MAPT Protein (Transcript Variant 6) (His tag)
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- Target See all MAPT Proteins
- MAPT (Microtubule-Associated Protein tau (MAPT))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 6
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MAPT protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MAPT / TAU (transcript variant 6) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product MAPT Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MAPT (Microtubule-Associated Protein tau (MAPT))
- Alternative Name
- Mapt,tau (MAPT Products)
- Synonyms
- DDPAC Protein, FTDP-17 Protein, MAPTL Protein, MSTD Protein, MTBT1 Protein, MTBT2 Protein, PPND Protein, TAU Protein, AI413597 Protein, AW045860 Protein, Mtapt Protein, Tau Protein, RNPTAU Protein, pTau Protein, tau Protein, xtp Protein, MAPT Protein, PHF-tau Protein, slc6a6 Protein, taut Protein, wu:fc26e12 Protein, microtubule associated protein tau Protein, microtubule-associated protein tau Protein, microtubule associated protein tau S homeolog Protein, Microtubule-associated protein tau Protein, solute carrier family 6 (neurotransmitter transporter), member 6b Protein, MAPT Protein, Mapt Protein, mapt.S Protein, LOC5580230 Protein, CpipJ_CPIJ013260 Protein, tau Protein, slc6a6b Protein
- Background
- This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer&aposs disease, Pick&aposs disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
- Molecular Weight
- 15.4 kDa
- NCBI Accession
- NP_001116538
- Pathways
- MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size
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