Browse our YAP1 Proteins (YAP1)

Full name:
Yes-Associated Protein 1 Proteins (YAP1)
On www.antibodies-online.com are 10 Yes-Associated Protein 1 (YAP1) Proteins from 5 different suppliers available. Additionally we are shipping YAP1 Antibodies (237) and YAP1 Kits (25) and many more products for this protein. A total of 285 YAP1 products are currently listed.
Synonyms:
AI325207, cb194, HCCA1, HCCA2, sb:cb194, si:ch211-181p1.5, si:dkey-3b8.3, wu:fc18c04, xyap, yap, YAP1, yap2, yap65, yki, Yorkie, YY1AP, zgc:158380
list all proteins Gene Name GeneID UniProt
YAP1 10413 P46937
Mouse YAP1 YAP1 22601 P46938
YAP1 363014 Q2EJA0

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YAP1 Proteins (YAP1) by Origin

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Top referenced YAP1 Proteins

  1. Human YAP1 Protein expressed in Wheat germ - ABIN1325497 : Zhao, Zhou, Xue, Zhang, Zhan: Nicotine activates YAP1 through nAChRs mediated signaling in esophageal squamous cell cancer (ESCC). in PLoS ONE 2014 (PubMed)

More Proteins for YAP1 Interaction Partners

Human Yes-Associated Protein 1 (YAP1) interaction partners

  1. Studies indicate that the transcriptional co-activators YAP and TAZ (show TAZ Proteins) recently emerged as key mediators of the biological effects that are observed in response to extracellular matrix (ECM (show MMRN1 Proteins)) elasticity and cell shape.

  2. The transcription factor YAP1 was found to be a direct target of miR (show MLXIP Proteins)-375 in prostate cancer. Knockdown of YAP1 phenocopied miR (show MLXIP Proteins)-375 overexpression, and overexpression of YAP1 rescued anti-invasive effects mediated by miR (show MLXIP Proteins)-375.

  3. YAP negatively regulated an antiviral immune response. YAP deficiency resulted in enhanced innate immunity. YAP blocked dimerization of the transcription factor IRF3 and impeded translocation of IRF3 to the nucleu (show IRF3 Proteins)s after viral infection.

  4. Galpha12/13 promotes proliferation of ovarian cancer cells by activating the transcriptional coactivator YAP, a critical component of the Hippo signaling pathway.

  5. the transcription regulators YAP and TAZ (show TAZ Proteins) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  6. The Hippo effector YAP plays a crucial role in linking the PD-L1 (show CD274 Proteins) and EGFR (show EGFR Proteins)-TKI resistance by directly regulating the expression of PD-L1 (show CD274 Proteins) in lung cancer cells.

  7. In response to TGF-beta (show TGFB1 Proteins), RASSF1A (show RASSF1 Proteins) is recruited to TGF-beta (show TGFB1 Proteins) receptor I and targeted for degradation by the co-recruited E3 ubiquitin ligase (show MUL1 Proteins) ITCH. RASSF1A (show RASSF1 Proteins) degradation is necessary to permit Hippo pathway effector YAP1 association with SMADs and subsequent nuclear translocation of receptor-activated SMAD2 (show SMAD2 Proteins).

  8. DICER1 (show DICER1 Proteins)-miR (show MLXIP Proteins)-590-5p-YAP1 axis was dysregulated in colorectal carcinoma specimens and affected patient survival. Cell-cell contact inhibition is crucial to prevent uncontrolled cell proliferation.

  9. In colorectal carcinoma TIAM1 (show TIAM1 Proteins) suppresses tumor progression by regulating YAP/TAZ (show TAZ Proteins) activity.

  10. Growing evidence suggests that transcriptional effectors of the Hippo pathway, YAP and TAZ (show TAZ Proteins), promote resistance to various anti-cancer therapies, including cytotoxic chemotherapy, molecular targeted therapy, and radiation therapy. [review]

Mouse (Murine) Yes-Associated Protein 1 (YAP1) interaction partners

  1. YAP negatively regulated an antiviral immune response. YAP deficiency resulted in enhanced innate immunity, a diminished viral load, and morbidity in vivo. YAP blocked dimerization of the transcription factor IRF3 (show IRF3 Proteins) and impeded translocation of IRF3 (show IRF3 Proteins) to the nucleus after viral infection.

  2. the transcription regulators YAP and TAZ (show TAZ Proteins) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  3. Yap and Taz (show TAZ Proteins) are activated in Schwann cells by mechanical stimuli and regulate Schwann cell proliferation and transcription of basal lamina receptor genes

  4. This paper explored the role of Yes-associated protein (Yap) in neuromuscular junction (NMJ) formation and regeneration. Yap is a major effector of the Hippo pathway that regulates cell proliferation and differentiation during development and restricts tissue growth in adult animals. However, its role in synapse formation remains poorly understood.

  5. Yap determines the regional fate of the RPE (show RPE Proteins) during early eye development. Yap is essential for maintaining apical polarity and cell to cell adhesion. Yap regulates the proliferation and survival of retinal progenitor cells. Yap has an evolutionarily conserved, instructive role in regional specification, maintenance of junctional integrity and precise regulation of cell proliferation during neuroepithelial development.

  6. our data suggest that NLK (show NLK Proteins)/Nemo (show IKBKG Proteins) acts as an endogenous regulator of Hippo signaling by controlling nuclear localization and activity of YAP/Yorkie.

  7. YAP2-5SA-DeltaC drives beta-catenin (show CTNNB1 Proteins) activity to promote basal keratinocyte proliferation in the mouse skin in vivo

  8. Hedgehog (show SHH Proteins) pathway controls Yap1 activation during liver regeneration

  9. transient expression of exogenous YAP or its closely related paralogue TAZ (show TAZ Proteins) in primary differentiated mouse cells can induce conversion to a tissue-specific stem/progenitor cell state.

  10. Thus, our findings identify an unrecognized function of neogenin (show NEO1 Proteins) in mouse neocortical astrocyte differentiation, and suggest a signaling pathway, BMP2 (show BMP2 Proteins)-neogenin (show NEO1 Proteins)-YAP-Smad1 (show SMAD1 Proteins), underlying astrogliogenesis in developing mouse neocortex.

Zebrafish Yes-Associated Protein 1 (YAP1) interaction partners

  1. that Yap1 entered the nucleus and promoted transcription in response to blood flow.

  2. that Yap1 integrates the anabolic demands of tissue growth during development and tumorigenesis by reprogramming nitrogen metabolism to stimulate nucleotide biosynthesis

  3. Amotl2a (show AMOTL2 Proteins) function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 and the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) effector Lef1 (show LEF1 Proteins).

  4. data reveals that Yap is required for pronephric duct integrity, maintenance of baso-lateral cell polarity, and ciliogenesis during zebrafish kidney development

  5. Yap/Taz (show TAZ Proteins)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  6. Yap is essential for fin regeneration and that its function is dependent on mechanical tension, conferred by a balancing act of cell density and cytoskeleton activity.

  7. When transcriptional coactivators Yap and Taz (show TAZ Proteins) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  8. Yap coordinately regulates cell proliferation and apoptosis and is required for dorsoventral axis formation, gastrulation, cardiogenesis, hematopoiesis, and somitogenesis.

  9. zebrafish yap is required for the development of the brain, eyes, and neural crest during embryogenesis.

Xenopus laevis Yes-Associated Protein 1 (YAP1) interaction partners

  1. Yap1 has a crucial role in controlling the limb regenerative capacity in Xenopus

YAP1 Protein Profile

Protein Summary

The encoded gene product presumably interacts with YY1 protein\; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with YAP1

  • Yes-associated protein 1 (YAP1)
  • Yes-associated protein 1, 65kDa (YAP1)
  • Yes-associated protein 1, 65kDa (LOC787360)
  • Yes-associated protein 1, 65kDa (LOC100219556)
  • yes-associated protein 1 (Yap1)
  • Yes-associated protein 1 (yap1)
  • Yes-associated protein 1 (Yap1)
  • YY1 associated protein 1 (YY1AP1)
  • AI325207 protein
  • cb194 protein
  • HCCA1 protein
  • HCCA2 protein
  • sb:cb194 protein
  • si:ch211-181p1.5 protein
  • si:dkey-3b8.3 protein
  • wu:fc18c04 protein
  • xyap protein
  • yap protein
  • YAP1 protein
  • yap2 protein
  • yap65 protein
  • yki protein
  • Yorkie protein
  • YY1AP protein
  • zgc:158380 protein

Protein level used designations for YAP1

Yes-associated protein 1, 65kDa , Yes-associated protein 1, 65 kD , 65 kDa Yes-associated protein , yes-associated protein 2 , yorkie homolog , yes-associated protein, 65 kDa , yap , YY1-associated protein 1 , hepatocellular carcinoma susceptibility protein , hepatocellular carcinoma-associated protein 2

GENE ID SPECIES
100068834 Equus caballus
451506 Pan troglodytes
617423 Bos taurus
787360 Bos taurus
100219556 Taeniopygia guttata
10413 Homo sapiens
22601 Mus musculus
363014 Rattus norvegicus
561411 Danio rerio
100381098 Xenopus laevis
396171 Gallus gallus
479465 Canis lupus familiaris
100336629 Bos taurus
100726570 Cavia porcellus
100913160 Ovis aries
55249 Homo sapiens
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