Browse our ITGB3BP Proteins (ITGB3BP)

Full name:
Integrin beta 3 Binding Protein (Beta3-Endonexin) Proteins (ITGB3BP)
On are 9 Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) Proteins from 4 different suppliers available. Additionally we are shipping ITGB3BP Antibodies (38) and ITGB3BP Kits (16) and many more products for this protein. A total of 66 ITGB3BP products are currently listed.
4930471O16Rik, AU022583, CENP-R, CENPR, HSU37139, NRIF3, TAP20
list all proteins Gene Name GeneID UniProt
ITGB3BP 23421 Q13352
ITGB3BP 67733 Q9CQ82
ITGB3BP 362548 Q5U1Z7

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ITGB3BP Proteins (ITGB3BP) by Origin

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More Proteins for ITGB3BP Interaction Partners

Human Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) interaction partners

  1. The beta3-endonexin can act as a novel anti-angiogenic factor (show VEGFA Proteins) specifically in the response to hypoxia due to its negative impact on the activation of HIF-1 (show HIF1A Proteins).

  2. Data propose that CENP-P (show CENPP Proteins)/O/R/Q/U self-assembles on kinetochores with varying stoichiometry and undergoes a pre-mitotic maturation step that could be important for kinetochores switching into the correct conformation for microtubule-attachment.

  3. The presence of various isoforms and the relationship between subcellular localization and integrin-activating function of beta(3)-endonexin is described.

  4. This protein downregulates urokinase-type plasminogen activator receptor (show PLAUR Proteins) promoter activity.

  5. Results suggest that breast cancer cells contain a novel "death switch" that can be specifically triggered by NRIF3 or death domain 1.

  6. Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator

  7. findings suggest that NRIF3-Ser28 is a physiologic target of Pak1 (show PAK1 Proteins) signaling and contributes to the enhanced NRIF3 co-activator activity, leading to coordinated potentiation of ERalpha (show ESR1 Proteins) transactivation

Mouse (Murine) Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) interaction partners

  1. in contrast to uPAR (show PLAUR Proteins) or NF-kappaB (show NFKB1 Proteins), the expression of beta(3)-endonexin was reduced in extracts of advanced atherosclerotic aortic tissue

ITGB3BP Protein Profile

Protein Summary

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with ITGB3BP

  • integrin beta 3 binding protein (beta3-endonexin) (ITGB3BP)
  • integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp)
  • 4930471O16Rik protein
  • AU022583 protein
  • CENP-R protein
  • CENPR protein
  • HSU37139 protein
  • NRIF3 protein
  • TAP20 protein

Protein level used designations for ITGB3BP

beta 3 endonexin , beta-3-endonexin , centromere protein R , integrin beta-3-binding protein , nuclear receptor-interacting factor 3 , CENP-R , beta3-endonexin

23421 Homo sapiens
67733 Mus musculus
362548 Rattus norvegicus
424689 Gallus gallus
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