Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human GC Protein expressed in Human - ABIN3119689
Ramadass, Ghebrehiwet, Smith, Kew: Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies. in Journal of immunology (Baltimore, Md. : 1950) 2014
Show all 3 Pubmed References
Comparison of Two ELISA Methods and Mass Spectrometry for Measurement of Vitamin D-Binding Protein: Implications for the Assessment of Bioavailable Vitamin D Concentrations Across Genotypes.
Single-nucleotide polymorphisms in the vitamin D binding protein genewere independently associated with lower 25-hydroxy-vitamin Dand higher 24,25-dihydroxy-vitamin D.
genetic association studies in a population in Brazil: Data suggest that SNPs in RXRG (show RXRG Proteins) (rs2134095) and GC (rs7041) are associated with low-density lipoprotein cholesterol levels and hypercholesterolemia in the population studied; there was no apparent association with an SNP in VDR (show CYP27B1 Proteins) (rs2228570). (RXRG (show RXRG Proteins) = retinoid X receptor gamma (show RXRG Proteins); GC = vitamin D-binding protein; VDR (show CYP27B1 Proteins) = vitamin D receptor (show VDR Proteins))
The study strongly suggests that there might have an association of vitamin D, and vitamin D-binding protein gene (codon 416 & 420) polymorphisms with the occurrence of type 2 diabetes mellitus
Low serum vitamin D-binding protein concentrations are associated with type 1 diabetes.
rs7041 polymorphism of Vitamin D Binding Protein does not affect platelet reactivity or the rate of high-residual platelet reactivity among patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
High VDBG concentration was associated with coronary heart disease events in all racial and ethnic groups.
SNPs rs7041 and rs4588 of VDBP are not associated with the levels of 25-hydroxyvitamin D nor with the prevalence and extent of CAD. 25-hydroxyvitamin D levels but not VDBP genetic status independently predicted the occurrence of coronary lesions at angiography.
Genetic variant in vitamin D-binding protein is associated with metabolic syndrome.
Study suggests higher (versus lower) circulating DBP may be independently associated with a decreased prostate cancer risk in black men independent of 25(OH)D status.
Associations between SNPs and the studied traits were strongest for SNPs that were located within and immediately upstream of the group-specific component (GC) gene. Our results suggest GC as the gene that underlies the QTL for clinical mastitis and milk production.
Peroxisomal multifunctional protein-2 (show HSD17B4 Proteins) deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation in mice.
results show DBP is a significant chemotactic cofactor in vivo and not specific for C5a, suggesting that this ubiquitous plasma protein may have a more significant role in neutrophil recruitment than previously recognized
Data suggest that whereas DBP is important to total circulating 1,25(OH)(2)D(3) and sequesters extracellular levels of this hormone both in vivo and in vitro, the binding protein does not influence the hormone's biologically active pool.
bile acid biosynthesis, estimated by the ratio of C27/C24-bile acids, is more severely affected in double knock-out mice as compared with DBP-/- mice but was normal in LBP (show LBP Proteins)-/- mice
Peroxisomal multifunctional protein 2 (show HSD17B4 Proteins) is essential for lipid homeostasis in Sertoli cells and male fertility
Loss of MFP2 leads to attenuation of up-regulations of SREBP2 (show SREBF2 Proteins) and HMGCR (show HMGCR Proteins) involved in cholesterol synthesis.
The aim of this research was to screen polymorphism and to perform association study of porcine AMBP (show AMBP Proteins), GC and PPP1R3B (show PPP1R3B Proteins) genes with meat quality traits.
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, vitamin D-binding alpha-globulin
, vitamin D-binding protein
, D site albumin promoter binding protein
, D site-binding protein
, albumin D box-binding protein
, albumin D-element-binding protein
, d site albumin promoter-binding protein 1
, 17-beta-HSD 4
, 17-beta-hydroxysteroid dehydrogenase 4
, D-bifunctional protein
, multifunctional protein 2
, peroxisomal multifunctional enzyme type 2
, peroxisomal multifunctional enzyme type II
, group-specific component (vitamin D binding protein)
, vitamin D binding protein
, vitamin-D binding protein
, group-specific component (vitamin D binding protein) S homeolog