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Browse our RGS1 Proteins (RGS1)

Full name:
Regulator of G-Protein Signaling 1 Proteins (RGS1)
On are 11 Regulator of G-Protein Signaling 1 (RGS1) Proteins from 6 different suppliers available. Additionally we are shipping RGS1 Antibodies (81) and RGS1 Kits (6) and many more products for this protein. A total of 108 RGS1 products are currently listed.
1r20, 4930415K13Rik, bl34, Gm202, ier1, ir20, RGS1, Rgsl2
list all proteins Gene Name GeneID UniProt
RGS1 240816  
RGS1 5996 Q08116
RGS1 54289 P97844

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RGS1 Proteins (RGS1) by Origin

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Top referenced RGS1 Proteins

  1. Human RGS1 Protein expressed in Escherichia coli (E. coli) - ABIN1098296 : Bowman, Campbell, Druey, Scheschonka, Kehrl, Butcher: Regulation of chemotactic and proadhesive responses to chemoattractant receptors by RGS (regulator of G-protein signaling) family members. in The Journal of biological chemistry 1998 (PubMed)
    Show all 2 references for ABIN1098296

More Proteins for RGS1 Interaction Partners

Mouse (Murine) Regulator of G-Protein Signaling 1 (RGS1) interaction partners

  1. Rgs1 has a role in leukocyte trafficking and vascular inflammation

  2. Variations in Gnai2 (show GNAI2 Proteins) and Rgs1 expression affect chemokine receptor (show CCR1 Proteins) signaling and the organization of secondary lymphoid organs.

  3. RGS1 can modulate the expression of costimulatory molecules and cytokine secretion, and interrupt Toll (show TLR4 Proteins) like receptor signal pathways, which suggest that RGS1 may play a role in regulating immune responses.

  4. Rgs1(-/-) mice possess B cells that respond excessively and desensitize improperly to the chemokines CXCL12 (show CXCL12 Proteins) and CXCL13 (show CXCL13 Proteins). Many of the B-cell follicles in the spleens of Rgs1(-/-) mice have germinal centers even in the absence of immune stimulation.

Human Regulator of G-Protein Signaling 1 (RGS1) interaction partners

  1. RGS1 as a potential marker of CRC (show CALR Proteins) tissue quality

  2. RGS1 suppresses CXCL12 (show CXCL12 Proteins)-mediated migration and AKT (show AKT1 Proteins) activation in cultured human plasmacytoma cells and plasmablasts.

  3. Rgs1 has a role in leukocyte trafficking and vascular inflammation

  4. RGS1 and TNFRSF1A (show TNFRSF1A Proteins) polymorphisms tended to be associated with reduced attack severity in Multiple sclerosis.

  5. RGS1 is largely upregulated, whereas RGS2 (show RGS2 Proteins) is downregulated in the majority of solid tumors, whereas RGS5 (show RGS5 Proteins) transcripts are greatly increased in eight subtypes of lymphoma with no reports of downregulation in hematological malignancies

  6. Markers in the RGS1 gene might be in linkage disequilibrium with a protective allele that reduces the risk of anxiety and depressive disorders.

  7. Elevated RGS1 levels profoundly reduce T cell migration to lymphoid-homing chemokines

  8. RGS1 is a novel multiple sclerosis susceptibility loci, shared with celieac disease.

  9. Overexpression of RGS1 in progenitor pro-B cells (which have little endogenous RGS1) impairs CXCL12-induced focal adhesion kinase activation, chemotaxis, and adhesion to membrane domains.

  10. RGS1 and RGS13 (show RGS13 Proteins) act together to regulate chemokine receptor (show CCR1 Proteins) signaling in human germinal center B lymphocytes and contribute significantly to the rapid desensitization of the signaling pathway.

RGS1 Protein Profile

Protein Summary

This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Alternative names and synonyms associated with RGS1

  • regulator of G-protein signaling like 1 (Rgsl1)
  • regulator of G-protein signaling 1 (RGS1)
  • regulator of G-protein signaling 1 (Rgs1)
  • regulator of G-protein signaling 1 (rgs1)
  • 1r20 protein
  • 4930415K13Rik protein
  • bl34 protein
  • Gm202 protein
  • ier1 protein
  • ir20 protein
  • RGS1 protein
  • Rgsl2 protein

Protein level used designations for RGS1

regulator of G-protein signaling 1 , regulator of G-protein signaling protein-like , regulator of G-protein signalling 1 , B-cell activation protein BL34 , early response protein 1R20 , immediate-early response 1, B-cell specific , Regulator of G-protein signaling 1-like protein

240816 Mus musculus
397336 Sus scrofa
457594 Pan troglodytes
5996 Homo sapiens
50778 Mus musculus
54289 Rattus norvegicus
424360 Gallus gallus
488585 Canis lupus familiaris
540836 Bos taurus
100034151 Equus caballus
447113 Xenopus laevis
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