau hyperphosphorylation, and a statistically higher p25/p35 (show CDK5R1 ELISA Kits) ratio.

Human Microtubule-Associated Protein tau (MAPT) interaction partners

  1. The data of this study provided strong evidence that soluble forms of tau and Abeta (show APP ELISA Kits) co-localise early in AD and are closely linked to disease progression and cognitive decline.

  2. the influence of the p.A152T MAPT variant on the clinical and neuropathological features of these Basque GRN (show GRN ELISA Kits) families, is reported.

  3. Dual co-expression of human fetal Tau with PKA in Escherichia coli results in multisite Tau phosphorylation including also naturally occurring sites which were not previously considered in the context of 14-3-3 (show YWHAQ ELISA Kits) binding. Tau protein co-expressed with PKA displays tight functional interaction with 14-3-3 (show YWHAQ ELISA Kits) isoforms of a different type.

  4. the presence of a C-terminal pseudorepeat region (PRR (show PVRL1 ELISA Kits)) greatly increased MT binding by a greater-than-sixfold reduction of the dissociation rate. Bioinformatic analysis revealed that the PRR (show PVRL1 ELISA Kits) contained a highly conserved motif of 18 amino acids. Disease-associated tau mutations in the PRR (show PVRL1 ELISA Kits) (K369I, G389R) did not influence apparent MT binding but increased its dynamicity.

  5. In human amyloid precursor protein (show APP ELISA Kits) (hAPP) transgenic mice, co-expression of hTau-A152T enhances risk of early death and epileptic activity, suggesting copathogenic interactions between hTau-A152T and amyloid-beta peptides or other hAPP metabolites.

  6. HumanTau(AT) causes excitotoxicity mediated by NR2B (show GRIN2B ELISA Kits)-containing NMDA receptors due to enhanced extracellular glutamate (show GRIN1 ELISA Kits).

  7. ROS (show ROS1 ELISA Kits) produced by 1,2-diacetylbenzene causes tau hyperphosphorylation via GSK-3beta (show GSK3b ELISA Kits) phosphorylation and it might be related to impaired memory deficit.

  8. A phosphomimetic mutation S262E within tau microtubule-binding sites impairs EB1 (show MAPRE2 ELISA Kits)/tau interaction. This S262E-tau mutant does not inhibit the formation of EB comets. Our results further show that the parameters of microtubule dynamics change depending on the combined activities of EB1 (show MAPRE2 ELISA Kits) and tau proteins. Taken together, our data support a novel mechanism by which tau directly regulates EB1 (show MAPRE2 ELISA Kits) properties at microtubule ends.

  9. Our data suggest that although (18)F-AV-1451 SUVR curves do not reach a plateau and are still increasing in AD, an SUVR calculated over an imaging window of 80-100 min (as currently used in clinical studies) provides estimates of paired helical filament tau burden in good correlation with BPND, whereas SUVR sensitivity to regional cerebral blood changes needs further investigation.

  10. common in cognitively normal older adults. However, evidence of pathological effects on episodic memory has largely been limited to beta-amyloid (Abeta (show APP ELISA Kits)). Because Abeta (show APP ELISA Kits) and tau often cooccur in older adults, previous research offers an incomplete understanding of the relationship between pathology and episodic memory.

Cow (Bovine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Findings suggest that the endothelin-1 (show EDN1 ELISA Kits)-induced down-regulation of NaV1.7 (SCN9A (show SCN9A ELISA Kits)) diminishes NaV1.7 (show SCN9A ELISA Kits)-related catecholamine secretion and dephosphorylation of tau.

  2. The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn (show FYN ELISA Kits).

  3. show that cathepsin D (show CTSD ELISA Kits) cleaves both tau and beta-amyloid precursor protein (APP). Both tau and APP (show APP ELISA Kits) are involved in the pathogenesis of Alzheimer's disease

  4. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  5. We conclude that GSK3beta (show GSK3b ELISA Kits) phosphorylates tau directly at S(202) but requires the previous phosphorylation on S(235) to phosphorylate T(231). Phosphorylation of S(396), on the other hand, occurs sequentially.

Rhesus Monkey Microtubule-Associated Protein tau (MAPT) interaction partners

  1. age-related increase in cAMP-dependent protein kinase (show CDK7 ELISA Kits) (PKA) phosphorylation of tau at serine 214 (pS214-tau) in monkey dorsolateral prefrontal association cortex specifically targets spine synapses and the Ca(2 (show CA2 ELISA Kits)+)-storing spine apparatus.

Chimpanzee Microtubule-Associated Protein tau (MAPT) interaction partners

  1. We found that inversion of the MAPT region is similarly polymorphic in other great ape (show CCDC88A ELISA Kits) species, and we present evidence that the inversions occurred independently in chimpanzees and humans

MAPT Antigen Profile

Antigen Summary

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Alternative names and synonyms associated with MAPT

  • microtubule-associated protein tau (mapt) Elisa Kit
  • microtubule-associated protein tau (MAPT) Elisa Kit
  • microtubule-associated protein tau (AaeL_AAEL015538) Elisa Kit
  • microtubule-associated protein tau (AaeL_AAEL012206) Elisa Kit
  • microtubule-associated protein tau (CpipJ_CPIJ013260) Elisa Kit
  • Microtubule-associated protein tau (tau) Elisa Kit
  • casein kinase 1, epsilon (Csnk1e) Elisa Kit
  • microtubule-associated protein tau (Mapt) Elisa Kit
  • AI413597 Elisa Kit
  • AI426939 Elisa Kit
  • AI551861 Elisa Kit
  • AW045860 Elisa Kit
  • AW457082 Elisa Kit
  • CK1epsilon Elisa Kit
  • CKIe Elisa Kit
  • DDPAC Elisa Kit
  • FTDP-17 Elisa Kit
  • KC1epsilon Elisa Kit
  • MAPT Elisa Kit
  • MAPTL Elisa Kit
  • MSTD Elisa Kit
  • Mtapt Elisa Kit
  • MTBT1 Elisa Kit
  • MTBT2 Elisa Kit
  • PHF-tau Elisa Kit
  • PPND Elisa Kit
  • pTau Elisa Kit
  • RNPTAU Elisa Kit
  • Tau Elisa Kit
  • xtp Elisa Kit

Protein level used designations for MAPT

tau-like protein , tau-like protein-2 , microtubule-associated protein tau , Microtubule-associated protein tau , CKI, epsilon , CKI-epsilon , KC1 epsilon , casein kinase I isoform epsilon , G protein beta1/gamma2 subunit-interacting factor 1 , PHF-tau , neurofibrillary tangle protein , paired helical filament-tau , microtubule associated protein tau , Neurofibrillary tangle protein , Paired helical filament-tau , Tau microtubule-associated protein

GENE ID SPECIES
398307 Xenopus laevis
426737 Gallus gallus
5579355 Aedes aegypti
5580230 Aedes aegypti
6046480 Culex quinquefasciatus
100054638 Equus caballus
100306810 Salmo salar
27373 Mus musculus
4137 Homo sapiens
281296 Bos taurus
17762 Mus musculus
100860820 Capra hircus
29477 Rattus norvegicus
480488 Canis lupus familiaris
574327 Macaca mulatta
450177 Pan troglodytes
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