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Browse our anti-KIF2C (KIF2C) Antibodies

Full name:
anti-Kinesin Family Member 2C Antibodies (KIF2C)
On are 75 Kinesin Family Member 2C (KIF2C) Antibodies from 18 different suppliers available. Additionally we are shipping KIF2C Proteins (6) and many more products for this protein. A total of 91 KIF2C products are currently listed.
4930402F02Rik, ESTM5, kcm1, KIF2C, Knsl6, KRP2, mcak, MGC89391, si:ch211-61f14.1, X83316
list all antibodies Gene Name GeneID UniProt
KIF2C 11004 Q99661
KIF2C 73804 Q922S8
KIF2C 171529 Q62909

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Most Popular Reactivities for anti-KIF2C (KIF2C) Antibodies

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anti-Human KIF2C Antibodies:

anti-Mouse (Murine) KIF2C Antibodies:

anti-Rat (Rattus) KIF2C Antibodies:

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Top referenced anti-KIF2C Antibodies

  1. Human Monoclonal KIF2C Primary Antibody for IF, IHC (p) - ABIN564770 : Sanhaji, Friel, Kreis, Krämer, Martin, Howard, Strebhardt, Yuan: Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1. in Molecular and cellular biology 2010 (PubMed)
    Show all 2 references for ABIN564770

  2. Human Polyclonal KIF2C Primary Antibody for WB - ABIN657964 : Tanno, Kitajima, Honda, Ando, Ishiguro, Watanabe: Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres. in Genes & development 2010 (PubMed)
    Show all 2 references for ABIN657964

  3. Cow (Bovine) Polyclonal KIF2C Primary Antibody for WB - ABIN2778191 : Lee, Langford, Askham, Brüning-Richardson, Morrison: MCAK associates with EB1. in Oncogene 2008 (PubMed)

  4. Human Polyclonal KIF2C Primary Antibody for IF, ELISA - ABIN1532772 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

More Antibodies against KIF2C Interaction Partners

Human Kinesin Family Member 2C (KIF2C) interaction partners

  1. the Aurora B (show AURKB Antibodies)-PLK1 (show PLK1 Antibodies) signaling at the kinetochore orchestrates MCAK activity, which is essential for timely correction of aberrant kinetochore attachment to ensure accurate chromosome segregation during mitosis.

  2. MCAK activity is modulated by Plk1 (show PLK1 Antibodies) phosphorylation on S632/S633 in mitosis.

  3. These results demonstrate that the structural change of Kif2C-ATP upon binding to microtubule ends is sufficient for tubulin (show TUBB Antibodies) release, whereas ATP hydrolysis is not required

  4. Ras regulates KIF2C to control cell migration pathways in transformed human bronchial epithelial cells.

  5. A dynamic interaction of MCAK-TIP150 (show KIAA0774 Antibodies) orchestrated by Aurora A (show AURKA Antibodies)-mediated phosphorylation governs entosis via regulating microtubule plus-end dynamics and cell rigidity.

  6. this study suggests a new mechanism by which Plk1 (show PLK1 Antibodies) regulates MCAK: by regulating its degradation and hence controlling its turnover in mitosis.

  7. up-regulation of KIF2C and KIF2A by ERK1/2 caused aberrant lysosomal positioning and mTORC1 activity in a mutant K-Ras-dependent cancer and cancer model.

  8. A Rac1-Aurora A (show AURKA Antibodies)-MCAK signaling pathway mediates endothelial cell polarization and directional migration by promoting regional differences in microtubule dynamics.

  9. result suggested E403K mutation in mitotic centromere-associated kinesin protein (show KIF2B Antibodies) as highly damaging and showed strong concordance to the previously observed colorectal cancer mutations aggregation tendency and energy value changes

  10. A CENP-E (show CENPE Antibodies) mediated wall-tethering event and a MCAK-mediated wall-removing event show that human chromosome-microtubule attachment is achieved through a set of deterministic sequential events rather than stochastic direct capture of microtubule ends.

Mouse (Murine) Kinesin Family Member 2C (KIF2C) interaction partners

  1. PAK1 (show PAK1 Antibodies) phosphorylates MCAK and regulates both its localization and function.

  2. MCAK appears to possess a unique distribution and function in oocyte maturation.

  3. MCAK contributes to chromosome alignment in meiosis I, but is not necessary for preventing chromosome segregation errors.

  4. Possible functions of MCAK at the inner centromere domain and at the perikinetochoric ring during both meiotic divisions.

  5. Shugoshin 2 (show SGOL2 Antibodies) is necessary for the loading of MCAK at the inner centromere, but is dispensable for the loading of the outer kinetochore proteins BubR1 (show BUB1B Antibodies) and CENP-E (show CENPE Antibodies).

Xenopus laevis Kinesin Family Member 2C (KIF2C) interaction partners

  1. MCAK colocalized with NuMA (show NUMA1 Antibodies) and XMAP215 (show CKAP5 Antibodies) at the center of Ran asters where its activity is regulated by Aurora A (show AURKA Antibodies)-dependent phosphorylation of S196, which contributes to proper pole focusing

  2. This study reveals a new role for Aurora B (show AURKB Antibodies), which is to prevent excess MCAK binding to chromatin to facilitate chromatin-nucleated spindle assembly.

  3. MCAK regulation of cytoplasmic and spindle-associated (show HAUS1 Antibodies) microtubules can be differentiated by Aurora B (show AURKB Antibodies)-dependent phosphorylation

  4. These data support a model in which Nup98 (show NUP98 Antibodies) interacts with microtubules and antagonizes MCAK activity, thus promoting bipolar spindle assembly.

KIF2C Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.

Alternative names and synonyms associated with KIF2C

  • kinesin family member 2C (KIF2C) antibody
  • kinesin family member 2C (kif2c) antibody
  • kinesin family member 2C (Kif2c) antibody
  • 4930402F02Rik antibody
  • ESTM5 antibody
  • kcm1 antibody
  • KIF2C antibody
  • Knsl6 antibody
  • KRP2 antibody
  • mcak antibody
  • MGC89391 antibody
  • si:ch211-61f14.1 antibody
  • X83316 antibody

Protein level used designations for KIF2C

kinesin family member 2C , kinesin-like protein KIF2C , kinesin-like protein KIF2C-like , kinesin-like 6 , kinesin-like protein 6 , mitotic centromere-associated kinesin , MCAK , kinesin-related protein 2 , Kinesin-like protein 6 , kinesin central motor 1 , xKCM1

424583 Gallus gallus
448620 Xenopus (Silurana) tropicalis
456548 Pan troglodytes
475382 Canis lupus familiaris
705381 Macaca mulatta
100014033 Monodelphis domestica
100052754 Equus caballus
100136875 Danio rerio
100391603 Callithrix jacchus
100461300 Pongo abelii
100474833 Ailuropoda melanoleuca
100516205 Sus scrofa
100558145 Anolis carolinensis
100590717 Nomascus leucogenys
11004 Homo sapiens
73804 Mus musculus
171529 Rattus norvegicus
533161 Bos taurus
100689309 Cricetulus griseus
380006 Xenopus laevis
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