ITGB3BP Protein (AA 1-216) (His tag)
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- Target See all ITGB3BP Proteins
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-216
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ITGB3BP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMPFAPVA QARVQWHDFR SLQHLLPAFK RFSCLSLGSS WDYSVKRSLK LDGLLEENSF DPSKITRKKS VITYSPTTGT CQMSLFASPT SSEEQKHRNG LSNEKRKKLN HPSLTESKES TTKDNDEFMM LLSKVEKLSE EIMEIMQNLS SIQALEGSRE LENLIGISCA SHFLKREMQK TKELMTKVNK QKLFEKSTGL PHKASRHLDS YEFLKAILN
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ITGB3BP Protein
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Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-177) protein (GST tag)
ITGB3BP Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-100) protein (GST tag)ITGB3BP Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 78-177) protein (GST tag)ITGB3BP Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-176) protein (Strep Tag)Crystallography grade ITGB3BP Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-177) protein (Strep Tag)Crystallography grade ITGB3BP Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) protein (Myc-DYKDDDDK Tag)ITGB3BP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
- Alternative Name
- ITGB3BP (ITGB3BP Products)
- Synonyms
- CENP-R Protein, CENPR Protein, HSU37139 Protein, NRIF3 Protein, TAP20 Protein, 4930471O16Rik Protein, AU022583 Protein, integrin subunit beta 3 binding protein Protein, integrin beta 3 binding protein (beta3-endonexin) Protein, ITGB3BP Protein, Itgb3bp Protein
- Background
- Cntromere protein R isoform 1, also known as ITGB3BP1, is a widely expressed protein that contains a DD1 or RepD1 domain and an LXXLL motif. Induced by estrogen, ITGB3BP1 is believed to function as a nuclear receptor coactivator. It also associates with the CENP-A-CAD complex which is involved in mitotic progression, the assembly of kinetochore proteins and chromosome segregation. It acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Recombinant human ITGB3BP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 27.1 kDa (239aa)
- NCBI Accession
- NP_001193668
- UniProt
- Q13352
- Pathways
- Neurotrophin Signaling Pathway
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