RFWD3 Proteins

(Ring Finger and WD Repeat Domain 3 (RFWD3))

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.

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RFWD3 Protein (AA 1-774) (Strep Tag)

custom-made RFWD3 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3136488

starts at

$19,692.86

Plus shipping costs $50.00, if applicable $20.00 dry ice

250 μg

Shipping to: United States

Delivery in 55 to 67 Business Days

Details

RFWD3 Protein (His tag)

RFWD3 Origin: Human Host: Escherichia coli (E. coli) Recombinant ELISA, SDS, WB

Catalog No. ABIN7579222

$345.09

Plus shipping costs $50.00

100 μg

Shipping to: United States

Delivery in 12 to 15 Business Days

Details

RFWD3 Protein (AA 1-774) (Strep Tag)

custom-made RFWD3 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3094992

starts at

$19,692.86

Plus shipping costs $50.00, if applicable $20.00 dry ice

250 μg

Shipping to: United States

Delivery in 55 to 67 Business Days

Details