Browse our anti-RPS6KA3 (RPS6KA3) Antibodies

On www.antibodies-online.com are 253 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) Antibodies from 25 different suppliers available. Additionally we are shipping RPS6KA3 Proteins (14) and RPS6KA3 Kits (9) and many more products for this protein. A total of 287 RPS6KA3 products are currently listed.
Synonyms:
90kDa, CLS, D17Wsu134e, HU-3, ISPK-1, MAPKAPK1B, MPK-9, MRX19, p90-RSK2, p90rsk, pp90rsk, pp90RSK2, RPS6KA, Rps6ka-rs1, RSK, Rsk2, Rsk3, S6K-alpha3
list all antibodies Gene Name GeneID UniProt
RPS6KA3 6197 P51812
RPS6KA3 20112 Q9WUT3

Most Popular Reactivities for anti-RPS6KA3 (RPS6KA3) Antibodies

anti-Human RPS6KA3 Antibodies:

anti-Mouse (Murine) RPS6KA3 Antibodies:

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Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) interaction partners

  1. The expressions of PDK1, p-PDK1, RSK2 and p-RSK2 were all up-regulated (show PDPK1 Antibodies)in collagen-induced arthritis compared with normal. This indicated that P (show PDPK1 Antibodies)DK1/RSK2 may participate in inflammatory progress of (show PDPK1 Antibodies) RA.

  2. The purified protein can be fully activated in vitro by phosphorylation with protein kinases ERK2 (show MAPK1 Antibodies) and PDK1 (show PDPK1 Antibodies).

  3. Downregulation of Rps6ka3 is a promising strategy for the treatment of multiple sclerosis.

  4. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (show PDPK1 Antibodies))-p90 (show GPAM Antibodies) kDa ribosomal S6 kinases (Rsks) Rsk1 (show RPS6KA1 Antibodies)/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  5. RSK2 regulates craniofacial development including tooth development and patterning via novel transcriptional targets

  6. The results of this study show that RSK2 loss-of-function is associated in the dentate gyrus with multi-level alterations that encompass modifications of glutamate (show GRIN1 Antibodies) receptor channel properties, synaptic transmission.

  7. We propose that loss of function mutations in RSK2 that lead to Coffin-Lowry syndrome are related to defects in neuronal growth due to impaired RSK2-dependent PLD1 activity resulting in a reduced vesicle fusion rate and membrane supply.

  8. RSK2 interacted and phosphorylated GSK-3beta (show GSK3b Antibodies) at Ser9. Notably, GSK-3beta (show GSK3b Antibodies) phosphorylation at Ser9 was suppressed in RSK2(-/-) mouse embryonic fibroblasts.

  9. Pin1 (show PIN1 Antibodies) plays a critical role in tumorigenesis plausibly via physical interaction with RSK2 and reciprocal phosphorylation

  10. This study showed that RSK2 signaling contributes to morphine analgesia in the tail withdrawal response.

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) interaction partners

  1. Inhibition of RSK2 was used to investigate the function of RSK2 on PDK1 (show PDK1 Antibodies)-induced inflammation. The phosphorylation of RSK2 was detected when PDK1 (show PDK1 Antibodies) was inhibited. Inhibition of RSK2 reduced the PDK1 (show PDK1 Antibodies)-induced cell invasion and cytokines secretion in human rheumatoid arthritis synovial MH7A cells. In response to TNF-alpha (show TNF Antibodies), PDK1 (show PDK1 Antibodies) could phosphorylate RSK2 and activated RSK2, then promoting the activation of NF-kappaB (show NFKB1 Antibodies).

  2. Our finding demonstrates that RSK2 directly phosphorylates stathmin (show STMN1 Antibodies) and regulates microtubule polymerization to provide a pro-invasive and pro-metastatic advantage to cancer cells. Therefore, the RSK2-stathmin (show STMN1 Antibodies) pathway represents a promising therapeutic target and a prognostic marker for metastatic human cancers.

  3. we discuss the function of the RSK2 signaling axis by interactions with binding partners in cancer development--{REVIEW}

  4. Results showed that RSK2 gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  5. Upregulated expression of RSK2 is associated with breast cancer.

  6. Data show that the 90 kDa ribosomal protein S6 (show RPS6 Antibodies) kinases RSK1 (show RPS6KA1 Antibodies) and RSK2 play a key role in the homing of ovarian cancer cells in metastatic sites by regulating cell adhesion and invasion.

  7. RSK1 (show RPS6KA1 Antibodies) and 3 but not RSK2 are down-regulated in breast tumour and are associated with disease progression. RSK (show RPS6KA1 Antibodies) may be a key component in the progression and metastasis of breast cancer.

  8. This case is one of the few examples where RPS6KA3 mutations are associated with a non-specific X-linked mental retardation.

  9. Results indicate that the phosphorylation of EphA2 (show EPHA2 Antibodies) at Ser (show SIGLEC1 Antibodies)-897 is controlled by RSK (show RPS6KA1 Antibodies) and the RSK (show RPS6KA1 Antibodies)-EphA2 (show EPHA2 Antibodies) axis might contribute to cell motility and promote tumour malignant progression.

  10. miR (show MLXIP Antibodies)-191 represses proliferation in primary human fibroblasts via targeting multiple proto-oncogenes, including CDK9 (show CDK9 Antibodies), NOTCH2 (show NOTCH2 Antibodies), and RPS6KA3.

RPS6KA3 Antigen Profile

Antigen Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA3

  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) antibody
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RPS6KA1) antibody
  • ribosomal protein S6 kinase, polypeptide 2 (Rps6ka2) antibody
  • ribosomal protein S6 kinase polypeptide 3 (Rps6ka3) antibody
  • 90kDa antibody
  • CLS antibody
  • D17Wsu134e antibody
  • HU-3 antibody
  • ISPK-1 antibody
  • MAPKAPK1B antibody
  • MPK-9 antibody
  • MRX19 antibody
  • p90-RSK2 antibody
  • p90rsk antibody
  • pp90rsk antibody
  • pp90RSK2 antibody
  • RPS6KA antibody
  • Rps6ka-rs1 antibody
  • RSK antibody
  • Rsk2 antibody
  • Rsk3 antibody
  • S6K-alpha3 antibody

Protein level used designations for RPS6KA3

MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , insulin-stimulated protein kinase 1 , p90-RSK 3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase alpha-3 , MAP kinase-activated protein kinase 1 , MAPK-activated protein kinase 1 , MAPKAP kinase 1 , MAPKAPK-1 , S6KII-alpha , p90-RSK , ribosomal protein S6 kinase 2 alpha , ribosomal protein S6 kinase II alpha , 90 kDa ribosomal protein S6 kinase 2 , MAP kinase-activated protein kinase 1c , MAPK-activated protein kinase 1c , MAPKAP kinase 1c , MAPKAPK-1c , RSK-3 , S6K-alpha 2 , S6K-alpha-2 , p90-RSK 2 , p90RSK2 , pp90RSK3 , protein-tyrosine kinase Mpk-9 , ribosomal S6 kinase 3 , ribosomal protein S6 kinase alpha 2 , ribosomal protein S6 kinase alpha-2 , ribosomal protein S6 kinase, 90kD, polypeptide 2 , 90 kDa ribosomal protein S6 kinase 3 , p90RSK3 , ribosomal protein S6 kinase 2

GENE ID SPECIES
6197 Homo sapiens
386579 Gallus gallus
20112 Mus musculus
110651 Mus musculus
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