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Browse our MAPT Proteins (MAPT)

Full name:
Microtubule-Associated Protein tau Proteins (MAPT)
On are 43 Microtubule-Associated Protein tau (MAPT) Proteins from 11 different suppliers available. Additionally we are shipping MAPT Antibodies (1037) and MAPT Kits (60) and many more products for this protein. A total of 1211 MAPT products are currently listed.
AI413597, AI426939, AI551861, AW045860, AW457082, CK1epsilon, CKIe, DDPAC, FTDP-17, KC1epsilon, MAPT, MAPTL, MSTD, Mtapt, MTBT1, MTBT2, PHF-tau, PPND, pTau, RNPTAU, Tau, xtp
list all proteins Gene Name GeneID UniProt
MAPT 27373 Q9JMK2
MAPT 4137 P10636
MAPT 29477  

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MAPT Proteins (MAPT) by Origin

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Top referenced MAPT Proteins

  1. Human MAPT Protein expressed in Escherichia coli (E. coli) - ABIN667432 : Cross, Vial, Maccioni: A tau-like protein interacts with stress fibers and microtubules in human and rodent cultured cell lines. in Journal of cell science 1993 (PubMed)
    Show all 2 references for ABIN667432

  2. Human MAPT Protein expressed in Escherichia coli (E. coli) - ABIN2001992 : Weingarten, Lockwood, Hwo, Kirschner: A protein factor essential for microtubule assembly. in Proceedings of the National Academy of Sciences of the United States of America 1975 (PubMed)

More Proteins for MAPT Interaction Partners

Xenopus laevis Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Suppressing the expression of all tau isoforms disrupted only those neuronal microtubules containing class II beta-tubulin (show TUBB Proteins), and that boosting the expression of the largest 'big', but not the smallest, tau isoform enhanced neurite outgrowth.

Mouse (Murine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Findings establish CK1varepsilon as a regulator of antiviral innate immune responses and indicate a novel mechanism of immunoregulation that involves CK1varepsilon-mediated phosphorylation of TRAF3 (show TRAF3 Proteins).

  2. This study demonstrate that phosphorylation of Tau at Serine 262 by the kinase domain of DAPK1 (show DAPK1 Proteins) mediates spine damage and the subsequent neuronal death in ischemic stroke.

  3. mice bearing a short-period mutation in the enzyme casein kinase 1epsilon (tau mutation), which accelerates free-running circadian cycles, were investigated.

  4. we provide an in vitro model suitable for understanding disrupted MAPT splicing in FTD (show FTL Proteins).

  5. Gene expression of Tau, a neuronal phosphoprotein with important roles in neuronal biology and microtubule dynamics and assembly, was high in wild-type molars but severely reduced in transgenic(Col1a1 (show COL1A1 Proteins)-Runx2 (show RUNX2 Proteins)) molars.

  6. Tat (show TAT Proteins) associates with TAU RNA, further demonstrating that Tat (show TAT Proteins) interferes with host RNA metabolism in the absence of viral infection.

  7. Significantly increased levels of tau phosphorylated at various sites were observed in viable Akt (show AKT1 Proteins) three-isoforms conditional knockout mice.

  8. study demonstrate that H. pylori filtrate can induce Alzheimer-like tau hyperphosphorylation both in vitro and in vivo by activating GSK-3beta in neuronal cells

  9. Data show that interferon gamma (IFN-gamma (show IFNG Proteins))-induced (show SAMHD1 Proteins) tau (tau) hyperphosphorylation was associated with release of the inhibitory effect of glycogen synthase kinase 3beta function.

  10. alpha-Syn and Tau together cooperated with one another to increase the magnitude or rate of phosphorylation of the other by GSK-3beta.

Human Microtubule-Associated Protein tau (MAPT) interaction partners

  1. The results of this study suggest that the MAPT H1 haplotype increases the risk of Parkinson's disease (PD),progressive supranuclear palsy , and non-APOE (show APOE Proteins) varepsilon4 Late-Onset Alzheimer's Disease.

  2. FTD (show FTL Proteins) patients with MAPT mutation were younger, and showed more behavioral disinhibition, repetitive and stereotyped behaviours, semantic impairment and temporal predominance of atrophy. MAPT cases had tau pathology.

  3. association of both Alzheimer's disease and Parkinson's disease with the A allele of rs393152 within the extended MAPT region on chromosome 17

  4. The capacity FKBP52 to oligomerize Tau is not linked to its peptidyl-prolyl isomerase activity.

  5. These results suggest that stabilization of microtubule-unbound tau by phosphorylation at Ser262/356 via the PAR-1 (show MARK2 Proteins)/MARK may act in the initial steps of tau mismetabolism in AD pathogenesis

  6. Reduced miR (show MLXIP Proteins)-512 and the elevated expression of its targets cFLIP (show CFLAR Proteins) and MCL1 (show MCL1 Proteins) localize to neurons with hyperphosphorylated Tau protein in Alzheimer disease.

  7. Data show that activation of EphB2 receptor kinase arrests tau protein hyperphosphorylation through phosphatidylinositol 3-kinase (PI3K)/Akt protein-mediated glycogen synthase kinase-3beta (GSK-3beta) inhibition.

  8. The clinical utility of the CSF (show CSF2 Proteins) biomarkers amyloid-beta-1-42, t-tau, and p-tau (phosphorylated tau protein) for Alzheimer's disease diagnosis has been well documented; progress in use of these biomarkers for early diagnosis is discussed. [REVIEW]

  9. Although the can detect and identify some minor conformers in the cis (show CISH Proteins) form, they show that all prolines are for over 90% in the trans conformation.

  10. These findings indicate distinct neurodegenerative changes in FTD (show FTL Proteins) caused by mutant TAU and highlight the unique opportunity to use neurons differentiated from patient-specific iPSCs to identify potential targets for drug screening .

Cow (Bovine) Microtubule-Associated Protein tau (MAPT) interaction partners

  1. Findings suggest that the endothelin-1 (show EDN1 Proteins)-induced down-regulation of NaV1.7 (SCN9A (show SCN9A Proteins)) diminishes NaV1.7 (show SCN9A Proteins)-related catecholamine secretion and dephosphorylation of tau.

  2. The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn (show FYN Proteins).

  3. show that cathepsin D (show CTSD Proteins) cleaves both tau and beta-amyloid precursor protein (APP). Both tau and APP (show APP Proteins) are involved in the pathogenesis of Alzheimer's disease

  4. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  5. We conclude that GSK3beta phosphorylates tau directly at S(202) but requires the previous phosphorylation on S(235) to phosphorylate T(231). Phosphorylation of S(396), on the other hand, occurs sequentially.

Rhesus Monkey Microtubule-Associated Protein tau (MAPT) interaction partners

  1. age-related increase in cAMP-dependent protein kinase (show CDK7 Proteins) (PKA) phosphorylation of tau at serine 214 (pS214-tau) in monkey dorsolateral prefrontal association cortex specifically targets spine synapses and the Ca(2 (show CA2 Proteins)+)-storing spine apparatus.

Chimpanzee Microtubule-Associated Protein tau (MAPT) interaction partners

  1. We found that inversion of the MAPT region is similarly polymorphic in other great ape species, and we present evidence that the inversions occurred independently in chimpanzees and humans

MAPT Protein Profile

Protein Summary

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Alternative names and synonyms associated with MAPT

  • microtubule-associated protein tau (mapt)
  • microtubule-associated protein tau (MAPT)
  • microtubule-associated protein tau (AaeL_AAEL015538)
  • microtubule-associated protein tau (AaeL_AAEL012206)
  • microtubule-associated protein tau (CpipJ_CPIJ013260)
  • Microtubule-associated protein tau (tau)
  • casein kinase 1, epsilon (Csnk1e)
  • microtubule-associated protein tau (Mapt)
  • AI413597 protein
  • AI426939 protein
  • AI551861 protein
  • AW045860 protein
  • AW457082 protein
  • CK1epsilon protein
  • CKIe protein
  • DDPAC protein
  • FTDP-17 protein
  • KC1epsilon protein
  • MAPT protein
  • MAPTL protein
  • MSTD protein
  • Mtapt protein
  • MTBT1 protein
  • MTBT2 protein
  • PHF-tau protein
  • PPND protein
  • pTau protein
  • RNPTAU protein
  • Tau protein
  • xtp protein

Protein level used designations for MAPT

tau-like protein , tau-like protein-2 , microtubule-associated protein tau , Microtubule-associated protein tau , CKI, epsilon , CKI-epsilon , KC1 epsilon , casein kinase I isoform epsilon , G protein beta1/gamma2 subunit-interacting factor 1 , PHF-tau , neurofibrillary tangle protein , paired helical filament-tau , microtubule associated protein tau , Neurofibrillary tangle protein , Paired helical filament-tau , Tau microtubule-associated protein

398307 Xenopus laevis
426737 Gallus gallus
5579355 Aedes aegypti
5580230 Aedes aegypti
6046480 Culex quinquefasciatus
100054638 Equus caballus
100306810 Salmo salar
27373 Mus musculus
4137 Homo sapiens
281296 Bos taurus
17762 Mus musculus
100860820 Capra hircus
29477 Rattus norvegicus
480488 Canis lupus familiaris
574327 Macaca mulatta
450177 Pan troglodytes
Selected quality suppliers for MAPT Proteins (MAPT)
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