Browse our anti-KALRN (KALRN) Antibodies

Full name:
anti-Kalirin, RhoGEF Kinase Antibodies (KALRN)
On are 63 Kalirin, RhoGEF Kinase (KALRN) Antibodies from 16 different suppliers available. Additionally we are shipping KALRN Kits (3) and and many more products for this protein. A total of 73 KALRN products are currently listed.
2210407G14Rik, ARHGEF24, AV235988, cb248, CHD5, CHDS5, DUET, Duo, dZ106A20.1, E530005C20Rik, Gm539, Hapip, Kalirin, KALRN, sb:cb248, si:dz42h5.2, si:dz106a20.1, si:dz106a20.2, sol, TRAD
list all antibodies Gene Name GeneID UniProt
KALRN 8997 O60229
KALRN 545156 A2CG49
KALRN 84009 P97924

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anti-Human KALRN Antibodies:

anti-Mouse (Murine) KALRN Antibodies:

anti-Rat (Rattus) KALRN Antibodies:

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Top referenced anti-KALRN Antibodies

  1. Cow (Bovine) Polyclonal KALRN Primary Antibody for ELISA - ABIN451733 : Xie, Srivastava, Photowala, Kai, Cahill, Woolfrey, Shum, Surmeier, Penzes: Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines. in Neuron 2007 (PubMed)

  2. Human Polyclonal KALRN Primary Antibody for IHC (p), IHC - ABIN188543 : Colomer, Engelender, Sharp, Duan, Cooper, Lanahan, Lyford, Worley, Ross: Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain. in Human molecular genetics 1998 (PubMed)

More Antibodies against KALRN Interaction Partners

Human Kalirin, RhoGEF Kinase (KALRN) interaction partners

  1. Data suggest protein levels of kalirin and CHD7 (show CHD7 Antibodies) in circulating extracellular vesicles (EVs) as endothelial dysfunction markers to monitor vascular condition in hypertensive patients with albuminuria.

  2. GG genotype and the G allele of the rs9289231 polymorphism of KALRN and the rs224766 polymorphism of ADIPOQ (show ADIPOQ Antibodies) genes may be considered genetic risk factors for Iranian type 2 diabetic patients with coronary artery disease.

  3. 4 KALRN gene SNPs were studied in Han ischemic stroke patients. rs11712619 seemed associated with lacunar stroke until risk factors were considered. re6438833 was significantly associated with ischemic and lacunar stroke.

  4. consider the GG genotype and the G allele of rs9289231 polymorphism of KALRN to be genetic risk factors for CAD (show CAD Antibodies) in an Iranian population, especially in early-stage atherosclerotic vascular disease

  5. A sequence variant in human KALRN impairs protein ability to activate Rac1 and coincides with reduced cortical thickness.

  6. The kalirin expression were reduced in Alzheimer disease with psychosis.

  7. The age-at-onset of Huntington disease (HD (show HTT Antibodies)) is not associated with eleven SNPs, including SNP rs10934657 in the kalirin gene in 680 European HD patients.

  8. Neuronal guanine nucleotide exchange factor (show NGEF Antibodies) (GEF (show SLC2A4RG Antibodies)) kalirin is emerging as a key regulator of structural and functional plasticity at dendritic spines.

  9. In both anterior cingulate cortex (ACC) and dorsolateral prefrontal cortex (DLPFC), study found a reduction of Duo expression and PAK1 phosphorylation in schizophrenia. Cdc42 protein expression was decreased in ACC but not in DLPFC

  10. Missense mutations in KALRN may be genetic risk factors for schizophrenia.

Mouse (Murine) Kalirin, RhoGEF Kinase (KALRN) interaction partners

  1. Kalirin-7 plays a prominent role in nociceptive sensitization via activity-dependent modulation of spinal synapses.

  2. lack of Kalrn expression in POMC (show POMC Antibodies) cells closely mimicked the effects of global Kalrn knockout on anxiety-like behavior and passive avoidance conditioning

  3. Kalirin may play a role in paracrine and/or endocrine signaling events that control skeletal bone remodeling and the maintenance of bone mass.

  4. Many of the widespread and diverse deficits observed both within and outside of the nervous system when expression of Kalrn is eliminated may reflect its role in secretory granule function and its expression outside of the nervous system.

  5. Kalirin functions as a guanine nucleotide exchange factor for Rac1 in smooth muscle cells, promoting migration and proliferation.

  6. Kalirin-7 is an selectively essential modulator of NMDA receptor-dependent synaptic plasticity in the hippocampus.

  7. Identification of kalirin-7 as a potential post-synaptic density signaling hub

  8. This study demonstrated a novel and functionally important interaction between the NR2B (show GRIN2B Antibodies) subunit of the NMDA receptor and Kalirin, proteins known to be essential for normal synaptic plasticity.

  9. These data suggest that hippocampal structure and function are more resilient to the complete loss of kalirin, and reveal impairments in fear learning.

  10. Thus cocaine-mediated changes in alternative splicing of the Kalrn gene may contribute importantly to the behavioral, morphological and biochemical responses observed.

KALRN Antigen Profile

Antigen Summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with KALRN

  • kalirin, RhoGEF kinase (KALRN) antibody
  • SEC14 and spectrin domains 1 (sestd1) antibody
  • kalirin, RhoGEF kinase (kalrn) antibody
  • kalirin (Smp_162970) antibody
  • kalirin, RhoGEF kinase (Kalrn) antibody
  • 2210407G14Rik antibody
  • ARHGEF24 antibody
  • AV235988 antibody
  • cb248 antibody
  • CHD5 antibody
  • CHDS5 antibody
  • DUET antibody
  • Duo antibody
  • dZ106A20.1 antibody
  • E530005C20Rik antibody
  • Gm539 antibody
  • Hapip antibody
  • Kalirin antibody
  • KALRN antibody
  • sb:cb248 antibody
  • si:dz42h5.2 antibody
  • si:dz106a20.1 antibody
  • si:dz106a20.2 antibody
  • sol antibody
  • TRAD antibody

Protein level used designations for KALRN

SEC14 domain and spectrin repeat-containing protein 1 , solo , protein Solo , huntingtin-associated , kalirin, RhoGEF kinase , kalirin-like , kalirin , huntingtin-associated protein interacting protein (duo) , serine/threonine kinase with Dbl- and pleckstrin homology domains , serine/threonine-protein kinase with Dbl- and pleckstrin homology domain , protein Duo , serine/threonine kinase with Dbl- and pleckstrin homology domain , P-CIP10 , PAM COOH-terminal interactor protein 10 , cyclin B1 , huntingtin-associated protein-interacting protein

100060560 Equus caballus
360133 Danio rerio
424253 Gallus gallus
460643 Pan troglodytes
478592 Canis lupus familiaris
548783 Xenopus (Silurana) tropicalis
100158344 Xenopus laevis
100473997 Ailuropoda melanoleuca
100557732 Anolis carolinensis
8353820 Schistosoma mansoni
8997 Homo sapiens
545156 Mus musculus
540675 Bos taurus
84009 Rattus norvegicus
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