Browse our anti-KIF2C (KIF2C) Antibodies

On are 88 Kinesin Family Member 2C (KIF2C) Antibodies from 20 different suppliers available. Additionally we are shipping KIF2C Proteins (6) and many more products for this protein. A total of 106 KIF2C products are currently listed.
4930402F02Rik, ESTM5, kcm1, KIF2C, Knsl6, KRP2, mcak, MGC89391, si:ch211-61f14.1, X83316
list all antibodies Gene Name GeneID UniProt
KIF2C 11004 Q99661
KIF2C 73804 Q922S8
KIF2C 171529 Q62909

Most Popular Reactivities for anti-KIF2C (KIF2C) Antibodies

anti-Human KIF2C Antibodies:

anti-Mouse (Murine) KIF2C Antibodies:

anti-Rat (Rattus) KIF2C Antibodies:

All available anti-KIF2C Antibodies

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More Antibodies against KIF2C Interaction Partners

Human Kinesin Family Member 2C (KIF2C) interaction partners

  1. REVIEW: Conformation changes in MCAK related to its depolymerization activity and function are described. A model of its regulation by multiple mitotic kinases is proposed and its potential involvement in oncogenesis and drug resistance its highlighted.

  2. GTSE1 (show GTSE1 Antibodies) inhibition of MCAK activity regulates the balance of MT stability that determines the fidelity of chromosome alignment, segregation, and chromosomal stability.

  3. MCAC (show SLC25A20 Antibodies) role in microtubule assembly

  4. Our results reveal an underlying mechanism by which NuSAP (show NUSAP1 Antibodies) controls kinetochore microtubule dynamics spatially and temporally by modulating the depolymerisation function of MCAK in an Aurora B kinase (show AURKB Antibodies)-dependent manner.

  5. MCAK is involved in directional migration and invasion of tumor cells.

  6. the Aurora B (show AURKB Antibodies)-PLK1 (show PLK1 Antibodies) signaling at the kinetochore orchestrates MCAK activity, which is essential for timely correction of aberrant kinetochore attachment to ensure accurate chromosome segregation during mitosis.

  7. MCAK activity is modulated by Plk1 (show PLK1 Antibodies) phosphorylation on S632/S633 in mitosis.

  8. These results demonstrate that the structural change of Kif2C-ATP upon binding to microtubule ends is sufficient for tubulin (show TUBB Antibodies) release, whereas ATP hydrolysis is not required

  9. Ras regulates KIF2C to control cell migration pathways in transformed human bronchial epithelial cells.

  10. A dynamic interaction of MCAK-TIP150 (show KIAA0774 Antibodies) orchestrated by Aurora A (show AURKA Antibodies)-mediated phosphorylation governs entosis via regulating microtubule plus-end dynamics and cell rigidity.

Mouse (Murine) Kinesin Family Member 2C (KIF2C) interaction partners

  1. PAK1 (show PAK1 Antibodies) phosphorylates MCAK and regulates both its localization and function.

  2. MCAK appears to possess a unique distribution and function in oocyte maturation.

  3. MCAK contributes to chromosome alignment in meiosis I, but is not necessary for preventing chromosome segregation errors.

  4. Possible functions of MCAK at the inner centromere domain and at the perikinetochoric ring during both meiotic divisions.

  5. Shugoshin 2 (show SGOL2 Antibodies) is necessary for the loading of MCAK at the inner centromere, but is dispensable for the loading of the outer kinetochore proteins BubR1 (show BUB1B Antibodies) and CENP-E (show CENPE Antibodies).

Xenopus laevis Kinesin Family Member 2C (KIF2C) interaction partners

  1. MCAK colocalized with NuMA (show NUMA1 Antibodies) and XMAP215 (show CKAP5 Antibodies) at the center of Ran asters where its activity is regulated by Aurora A (show AURKA Antibodies)-dependent phosphorylation of S196, which contributes to proper pole focusing

  2. This study reveals a new role for Aurora B (show AURKB Antibodies), which is to prevent excess MCAK binding to chromatin to facilitate chromatin-nucleated spindle assembly.

  3. MCAK regulation of cytoplasmic and spindle-associated (show HAUS1 Antibodies) microtubules can be differentiated by Aurora B (show AURKB Antibodies)-dependent phosphorylation

  4. These data support a model in which Nup98 (show NUP98 Antibodies) interacts with microtubules and antagonizes MCAK activity, thus promoting bipolar spindle assembly.

KIF2C Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.

Alternative names and synonyms associated with KIF2C

  • kinesin family member 2C (KIF2C) antibody
  • kinesin family member 2C (kif2c) antibody
  • kinesin family member 2C (Kif2c) antibody
  • 4930402F02Rik antibody
  • ESTM5 antibody
  • kcm1 antibody
  • KIF2C antibody
  • Knsl6 antibody
  • KRP2 antibody
  • mcak antibody
  • MGC89391 antibody
  • si:ch211-61f14.1 antibody
  • X83316 antibody

Protein level used designations for KIF2C

kinesin family member 2C , kinesin-like protein KIF2C , kinesin-like protein KIF2C-like , kinesin-like 6 , kinesin-like protein 6 , mitotic centromere-associated kinesin , MCAK , kinesin-related protein 2 , Kinesin-like protein 6 , kinesin central motor 1 , xKCM1

424583 Gallus gallus
448620 Xenopus (Silurana) tropicalis
456548 Pan troglodytes
475382 Canis lupus familiaris
705381 Macaca mulatta
100014033 Monodelphis domestica
100052754 Equus caballus
100136875 Danio rerio
100391603 Callithrix jacchus
100461300 Pongo abelii
100474833 Ailuropoda melanoleuca
100516205 Sus scrofa
100558145 Anolis carolinensis
100590717 Nomascus leucogenys
11004 Homo sapiens
73804 Mus musculus
171529 Rattus norvegicus
533161 Bos taurus
100689309 Cricetulus griseus
380006 Xenopus laevis
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