Browse our PKC eta Proteins (PRKCH)

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Protein Kinase C, eta Proteins (PRKCH)
On are 12 Protein Kinase C, eta (PRKCH) Proteins from 8 different suppliers available. Additionally we are shipping PKC eta Antibodies (97) and PKC eta Kits (15) and many more products for this protein. A total of 137 PKC eta products are currently listed.
nPKC-eta, pkc-eta, PKC-L, Pkch, PKCL, prkch, PRKCL, si:ch211-212g7.5, zgc:172124
list all proteins Gene Name GeneID UniProt
PRKCH 5583 P24723
PRKCH 18755 P23298
PRKCH 81749 Q64617

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PKC eta Proteins (PRKCH) by Origin

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Human Protein Kinase C, eta (PRKCH) interaction partners

  1. The association between PRKCH 1425G/A and lacunar infarction was independent of traditional stroke risk factors

  2. Data suggest that targeted manipulation of protein kinase C isoforms PKCalpha (show PKCa Proteins), PKCbeta, and PKCeta might be beneficial in certain proteinuric kidney diseases with altered transient receptor potential cation channel subfamily C member 6 (show TRPC6 Proteins) protein (TRPC6 (show TRPC6 Proteins)) functions.

  3. variant genotypes of PRKCH 1425G/A are an independent prognostic factor for ischemic stroke in the final multivariate Cox (show COX8A Proteins) regression model

  4. Meta-analysis indicated that the 1425G/A SNP in PRKCH may contribute to susceptibility of stroke, especially for ischemic stroke.

  5. PKCeta promotes senescence through its ability to upregulate the expression of the cell cycle inhibitors p21Cip1 (show CDKN1A Proteins) and p27Kip1 (show CDKN1B Proteins) and enhance transcription and secretion of IL-6 (show IL6 Proteins).

  6. The 1425G/A polymorphism in PRKCH is not a significant predictor of stroke recurrence in patients with acute ischemic stroke during a 2-year follow-up period.

  7. PKC-eta associates with NHE3 (show SLC9A3 Proteins) and gamma tubulin (show TUBG1 Proteins) to promote the cell polarity during migration.

  8. the PKC family genes may play a role in the pathogenesis of MS relapse through modulating the association between 25(OH)D and relapse.

  9. Upregulation of PKCeta contributes to breast cancer cell growth and targeting either PKCepsilon (show PRKCE Proteins) or PDK1 (show PDK1 Proteins) triggers PKCeta downregulation

  10. study demonstrates that type V collagen induces the down-regulation of protein kinase C eta

Mouse (Murine) Protein Kinase C, eta (PRKCH) interaction partners

  1. genetic deficiency results in defective suppressive activity of T reg (show KCNH2 Proteins) cells

  2. data suggest that PKCeta shares some redundant roles with PKCtheta (show PRKCQ Proteins); in T cell biology and also performs nonredundant functions that are required for T cell homeostasis and activation

  3. Protein kinase C eta promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 (show CDKN1B Proteins) mRNA through suppression of JNK/c-Jun signaling under stress conditions.

  4. these results establish a previously uncharacterized role forPKC-epsilon, PKC-eta, PKC-theta (show PRKCQ Proteins) in T cell polarity.

  5. ATP1A1 (show ATP1A1 Proteins) interaction with PKCeta and occludin (show OCLN Proteins) was involved in the integrity of the blood-labyrinth-barrier

  6. PKC-eta/Fyn (show FYN Proteins)-dependent pathway leading to keratinocyte growth arrest and differentiation

  7. The expression of specific PKC isotypes was significantly changed as embryonic stem cells differentiated into cardiomyocytes.

  8. Parvovirus infection was found to result in activation of both PDK1 (show PDPK1 Proteins) and PKCeta, as evidenced by changes in their subcellular distribution and overall (auto)phosphorylation.

  9. directs the induction of IRF-4 (show IRF4 Proteins) expression downstream of BLNK (show BLNK Proteins) in the pre-BCR (show BCR Proteins) signaling pathway promoting kappa gene rearrangement

  10. Translational regulation could provide an additional level for controlling the expression of PKC family members.

PKC eta (PRKCH) Protein Profile

Protein Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Alternative names and synonyms associated with PKC eta (PRKCH)

  • protein kinase C, eta (prkch)
  • protein kinase C, eta (PRKCH)
  • protein kinase C, eta, b (prkchb)
  • protein kinase C, eta, a (prkcha)
  • protein kinase C, eta (Prkch)
  • nPKC-eta protein
  • pkc-eta protein
  • PKC-L protein
  • Pkch protein
  • PKCL protein
  • prkch protein
  • PRKCL protein
  • si:ch211-212g7.5 protein
  • zgc:172124 protein

Protein level used designations for Protein Kinase C, eta Proteins (PRKCH)

protein kinase C, eta , protein kinase C eta type , protein kinase C eta type-like , PKC-L , nPKC-eta , protein kinase C-eta

444221 Xenopus laevis
490722 Canis lupus familiaris
556591 Danio rerio
746068 Pan troglodytes
100051560 Equus caballus
100144561 Danio rerio
100151731 Xenopus (Silurana) tropicalis
100410970 Callithrix jacchus
100474521 Ailuropoda melanoleuca
100545425 Meleagris gallopavo
100586510 Nomascus leucogenys
5583 Homo sapiens
18755 Mus musculus
81749 Rattus norvegicus
423518 Gallus gallus
100344184 Oryctolagus cuniculus
518542 Bos taurus
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